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ISSN: 3117-9282

Mitochondrial oxidative stress in rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis: From pathogenic mechanisms to therapeutic prospects

Autoimmune diseases feature chronic inflammation driven by aberrant immune activation and constitute a major global health burden. Mitochondrial oxidative stress arises from the imbalance between mitochondrial...

ATP-induced cell death: Mechanistic framework, evidence-graded gene landscape, and the ATPexGen resource

ATP-induced cell death (AICD) is an operational conceptual framework describing the associations between pathological extracellular ATP accumulation, excessive purinergic stimulation, disrupted ATP...

Frontiers in brain science and multi-omics: From atlas construction to functional testing and translational research

Brain science is entering an era in which single-cell, single-nucleus, spatial, and multimodal omics can be interpreted within a shared biological framework. Recent studies have extended brain atlases...

Multimodal AI for cardiovascular care must learn when not to predict

Old data, new problem: rethinking public database research in the era of generative AI

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