Reciprocal neuro-cardiovascular interactions in ischemic stroke and Alzheimer’s disease: a cross-organ framework of acute and chronic energetic stress
Available online 8 August 2026
Ischemic stroke and Alzheimer's disease (AD) are leading causes of neurological disability and cognitive decline, respectively. Although traditionally studied as distinct disorders, growing evidence...
Humanized mouse models for autoimmune diseases
Available online 8 August 2026
Humanized mouse models can mimic the human immune system, making them useful for investigating the pathogenesis of autoimmune diseases and developing therapeutic strategies. These models bridge the...
Dose–response relationship between adverse childhood experiences and digestive diseases among Chinese adults: the mediating role of depression
Available online 1 August 2026
Adverse childhood experiences (ACEs) have been associated with various adverse health outcomes, potentially including digestive diseases. We conducted a population-based cross-sectional study aimed...
A comparative analysis of flexible endoscopic evaluation of swallowing characteristics before and after decannulation in patients with neurogenic dysphagia undergoing tracheostomy: a retrospective study
Available online 31 July 2026
Tracheostomy is commonly performed in patients with a range of diseases. However, the relationship between tracheostomy and dysphagia remains controversial. Therefore, we conducted this retrospective...
Repeated administration of human umbilical cord mesenchymal stem cells promotes motor function recovery correlated with diffusion tensor imaging in a canine model of spinal cord injury
Available online 28 July 2026
Diffusion tensor imaging (DTI) can clearly and comprehensively reveal the subtle pathology of damaged spinal cord. However, the correlation between motor function recovery and dynamic changes in DTI...
Motor performance and cortical neural activity during exercise in patients with different levels of post-stroke fatigue
Available online 28 July 2026
Post-stroke fatigue (PSF) can independently predict mortality in patients with stroke. The effect of PSF on the process of exercise and the nature of PSF remain unclear. This study investigated differences...
Differential cortical activation and functional connectivity induced by immersive and semi-immersive virtual reality: a functional near-infrared spectroscopy study
Available online 28 July 2026
The impact of virtual reality (VR) on cognitive and motor processes has recently gained considerable attention. We aimed to perform a comparative analysis of the neurophysiological responses evoked...
Subarachnoid transplantation of allogeneic human umbilical cord mesenchymal stem cells to treat late chronic spinal cord injury: Protocol for a prospective, multicenter, open-label, single-arm clinical study
Available online 28 July 2026
Spinal cord injury (SCI) is a devastating condition characterized by extensive cellular death, axonal disruption, and scar formation, resulting in lifelong disability, muscle spasms, sensory deficits,...