Ketone bodies in metabolism and signaling: Revisiting the paradigm from biochemistry to pancreatic β-cell regulation
June 2026
Ketone bodies, long viewed through the lens of the ketotoxic paradigm, are now being recognized as multifaceted molecules with roles extending far beyond energy substrates. The biochemistry of ketogenesis...
GLP-1 medicine and non-arteritic anterior ischemic optic neuropathy: Literature review and perspectives
June 2026
GLP-1 therapeutics (defined as GLP-1 medicine hereafter), including GLP-1 receptor (GLP-1R) agonists (i.e. semaglutide) and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor dual agonist...
24-epibrassinolide drives female germline stem cell development via NMT1-mediated in situ interaction between Gm26624 and Abcg2
June 2026
Recent studies indicate that approximately 15% of couples worldwide are affected by infertility. The discovery of female germline stem cells (FGSCs) offers a promising new therapeutic strategy for infertility...
Integrating multi-omics and digital phenotyping for precision care in gestational diabetes
June 2026
Gestational diabetes mellitus (GDM) is a prevalent and heterogeneous pregnancy complication that elevates cardiometabolic risk for both mother and child. Conventional diagnostic and treatment approaches...
Circulating folate forms and diabetic comorbidities: US National health and nutrition examination survey, 2011–2018
June 2026
To investigate the associations between circulating folate forms and the prevalence of diabetic comorbidities among U.S. adults....
Phytochemicals alter foam cell formation and macrophage cholesterol efflux
June 2026
The accumulation of cholesterol within arterial macrophages, resulting from disrupted processes of cholesterol uptake, esterification, and efflux, is a critical factor in foam cell formation and the...
Association of triglyceride-glucose index with incident fracture risk and bone mineral density in the UK Biobank
September 2026
This study aims to investigate the association between the triglyceride-glucose (TyG) index and incident fracture risk, as well as bone mineral density (BMD), in a large prospective cohort from the...