GLP-1 medicine and non-arteritic anterior ischemic optic neuropathy: Literature review and perspectives
June 2026
GLP-1 therapeutics (defined as GLP-1 medicine hereafter), including GLP-1 receptor (GLP-1R) agonists (i.e. semaglutide) and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor dual agonist...
Integrating multi-omics and digital phenotyping for precision care in gestational diabetes
June 2026
Gestational diabetes mellitus (GDM) is a prevalent and heterogeneous pregnancy complication that elevates cardiometabolic risk for both mother and child. Conventional diagnostic and treatment approaches...
Phytochemicals alter foam cell formation and macrophage cholesterol efflux
June 2026
The accumulation of cholesterol within arterial macrophages, resulting from disrupted processes of cholesterol uptake, esterification, and efflux, is a critical factor in foam cell formation and the...
24-epibrassinolide drives female germline stem cell development via NMT1-mediated in situ interaction between Gm26624 and Abcg2
June 2026
Recent studies indicate that approximately 15% of couples worldwide are affected by infertility. The discovery of female germline stem cells (FGSCs) offers a promising new therapeutic strategy for infertility...
Ketone Bodies in Metabolism and Signaling: Revisiting the Paradigm from Biochemistry to Pancreatic β-Cell Regulation
Available online 14 April 2026
Ketone bodies, long viewed through the lens of the ketotoxic paradigm, are now being recognized as multifaceted molecules with roles extending far beyond energy substrates. The biochemistry of ketogenesis...