AI and stroke rehabilitation: The past, present and future
December 2025
This article offers a comprehensive review of research progress in the field of artificial intelligence and stroke rehabilitation. It begins by exploring its historical development, which has progressed...
Regenerative rehabilitation: Mechanisms, clinical applications, and translational challenges
December 2025
Regenerative rehabilitation is an evolving discipline that strategically unites regenerative medicine with rehabilitation science to enhance functional recovery through synergistic biological and physical...
Natural and Synthetic Biomaterials, Structural Matrices-Based Wound Dressings: Key Properties, Material Correlation, and Adaptability
Available online 24 October 2025
The skin, the largest and fastest regenerating organ in the body, acts as a protective barrier against environmental threats. However, due to constant exposure, it is susceptible to various injuries....
Methylation-enriched Telomere Length Mediates the Association between Lead Exposure and Cognitive Function in an Aging Population
Available online 23 October 2025
This study investigated the mediating role of methylation-predicted telomere length (mTL) in the association between lead (Pb) exposure and cognitive decline among older adults, leveraging data from...
Green synthesis of AgNPs catalyzing free radical polymerization as wound dressing with an anti-bacterial effect
Available online 17 October 2025
The development of wound dressing materials remains a critical need, driven by the complexity of wound environments and the intricate nature of the healing process. One of the most common wound dressing...
Applications and Prospects of Artificial Intelligence in Wound Healing
Available online 15 October 2025
Wound healing is a critical aspect of clinical treatment, particularly in the management of complex wounds, including burns, diabetic foot ulcers (DFU). In recent years, artificial intelligence (AI)...
STEM CELL SECRETOMES FROM SURGICAL WASTE: A NOVEL APPROACH TO CANCER THERAPY – AN IN VITRO STUDY
Available online 26 September 2025
Cancer remains the second leading cause of mortality in India. Conventional chemotherapy is often limited by drug resistance, toxicity to healthy tissues, and promotion of metastasis, emphasizing the...
Cerium-based materials in burn wound healing: Development, mechanism and outlook
August 2025
Burn injuries are underestimated trauma in which moderate and severe burns are often associated with death. Early excision is the gold standard treatment for burn injuries to reduce the risk of infection,...
Surgical treatment of chronic ulcerative wounds of lower limbs in children with primary erythromelalgia: A case report and literature review
August 2025
To report a case of primary erythromelalgia with chronic lower limb ulcers treated surgically and to enhance understanding of the disease through a review of relevant literature....
ICF: The endpoint of rehabilitation assessment?
August 2025
The International Classification of Functioning, Disability and Health (ICF), developed by the World Health Organization, provides a biopsychosocial framework for describing health and health-related...
3D bioprinting for facial reconstruction: Advances and challenges
August 2025
Facial reconstruction presents significant challenges due to the complexity of soft and hard tissue integration. Traditional surgical approaches, including autografts and alloplastic implants, often...
Adipose-derived regenerative cells (ADRCs) in regenerative medicine: Current advances and future directions
August 2025
Adipose-derived regenerative cells (ADRCs) have emerged as a transformative tool in regenerative medicine, offering multifaceted therapeutic potential due to their accessibility, immunocompatibility,...
Development and validation of the second-modified nutrition risk screening 2002 for burn patients
August 2025
To develop the second-modified nutrition risk screening 2002 and evaluate its reliability and validity....
Research advances in purification, expression, and function of fibroblast growth factor 9
August 2025
The fibroblast growth factor (FGF) superfamily comprises 23 structurally related members that play pivotal roles in a wide range of biological and pathophysiological processes. These heparin-binding...
The global, regional, and national burden of oral disorders in 204 countries and territories, 1990–2021, and projections to 2050: A systematic analysis for the Global Burden of Disease Study 2021
August 2025
Oral disorders are among the most prevalent health conditions globally. This study aimed to systematically analyze the global, regional, and national burden of oral disorders between 1990 and 2021,...
Clinical application of Chambo tilapia fish skin xenograft for skin tissue regeneration: A case report in a partial-thickness burns pediatric patient
August 2025
WHO reports that burns account for more than 180,000 deaths annually with the majority of cases coming from low and middle-income countries due to limited resources in the management of burns. Currently,...
A free jigsaw puzzle perforator flap for repairing complicated wounds on extremities
April 2025
The single stage reconstruction of complicated wounds on extremities remains difficult due to the extensive skin and soft tissue defects, multiplanar defects requiring three-dimensional repair and functional...
Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: Findings from the Global Burden of Disease Study 2021
April 2025
Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...
Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials
April 2025
This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....
The role of systemic inflammatory response, hypermetabolism, and wound treatment and repair in hypernatremia of severely burned patients
April 2025
Hypernatremia represents a critical complication in patients with severe burns. This study aims to further investigate the etiology, clinical features, and therapeutic strategies for hypernatremia in...
Individualized therapy for wounds: Cases study and review
April 2025
This article reports two rare cases and reviews relevant literature to outline distinctive diagnostic and therapeutic approaches, aiming to provide a reference for colleagues in managing similar wounds....
Regenerative medicine in plastic surgery: The role of stem cells and bioprinting
April 2025
Regenerative medicine is revolutionizing plastic surgery, offering novel approaches to reconstructive and aesthetic challenges through the use of stem cells and bioprinting technologies. Stem cells,...
YOLOv7-PSA, an intelligent detection model, is designed for assessing the severity of skin burns
April 2025
We have developed an intelligent burn severity detection model called YOLOv7-PSA based on deep learning techniques and verified its efficiency and accuracy in assessing the severity of burn injuries....
The quest for the perfect healing of human skin wounds: Promising models
April 2025
Human skin is a compound organ performing essential functions in direct environmental contact. An orchestrated set of complex biological processes sustained by intricate molecular interactions leads...
Skin microecology and skin barrier repair, wound healing and appendage regeneration
January 2025
Skin is one of the barriers for organisms to resist the stimulation of the external environment. Hundreds of millions of microorganisms are implanted on the skin surface, and skin microorganisms are...