The importance of IgG N-glycosylation in Health, Disease, and Neonatal hemochromatosis
December 2025
Neonatal hemochromatosis (NH) is a unique disease with an unknown etiology, characterized by neonatal liver failure (NLF) and associated with iron deposition in the fetal liver and extrahepatic organs,...
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AJDW, polysaccharide from Albizia julibrissin, binds to PI3K and induces cell cycle arrest and ROS-mediated pancreatic cancer cell apoptosis
December 2025
To understand the material basis of the extraction from Albizia julibrissin, a traditional oriental medicine that has reported antitumor activity, a novel neutral polysaccharide fraction and its anti-pancreatic...
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Dietary glycans and their role in human health: implications for gut health, metabolism, and functional foods
December 2025
Dietary glycans, a diverse class of carbohydrate-based biomolecules, play a crucial role in human health by modulating gut microbiota, enhancing immune responses, and influencing metabolic processes....
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Expression patterns, structural features, and roles of SRPX2 in disease pathogenesis
December 2025
SRPX2 (Sushi Repeat-Containing Protein X-Linked 2) is a multifunctional regulatory protein that has recently been implicated in various pathological conditions, including tumorigenesis, neurodevelopmental...
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A cancer vaccine based on N-linked sialyl-Tn antigen elicits robust and selective antitumor immunity
Available online 18 August 2025
Cancer vaccines hold great promise for cancer prevention and treatment. Tumor-associated carbohydrate antigens (TACAs) are attractive targets for cancer vaccine development, yet suffer from their inherent...
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