Vital pulp therapy: A three-year clinical case series on regenerative potential and adhesive restoration strategies
June 2026
Vital pulp therapy (VPT) aims to preserve the vitality and regenerative potential of the dental pulp after carious or mechanical exposure. The introduction of hydraulic calcium silicate cements has...
Chinese expert consensus on Super-tension-reduction suture (Extra-tension-reduction suture) for surgical wounds (version 2025)
June 2026
Super-tension-reduction suture (STRS), also named extra-tension-reduction suture, refers to a suture technique maintaining the skin closed in a state of zero tension or even negative tension for a relatively...
Anchoring design of auricular cartilage silicone rhinoplasty
June 2026
Dorsal augmentation rhinoplasty using silicone implants combined with tip plasty using autologous cartilage is widely performed in Asian populations. Despite the advantages of silicone implants, including...
The evolution and current situation of regulations of China’s stem cell industry
June 2026
Stem cells and regenerative medicine represent one of the most revolutionary frontiers in life sciences, holding transformative potential for treating refractory diseases and improving public health....
Preparation of Yoda1@chitosan controlled release microspheres and their effects on bone injury repair at high-altitude
June 2026
The hypoxic and hypobaric conditions of high-altitude environments significantly impair osteogenesis and angiogenesis, leading to delayed bone healing and posing clinical challenges. In this study,...
Application of small and shallow external suture in facial aesthetic suturing
June 2026
To improve the external suture method in order to enhance the quality of wound healing and reduce scar formation....
Orthopedic applications of inorganic nanomaterials particularly in osteomyelitis
June 2026
The clinical management of osteomyelitis is significantly compromised by the increasing prevalence of antibiotic-resistant bacteria and biofilm-associated infections that evade conventional therapies....
Progress on self-aid and buddy-aid skills for field care of combat mental injury
June 2026
In modern warfare, combat mental injuries are highly prevalent. Field care of combat mental injuries is a vital issue of military health service, which may affect the outcome of war in the future. Therefore,...
Associations between awake-state cerebral hemodynamic activity and sleep quality: A longitudinal fNIRS study in young adults and implications for rehabilitation
June 2026
Poor sleep quality is a significant public health challenge, particularly among young adults, and can impede recovery and rehabilitation. However, there is a lack of objective, field-deployable neurophysiological...
The efficacy and safety of analgesia and sedation assisted dressing change (ASAD) in non-ICU wards: A randomized controlled trial
June 2026
Burn and trauma patients often suffer from pain, especially when dressing changes. Analgesia for ICU intubated or tracheotomised patients is generally well managed, whereas analgesia and sedation assisted...
Proteotoxic Stress in Stem Cell Therapies: The Overlooked Roles of Senescence, EV Cargo, and SOD1
Available online 9 June 2026
The rapid clinical expansion of therapies based on stem cells and cell-free extracellular vesicles (EVs) has outpaced the development of rigorous quality control standards. Current Good Manufacturing...
Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside
Available online 7 June 2026
Complex wounds remain a substantial clinical burden, despite advances in surgical reconstruction and biomaterial-based therapies. Adult stem cell strategies for skin repair have attracted wide interest,...
Fibroblast phenotypic plasticity: molecular mechanisms, context-dependent regulation, and clinical translation challenges— a comprehensive review
Available online 6 June 2026
Over the past century, fibroblasts were long regarded as homogeneous, passive connective-tissue cells, with their remarkable functional diversity and phenotypic plasticity largely overlooked. The rapid...
Functionalized BLGFs/ODEX hydrogel scaffold incorporating Oreochromis lidole skin collagen for bone tissue regeneration
Available online 6 June 2026
Bones provide support to the body and protect vital internal organs. Bones have the capacity to repair minor defects, but this ability is substantially impaired in large defects. Mineralization, which...
An HMMR-derived SHBG genetic score predicts lower type 2 diabetes risk
Available online 3 June 2026
Circulating sex hormone–binding globulin (SHBG) is associated with insulin resistance and cardiometabolic disease, yet causality, sex differences and genetic determinants remain unclear....
NSAIDs in paediatric burn injury: Mechanistic insights and clinical implications for inflammation and wound healing
Available online 30 May 2026
Burn injuries in children trigger a profound inflammatory response characterised by rapid release of damage-associated molecular patterns (DAMPs), cytokine elevation, neutrophil activation, and, in...
Retrospective Analysis of Hyperselective Neurectomy for Upper Limb Spasticity Under Wide Awake Local Anaesthesia No Tourniquet (WALANT)
Available online 23 May 2026
Upper-limb spasticity resulting from stroke, traumatic brain injury (TBI), or cerebral palsy (CP) causes deformity and functional impairment. Hyperselective neurectomy (HSN) reduces spasticity by partial...
Frailty-specific dose-response relationships between physical activity and all-cause mortality: Longitudinal observational study combining accelerometry data
Available online 20 May 2026
Physical activity (PA) is inversely associated with all-cause mortality, yet how frailty status shapes the accumulation and saturation of this benefit remains unclear. This study aimed to assess frailty-specific...
Advances in hypertrophic scar animal model research: A multidimensional analysis from traditional models to emerging technologies
March 2026
Hypertrophic scar (HS) results from abnormal healing with excessive collagen and fibroblast activity, leading to cosmetic and functional problems and significantly impairing quality of life. Due to...
Challenges and opportunities for cardiac organoids: A comprehensive review
March 2026
Cardiac organoids, as 3D self-organizing models derived from pluripotent stem cells, can mimic the microstructure, cellular heterogeneity, and key functions of the human heart, providing a revolutionary...
Frontiers and hotspots in burn wound healing: A visualized bibliometric analysis
March 2026
Burns have caused an undeniable burden on medical resources and social economy, and burn wound healing is a long-term research hotspot....
Advancements in staging, grading and regenerative therapeutic approaches for osteoarthritis
March 2026
Osteoarthritis (OA) is a complex and heterogeneous degenerative joint disease, which demands a shift from generalized palliative care to precision medicine, necessitating accurate staging and grading...
Mechanical properties of hydrogel wound dressing in skin regeneration – a meta-analysis of in vivo studies
March 2026
This study quantitatively evaluated how the mechanical properties of hydrogel wound dressings influence in vivo wound healing outcomes, including wound closure, granulation tissue formation, collagen...
Family income and epilepsy prevalence in the United States: Insights from the National Health Interview Survey
March 2026
To investigate the association between family income and the prevalence of epilepsy in a representative sample of U.S. adults....