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ISSN: 2543-1064

Therapeutic potential of black seed oil in treating rheumatoid arthritis: Insights on biochemical and genetic analyses of inflammatory signaling transducer

Nigella sativa (Black seed) has been a longstanding component of traditional medicine. Rheumatoid arthritis, an autoimmune disorder targeting bone, cartilage, and synovial cells, leads to enduring joint...

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Etiological connections between initial COVID-19 and two rare infectious diseases

The origin of COVID-19 remains unclear despite extensive research. Theoretical models can simplify complex epigenetic landscapes by reducing vast methylation sites into manageable sets, revealing fundamental...

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Role of cognitive computing in enhancing innovative healthcare solutions

Cognitive computing represents a groundbreaking development in healthcare, encompassing technological platforms that emulate the human brain's functionality. While cloud computing offers on-demand internet...

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Influence of deproteinization and demineralization process sequences on the physicochemical and structural characteristics of chitin isolated from Deep-sea mud shrimp (Solenocera hextii)

Isolation of chitin from shrimp shell waste using chemical process is a well-adopted industrial practice due to its short process time and efficiency in removing both minerals and proteins from the...

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Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings

Tropical diseases present major health challenges in regions with limited resources, where access to advanced laboratory facilities is often scarce. This study explores the innovative techniques emerging...

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A brief history of urine examination - From ancient uroscopy to 21st century urinomics

The art of uroscopy (Greek ouron-urine and skopeo-examination), the visual inspection of urine, is as old as the history of mankind. It had seen its ups and downs, was praised and derided, but was ultimately...

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Unraveling ankylosing spondylitis: Exploring the genetic and immunological factors and latest treatment innovations

Ankylosing spondylitis (AS) is a chronic inflammatory arthritis primarily affecting the spine and sacroiliac joints. Gut microbiota significantly affects ankylosing spondylitis (AS) pathophysiology....

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Leveraging lean 4.0 technologies in healthcare: An exploration of its applications

Lean 4.0, a fusion of lean manufacturing and digital technologies, is a powerful tool for implementing Industry 4.0. Its widespread use across sectors is driven by its ability to eliminate waste, reduce...

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The effects of machine learning algorithms in magnetic resonance imaging (MRI), and biomarkers on early detection of Alzheimer's disease

Alzheimer's Disease (AD) is a disorder that worsens over time causing loss of memory and decline of cognitive functions. Current methods for diagnosis consist of neuroimaging scans, magnetic resonance...

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Chemical fingerprint of Centella Asiatica’s bioactive compounds in the ethanolic and aqueous extracts

Centella asiatica is a herbal plant that is widely used as medicine due to the benefit of its bioactive compounds such as rutin, kaempferol, quercetin, gallic acid, luteolin and catechin. Typically,...

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Biomarkers in immunology: Their impact on immune function and response

The immune system is a complex network of organs, tissues, and cells that plays a critical role in defending the body against life-threatening diseases such as infections, cancer, Alzheimer's, and Crohn's...

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A mini review: Role of novel biomarker for kidney disease of future study

In the world, kidney disease is most common cause of death. Primary care physicians must conduct appropriate diagnosis, and management in order to avoid detrimental consequences linked to death as well...

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Transforming early microbial detection: Investigating innovative biosensors for emerging infectious diseases

The recent global pandemic has highlighted an increase in the prevalence of communicable diseases caused by pathogens. The swift transmission of these diseases within a short timeframe presents a substantial...

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Procalcitonin and C-reactive protein as alternative salivary biomarkers in infection and inflammatory diseases detection and patient care: A scoping review

In ambulatory and hospital settings, inflammatory diseases stand a significant challenge for both patients and clinicians. These conditions, often serve as precursors to sepsis, necessitate effective...

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Genomic analysis identifies an incipient signature to forecast imatinib resistance before start of treatment in patients with chronic myeloid leukemia

The unprecedented success of tyrosine kinase inhibitor (TKI), imatinib, to induce remission in 86 % of chronic phase (CP) patients of chronic myeloid leukemia (CML) is undermined by drug resistance....

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Nanomedicine in cancer therapy: Advancing precision treatments

The progress made in the field of nanotechnology has resulted in the development of nanomedicine agents, which have demonstrated their efficacy as a promising clinical tool in the fight against different...

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Evaluation of toxicity and antioxidant activities of various crude extracts of leaves and stems of Zygophyllumsimplex

Zygophyllum simplex (Z. simplex) is a plant that has been used for a long time for the treatment of human diseases. Therefore, this present research study aims to prepare various plant extracts and...

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Application of Generative Adversarial Networks on RNASeq data to uncover COVID-19 severity biomarkers

The COVID-19 pandemic has highlighted the need for reliable biomarkers to predict disease severity and guide treatment strategies. However, the analysis of RNASeq data for biomarker discovery using...

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“MiRNA based target identification of TNFα gene in nephrotic syndrome”

Nephrotic syndrome (NS) can be caused by various underlying kidney conditions. In most cases, the exact cause of NS is unknown, although it may be related to the body's immune system malfunctioning....

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Taurine as a biomarker for aging: A new avenue for translational research

The physiologic and irreversible process of ageing is accompanied by a wide range of structural and functional shifts at multiple different levels. It is also suggested that variations in the blood...

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Development and applications of different types of green biosorbents for eliminations of hardness from water: A review on treatment, kinetics mechanism and future scope

The presence of toxic materials in water solutions, mainly harmful metals and metalloids, is a significant ecological and community issue. In village areas, hardness is major groundwater toxicity. Hardness,...

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Faecal microbial transplant

Faecal Microbial Transplantation (FMT), have been shown to be successfully managed along with a variety of gastrointestinal disorders, including Clostridioides difficile infection (CDI), inflammatory...

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CAR-T and nanotechnology: A comparative Perspective on autoimmune disease and cancer

Nanotechnology has emerged as a key transformative force in upgrading Chimeric Antigen Receptor T-cell (CAR-T) from generation to generation in cancer and autoimmune treatment. Nanotechnology-aided...

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Investigations of solid waste biosorbents for eliminations of total hardness from water: An experimental study of conversion of waste into valuable products

Hard water is a serious problem in the village areas. Alkaline hardness can cause eye pain, respiratory tract collapse, liver difficulties, and skin concerns. Human biological hardness after the extreme...

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Inflammation-induced cellular changes: Genetic mutations, oncogene impact, and novel glycoprotein biomarkers

Persistent inflammation can trigger the development of colorectal cancer, especially in patients with inflammatory bowel disease (IBD). The precise molecular mechanisms underlying this process are not...

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