Model organisms research: The foundation for understanding, regulating, and engineering life
July 2026
Model organisms refer to a class of non-human experimental systems that have been widely adopted across the life sciences to uncover fundamental principles of biology [1]. Their defining strengths,...
Recent research progress of plant-derived chlorogenic acid in cancer therapy: Anticancer mechanism and combination therapy
July 2026
Chlorogenic acid (CGA), a natural hydroxycinnamic phenolic acid, is widely found in coffee, Eucommia ulmoides leaves and potatoes. Numerous studies have highlighted that CGA exhibits diverse bioactivities,...
Phytochrome B and CIPK31 coordinate VOZ2-dependent gibberellic acid signaling in rice
July 2026
Light and calcium signaling regulate gibberellic acid (GA) pathways, but their coordination mechanism remains unclear....
Foliar ZnO NPs trigger transcriptional rewiring of starch and hormone pathways to break the yield-quality trade-off in direct-seeded rice
July 2026
Direct-seeded rice (DSR) faces a persistent trade-off between grain yield and cooking quality. Conventional zinc fertilization often fails to overcome this limitation due to inefficient translocation...
Neuroinflammation-targeted natural products for the therapy of Alzheimer’s disease
July 2026
Alzheimer’s disease (AD) is increasingly recognized as a multifactorial disorder characterized by a self-reinforcing pathological network, which involves the interplay of amyloid-beta (Aβ) deposition,...
Postnatal deletion of ZIP9 leads to premature mortality and hippocampal-dependent cognitive decline with disrupted brain–gut–lipid homeostasis
July 2026
Androgen decline during aging contributes to cognitive impairment; androgen supplementation can improve these conditions. The zinc transporter ZIP9 has been identified as a membrane androgen receptor;...