Vitamins strategies for psoriasis: An update on current scientific evidence
December 2023
Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...
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Study on the application of Aloe vera in cosmetology and clinical treatment of skin diseases
December 2024
The medicinal value of Aloe vera (AV) has been continuously explored and utilized in recent years, becoming a research hotspot. Some basic studies have found that AV had cosmetic effects such as whitening,...
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Deciphering the anti-senescence immune paradigm: Kidney yin-yang equilibrium in traditional Chinese medicine
June 2024
In traditional Chinese medicine (TCM), the kidney is considered the "innate foundation", and the abundance or diminution of its essence directly affects the growth, development, physical form, and physiological...
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Research on the role and mechanism of Aloe vera (L.) Burm.f. in the treatment of burn: Based on network pharmacology analysis and experimental verification
December 2024
Burn is a suddenly occurring injury. The healing process of burn is complex. Aloe vera (L.) Burm.f. (Av) is widely used as Chinese folk medicine for the treatment of burn. While effective pharmacological...
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The versatility of apigenin: Especially as a chemopreventive agent for cancer
December 2024
Apigenin, a naturally occurring flavonoid found in fruits and vegetables, has received substantial attention due to its various pharmacological effects, particularly in cancer therapy. This review delves...
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Genomics-based tools for drug discovery and development: From network maps to efficacy prediction
November 2023
Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools...
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Study on the synergistic development of TCM service trade within the GBA
November 2023
This study analyzed the synergistic development of the Traditional Chinese Medicine (TCM) service trade within the Greater Bay Area (GBA) in China, aiming to provide suggestions and references for the...
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Human Epididymis Protein 4 (HE4) as a promising biomarker and therapy target in fibrotic diseases: A review
December 2024
The treatment of fibrosis faces a significant challenge due to the lack of effective therapies that can reverse established fibrosis. Early detection is vital for intervention, yet distinguishing fibrosis...
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Visual analysis of drug research and development based on artificial intelligence
December 2024
The iteration of artificial intelligence (AI) technology provides new opportunities for drug research and experimental development. In recent years, AI-based drug research has continuously made new...
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Development of ginger oleoresin-enriched marshmallow candy as a nutraceutical for managing pediatric chemotherapy-induced nausea and vomiting
March 2025
Chemotherapy-induced nausea and vomiting (CINV) significantly impact pediatric cancer patients, affecting treatment adherence and quality of life. This study aimed to develop gingerol-enriched marshmallow...
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Pedalitin could regulate lipid metabolism and attenuate inflammatory factors in a non-alcoholic fatty liver disease cell model
December 2024
Nonalcoholic fatty liver disease (NAFLD) is an escalating global health issue, leading to liver fat accumulation, inflammation, fibrosis, and potential liver failure. In our preliminary network pharmacological...
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Peptide drugs application in metabolic diseases and discovery strategies
March 2022
Peptides (or polypeptides) are generally defined as those molecules compounded with less than 100 amino acids linked by peptide bonds, and the relative molecular weight is less than 10 000 Da usually....
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Network pharmacology-based study on the mechanism of Yiwei Decoction in chronic atrophic gastritis and experimental assessment
December 2024
Yiwei Decoction (YWD) is an ancient TCM formula with historical use in treating chronic atrophic gastritis (CAG). However, its pharmacodynamic mechanisms remain poorly understood. This study aims to...
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The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
September 2024
Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine...
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Truxillic and truxinic acid derivatives: configuration, source, and bioactivities of natural cyclobutane dimers
September 2020
Natural truxillic and truxinic acid derivatives are interesting cyclobutane dimers, with different stereo conformations formed by the orientation of groups on the cyclobutane. These derivatives are...
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Anticancer flavonoids producing endophytic fungi: A review
December 2024
Plants living in different environments inhabit endophytic microbes. The relationship between plants and endophytic microbes may be symbiotic or parasitic. Transmission of endophytes varies when they...
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Secondary metabolites from the cold-seep-derived fungus Penicillium sp. SCSIO 41425 and their free radical scavenging activity
December 2024
To study the chemical compositions from Penicillium sp. SCSIO 41425 and explore their DPPH radical scavenging activity....
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Enlightenment of EU Herbal Medicinal Products regulation on the registration of Traditional Chinese Medicines in the Guangdong-Hong Kong-Macao Greater Bay Area
December 2024
This study analyzes the European Union's (EU's) regulatory practices of Herbal Medicinal Products (HMPs), aiming to provide implications for Traditional Chinese Medicines (TCMs) registration process...
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Economic evaluation of isosorbide mononitrate sustained-release capsules for the treatment of angina pectoris
March 2024
Systematically evaluate the efficacy of (1) isosorbide mononitrate sustained-release capsules combined with conventional therapy and (2) conventional therapy alone in the treatment of angina pectoris...
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Review of compounds and activities from mangrove Sonneratia genus and their endophytes
November 2023
Sonneratia is an important mangrove plant, and its fruit has been used as traditional medicine and food in southeast China. With recent research focusing on its compounds and activities, an increasing...
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Formulation and evaluation of carbamazepine loaded ethosomal nasal in-situ gel for brain targeted drug delivery
March 2025
This study aimed to develop a novel intranasal drug delivery system for carbamazepine, an antiepileptic drug, to enhance its therapeutic efficacy through targeted and sustained delivery. The goal was...
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Review on application and development of pharmacogenomics of adverse drug reactions
March 2025
Adverse drug reactions (ADRs) are a significant public health issue, contributing substantially to patient morbidity and mortality. The growing accessibility of genomic technologies has greatly advanced...
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Unravelling the gut-liver axis: The role of gut microbiota-mitochondria interactions in the pathogenesis and management of metabolic-associated fatty liver disease (MAFLD)
March 2025
Metabolic-associated fatty liver disease (MAFLD) has emerged as a prevalent chronic liver disease. Our review of the existing literature reveals that the interplay between gut microbiota, mitochondria,...
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The repair effect of α-ketoglutarate combined with mesenchymal stem cells on osteoarthritis via the hedgehog protein pathway
March 2025
Mesenchymal stem cell (MSC) therapy represents a promising treatment strategy for osteoarthritis (OA). Nevertheless, the therapeutic efficacy of MSCs may be attenuated under conditions of cellular senescence...
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The functions and applications of organoids in rheumatic immune diseases
June 2024
Rheumatic immune disorders are a group of conditions that affect the immune system, leading to various clinical symptoms. These diseases can cause pain, reduce the quality of life, and increase the...
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