Recent research progress of plant-derived chlorogenic acid in cancer therapy: Anticancer mechanism and combination therapy
July 2026
Chlorogenic acid (CGA), a natural hydroxycinnamic phenolic acid, is widely found in coffee, Eucommia ulmoides leaves and potatoes. Numerous studies have highlighted that CGA exhibits diverse bioactivities,...
Neuroinflammation-targeted natural products for the therapy of Alzheimer’s disease
July 2026
Alzheimer’s disease (AD) is increasingly recognized as a multifactorial disorder characterized by a self-reinforcing pathological network, which involves the interplay of amyloid-beta (Aβ) deposition,...
Phytochrome B and CIPK31 coordinate VOZ2-dependent gibberellic acid signaling in rice
July 2026
Light and calcium signaling regulate gibberellic acid (GA) pathways, but their coordination mechanism remains unclear....
Model organisms research: The foundation for understanding, regulating, and engineering life
July 2026
Model organisms refer to a class of non-human experimental systems that have been widely adopted across the life sciences to uncover fundamental principles of biology [1]. Their defining strengths,...
Postnatal deletion of ZIP9 leads to premature mortality and hippocampal-dependent cognitive decline with disrupted brain–gut–lipid homeostasis
July 2026
Androgen decline during aging contributes to cognitive impairment; androgen supplementation can improve these conditions. The zinc transporter ZIP9 has been identified as a membrane androgen receptor;...
Plant synthetic biology: From modular design to artificial intelligence-driven engineering
July 2026
Plant synthetic biology is emerging as a transformative approach to reprogram plants into programmable, sustainable production systems. Unlike traditional genetic engineering, which relies on trial-and-error...
Foliar ZnO NPs trigger transcriptional rewiring of starch and hormone pathways to break the yield-quality trade-off in direct-seeded rice
July 2026
Direct-seeded rice (DSR) faces a persistent trade-off between grain yield and cooking quality. Conventional zinc fertilization often fails to overcome this limitation due to inefficient translocation...
Model microorganisms: From cornerstones of modern discovery to big data-driven platforms
July 2026
For more than a century, model microorganisms have underpinned major biological explorations and facilitated pivotal advances in molecular genetics, biochemistry and biotechnology. These easy-to-manipulate...
Advances and perspectives in CRISPR-Cas9 for crop quality improvement
November 2026
Crops are the primary source of food for humans, providing essential nutrients such as carbohydrates and proteins. With economic development and rising living standards, demand for high-quality crops...
Nicotiana benthamiana: from model plant to biofactory chassis
July 2026
Nicotiana benthamiana has become a leading transient expression host for plant molecular farming, supporting the production of recombinant proteins, vaccine antigens, therapeutic antibodies and specialised...
The migratory locust (Locusta migratoria): A large-sized genome model for modern biology
July 2026
The migratory locust has long served as a model organism for insect morphology, behavior, physiology, and neurobiology. However, its wide application in modern biology has been limited by the lack of...