Thirty Years of Translational Research: A Personal Perspective on Gene-Transferred Porcine Skin Development
Available online 8 August 2026
This perspective recounts a three-decade journey of developing gene-transferred porcine skin for burn wound coverage—from a chance encounter at a research symposium in 1997 to a nationally registered...
Associations among umbilical midline diastasis severity, abdominal wall function, and quality of life in postpartum women with diastasis recti abdominis
Available online 7 August 2026
Obstetric diastasis recti abdominis (DRA), a common postpartum public health issue, often has its effects on maternal function and quality of life underestimated. Clarifying the correlation between...
From transient gene-transferred porcine skin to multigene-edited xenografts: Translational evolution of xenogeneic skin transplantation.
Available online 7 August 2026
Extensive burns and complex acute or chronic wounds continue to expose a persistent mismatch between the demand for biological wound coverage and the limited availability of autologous and allogeneic...
Initiative proposal for the establishment of a research consortium on skin xenotransplantation
Available online 6 August 2026
Skin xenotransplantation offers a promising solution to the critical shortage of skin donors for extensive burns and complex wounds, yet its clinical translation remains hindered by fragmented research,...
Advanced functional biobased materials for stem cell-mediated regenerative therapy
Available online 24 July 2026
Understanding and overcoming the limitations of cell survival, immune-mediated rejection, unpredictable cell differentiation, and poor host integration through stem cell-mediated regenerative therapy...
Electrospun nanofiber scaffolds for myocardial repair: Mechanistic design, preclinical advances, and translational perspectives
Available online 22 July 2026
Myocardial infarction (MI) remains a leading cause of global mortality and is characterized by irreversible cardiomyocyte loss, electrical uncoupling, fibrotic remodeling, and progressive ventricular...
Macroscopic complete safe surgical resection of a large plexiform neurofibroma of the back： Narrative literature review and case report
Available online 11 July 2026
Neurofibromatosis type 1 (NF1) is one of the most prevalent genetic disorders in humans, with plexiform neurofibromas (PN) affecting approximately 30% of individuals diagnosed with NF1. Surgical resection...
The application of adipose component transplantation in facial rejuvenation: A review and case report
Available online 11 July 2026
Facial rejuvenation is a hot topic in the field of plastic surgery. Autologous fat grafting has become an important method for facial rejuvenation due to its unique advantages, including good biocompatibility,...
Vital pulp therapy: A three-year clinical case series on regenerative potential and adhesive restoration strategies
June 2026
Vital pulp therapy (VPT) aims to preserve the vitality and regenerative potential of the dental pulp after carious or mechanical exposure. The introduction of hydraulic calcium silicate cements has...
Chinese expert consensus on Super-tension-reduction suture (Extra-tension-reduction suture) for surgical wounds (version 2025)
June 2026
Super-tension-reduction suture (STRS), also named extra-tension-reduction suture, refers to a suture technique maintaining the skin closed in a state of zero tension or even negative tension for a relatively...
Anchoring design of auricular cartilage silicone rhinoplasty
June 2026
Dorsal augmentation rhinoplasty using silicone implants combined with tip plasty using autologous cartilage is widely performed in Asian populations. Despite the advantages of silicone implants, including...
The evolution and current situation of regulations of China’s stem cell industry
June 2026
Stem cells and regenerative medicine represent one of the most revolutionary frontiers in life sciences, holding transformative potential for treating refractory diseases and improving public health....
Preparation of Yoda1@chitosan controlled release microspheres and their effects on bone injury repair at high-altitude
June 2026
The hypoxic and hypobaric conditions of high-altitude environments significantly impair osteogenesis and angiogenesis, leading to delayed bone healing and posing clinical challenges. In this study,...
Application of small and shallow external suture in facial aesthetic suturing
June 2026
To improve the external suture method in order to enhance the quality of wound healing and reduce scar formation....
Orthopedic applications of inorganic nanomaterials particularly in osteomyelitis
June 2026
The clinical management of osteomyelitis is significantly compromised by the increasing prevalence of antibiotic-resistant bacteria and biofilm-associated infections that evade conventional therapies....
Progress on self-aid and buddy-aid skills for field care of combat mental injury
June 2026
In modern warfare, combat mental injuries are highly prevalent. Field care of combat mental injuries is a vital issue of military health service, which may affect the outcome of war in the future. Therefore,...
Associations between awake-state cerebral hemodynamic activity and sleep quality: A longitudinal fNIRS study in young adults and implications for rehabilitation
June 2026
Poor sleep quality is a significant public health challenge, particularly among young adults, and can impede recovery and rehabilitation. However, there is a lack of objective, field-deployable neurophysiological...
The efficacy and safety of analgesia and sedation assisted dressing change (ASAD) in non-ICU wards: A randomized controlled trial
June 2026
Burn and trauma patients often suffer from pain, especially when dressing changes. Analgesia for ICU intubated or tracheotomised patients is generally well managed, whereas analgesia and sedation assisted...
Proteotoxic stress in stem cell therapies: The overlooked roles of senescence, EV cargo, and SOD1
Available online 9 June 2026
The rapid clinical expansion of therapies based on stem cells and cell-free extracellular vesicles (EVs) has outpaced the development of rigorous quality control standards. Current Good Manufacturing...
Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside
Available online 7 June 2026
Complex wounds remain a substantial clinical burden, despite advances in surgical reconstruction and biomaterial-based therapies. Adult stem cell strategies for skin repair have attracted wide interest,...
Fibroblast phenotypic plasticity: molecular mechanisms, context-dependent regulation, and clinical translation challenges— A comprehensive review
Available online 6 June 2026
Over the past century, fibroblasts were long regarded as homogeneous, passive connective-tissue cells, with their remarkable functional diversity and phenotypic plasticity largely overlooked. The rapid...
Functionalized BLGFs/ODEX hydrogel scaffold incorporating Oreochromis lidole skin collagen for bone tissue regeneration
Available online 6 June 2026
Bones provide support to the body and protect vital internal organs. Bones have the capacity to repair minor defects, but this ability is substantially impaired in large defects. Mineralization, which...
An HMMR-derived SHBG genetic score predicts lower type 2 diabetes risk
Available online 3 June 2026
Circulating sex hormone–binding globulin (SHBG) is associated with insulin resistance and cardiometabolic disease, yet causality, sex differences and genetic determinants remain unclear....
NSAIDs in paediatric burn injury: Mechanistic insights and clinical implications for inflammation and wound healing
Available online 30 May 2026
Burn injuries in children trigger a profound inflammatory response characterised by rapid release of damage-associated molecular patterns (DAMPs), cytokine elevation, neutrophil activation, and, in...