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ISSN: 3117-8170

Recent research progress of plant-derived chlorogenic acid in cancer therapy: Anticancer mechanism and combination therapy

Chlorogenic acid (CGA), a natural hydroxycinnamic phenolic acid, is widely found in coffee, Eucommia ulmoides leaves and potatoes. Numerous studies have highlighted that CGA exhibits diverse bioactivities,...

Model organisms research: The foundation for understanding, regulating, and engineering life

Model organisms refer to a class of non-human experimental systems that have been widely adopted across the life sciences to uncover fundamental principles of biology [1]. Their defining strengths,...

Phytochrome B and CIPK31 coordinate VOZ2-dependent gibberellic acid signaling in rice

Light and calcium signaling regulate gibberellic acid (GA) pathways, but their coordination mechanism remains unclear....

Neuroinflammation-targeted natural products for the therapy of Alzheimer’s disease

Alzheimer’s disease (AD) is increasingly recognized as a multifactorial disorder characterized by a self-reinforcing pathological network, which involves the interplay of amyloid-beta (Aβ) deposition,...

Postnatal deletion of ZIP9 leads to premature mortality and hippocampal-dependent cognitive decline with disrupted brain–gut–lipid homeostasis

Androgen decline during aging contributes to cognitive impairment; androgen supplementation can improve these conditions. The zinc transporter ZIP9 has been identified as a membrane androgen receptor;...

Foliar ZnO NPs trigger transcriptional rewiring of starch and hormone pathways to break the yield-quality trade-off in direct-seeded rice

Direct-seeded rice (DSR) faces a persistent trade-off between grain yield and cooking quality. Conventional zinc fertilization often fails to overcome this limitation due to inefficient translocation...

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