Macro to micro: A perspective on cell-directed physical therapy for next-generation rehabilitation
September 2026
Development and internal validation of a Nomogram-based risk prediction model for post-stroke cognitive impairment
September 2026
Post-stroke cognitive impairment (PSCI) severely affects patients' quality of life and survival, and no curative treatment is currently available. Therefore, early detection and prevention are cruc...
Structural changes in nursing charges under diagnosis-related group (DRG) payment: A retrospective observational study in a tertiary general hospital in China
September 2026
In the context of diagnosis-related group (DRG) payment, evidence on structural changes in nursing charge composition in general wards remains limited....
Central sensitization and opioid-sparing multimodal analgesia: An editorial perspective on restructuring perioperative pain management
September 2026
Central sensitization as the mechanistic thread linking phase-specific multimodal analgesia to functional recovery....
Adverse childhood experiences and suicide attempts in rural China: Case–control study on roles of negative life events and psychological factors
September 2026
While adverse childhood experiences (ACEs) increase suicide attempt risk, the psychosocial pathways underlying this association remain unclear....
Continuous glucose monitoring time in range, glycemic parameters for diabetic retinopathy in type 2 diabetes: A systematic review and meta-analysis
September 2026
Many patients with type 2 diabetes (T2D) develop diabetic retinopathy (DR) despite achieving target glycated hemoglobin (HbA1c) levels. Continuous glucose monitoring (CGM)-derived metrics capture glucose...
Automatic classification of medical literature leveraging pre-trained large language models
September 2026
Identifying clinical research articles can facilitate evidence synthesis and research evaluation; however, journal categories and keyword-based approaches may not accurately capture studies at the article...
The conceptualization of safe care for older inpatients: A model based on socio-ecological theory
June 2026
Safe care for older adults is a crucial component of clinical practice. Understanding the conceptual connotation of safe care for older hospitalized patients can help improve the safety of geriatric...
Association between cognitive function and hip fracture among middle-aged and older Chinese adults: A prospective study using the China Health and Retirement Longitudinal Study
June 2026
The relationship between cognitive function and hip fracture risk among middle-aged and older adults in China remains unclear, with limited longitudinal evidence....
Crossing borders, challenging boundaries: Bridging scientific boundaries in rehabilitation nursing
June 2026
The effects of virtual reality on cancer-related pain and anxiety: A systematic review and meta-analysis of randomized controlled trials
June 2026
Cancer-related pain and anxiety are highly prevalent and inadequately managed. Virtual reality (VR) has emerged as a promising nonpharmacological intervention. However, its effectiveness remains un...
Comparative efficacy of virtual reality and noninvasive brain stimulation on cognitive impairment after stroke: A systematic review and network meta-analysis
June 2026
Post-stroke cognitive impairment (PSCI) is common and lacks well-established non-pharmacological treatment recommendations. Virtual reality (VR) and noninvasive brain stimulation (NIBS) are increasingly...
Evidence for the causal relationship between age at first sexual intercourse and multidimensional aging phenotypes from a full life cycle perspective: A mendelian randomization study
March 2026
The full life cycle perspective emphasizes the profound impact of early-life events on later health. Age at first sexual intercourse (AFS) marks the onset of an individual’s sexual development and behavior,...
A rehabilitation design concept based on brain–computer interface and McKibben artificial muscle
March 2026
This perspective proposes a restrained rehabilitation design that reframes an electroencephalography (EEG)-based brain–computer interface (BCI) from continuous motor control to an intention-gating signal...
Effects of home-based strength training with different intensities on muscle strength and physical functions in patients with Duchenne muscular dystrophy: Study protocol for an exploratory pilot randomized controlled trial
March 2026
Regular submaximal strengthening exercises are recommended for patients with Duchenne muscular dystrophy (DMD); however, evidence regarding the optimal intensity is limited....
Construction of risky sexual behaviors intervention program for college students based on Behavior Change Wheel theory: A mixed-methods study
March 2026
Risky sexual behaviors (RSBs) among college students pose a substantial threat to both physical and mental health and are associated with sexually transmitted infections and unintended pregnancies....
Neuromodulation therapy for phantom limb pain: A review of the current status and future perspectives
March 2026
Phantom Limb Pain (PLP) is a common and intractable neuropathic pain condition that occurs following limb amputation, significantly impacting patients’ quality of life. The prevalence of PLP ranges...
Comparative study of demographic information, clinical scales and questionnaires, and mobility tests for fall risk assessment in older adults
March 2026
Falls are the leading cause of injury and mortality in older adults; however, the relative contributions of different fall risk factor domains remain unclear. A past fall history strongly predicts future...
Fatigue and associated factors among middle-aged patients with breast cancer undergoing chemotherapy in China: A cross-sectional study
October 2025
Fatigue is a prevalent and burdensome symptom in patients with breast cancer undergoing chemotherapy, and middle-aged women may be especially vulnerable....
Exploring Ilaprazole-CYP2C19 interaction: A computational study on metabolic stability and drug-drug interaction potential
October 2025
Proton pump inhibitors (PPIs) have been shown to reduce the therapeutic efficacy and alter the clinical outcomes of co-administered medications due to cytochrome P450 family 2 subfamily C member 19...
Effect of caregiver burden on subjective well-being among caregivers of older patients with multiple chronic conditions in Chinese rural areas
October 2025
Rural caregivers of older patients with multiple chronic conditions bear a substantial caregiver burden. Self-efficacy and family support may mediate the relationship between caregiver burden and subjective...
Unveiling core symptoms and gender-specific patterns of cyber-deviance in adolescents with obesity: A cross-sectional study using network analysis
October 2025
Cyber-deviance is widespread among adolescents with obesity; however, its core symptoms and network structure remain unknown....
Intermittent hypoxia promotes fatty acid metabolism and improves myocardial energy homeostasis potentially via AMPKα1 pathway
October 2025
Myocardial infarction (MI) disrupts cardiac energy metabolism and mitochondrial function. Intermittent hypoxia (IH) may confer cardioprotection. This study investigated whether IH improves myocardial...