Investigation of the effects of polyherbal formulations against the combination of a high-fat cafeteria diet along with exercise modalities
2024
The aim of the present study was to make a polyherbal formulation of three herbs that would offset the negative effects of the high-fat cafeteria diet on rats and the beneficial effects of exercise....
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Isolation and characterization of cytotoxic and antioxidant biomarkers from the aerial parts of Suaedaaegyptica
2024
Chronic disease is an irregular change inside or outside of the tissues and organs that results in accumulation, local damage, and inflammation or irritation. Suaeda aegyptiaca (S. aegyptiaca) is a...
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Faecal microbial transplant
2024
Faecal Microbial Transplantation (FMT), have been shown to be successfully managed along with a variety of gastrointestinal disorders, including Clostridioides difficile infection (CDI), inflammatory...
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Paper based molecularly imprinted SERS substrate for early detection of lysophosphatidic acid in ovarian cancer
2024
The current study is related to fabrication of point-of-care molecularly imprinted paper-based analytical devices, specifically related to ovarian cancer early stage detection. The task involves creating...
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A brief history of urine examination - From ancient uroscopy to 21st century urinomics
2024
The art of uroscopy (Greek ouron-urine and skopeo-examination), the visual inspection of urine, is as old as the history of mankind. It had seen its ups and downs, was praised and derided, but was ultimately...
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Patient-derived primary culture-based prognostic model to predict tumor recurrence in patients with glioma
2024
The prognosis for glioma patients remains grim despite aggressive treatment approaches. Current molecular profiles have limitations in predicting glioma recurrence, highlighting the need for new and...
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Transforming early microbial detection: Investigating innovative biosensors for emerging infectious diseases
2024
The recent global pandemic has highlighted an increase in the prevalence of communicable diseases caused by pathogens. The swift transmission of these diseases within a short timeframe presents a substantial...
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Matrix metalloproteinase 7 as a diagnostic biomarker of biliary atresia: A systematic review
2024
Biliary atresia (BA) is a disease of the intrahepatic or extrahepatic bile ducts with an unknown etiology. It presents in neonates with jaundice, clay-colored stool, and often hepatomegaly. Early diagnosis...
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Inflammation-induced cellular changes: Genetic mutations, oncogene impact, and novel glycoprotein biomarkers
2024
Persistent inflammation can trigger the development of colorectal cancer, especially in patients with inflammatory bowel disease (IBD). The precise molecular mechanisms underlying this process are not...
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Nanomedicine in cancer therapy: Advancing precision treatments
2024
The progress made in the field of nanotechnology has resulted in the development of nanomedicine agents, which have demonstrated their efficacy as a promising clinical tool in the fight against different...
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A systematic study on key Epigenetic modulators in post-stroke conditions
2024
A stroke is a medical emergency characterized by the sudden interruption of blood flow to the brain, leading to cell death from oxygen deprivation. As a leading cause of mortality and long-term disability...
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Leveraging lean 4.0 technologies in healthcare: An exploration of its applications
2024
Lean 4.0, a fusion of lean manufacturing and digital technologies, is a powerful tool for implementing Industry 4.0. Its widespread use across sectors is driven by its ability to eliminate waste, reduce...
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Role of cognitive computing in enhancing innovative healthcare solutions
2024
Cognitive computing represents a groundbreaking development in healthcare, encompassing technological platforms that emulate the human brain's functionality. While cloud computing offers on-demand internet...
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Comparison of urinary proteome in the first two days after mating in male rats
2024
To explore whether differences between male rats on the next day of mating and on the day of mating can be reflected by the urine proteome....
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The effects of machine learning algorithms in magnetic resonance imaging (MRI), and biomarkers on early detection of Alzheimer's disease
2024
Alzheimer's Disease (AD) is a disorder that worsens over time causing loss of memory and decline of cognitive functions. Current methods for diagnosis consist of neuroimaging scans, magnetic resonance...
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Exploring fucosylation in lung cancer: Mechanisms, diagnosis, and therapeutic strategies
2024
Lung cancer remains a global health crisis, responsible for significant morbidity and mortality. Late-stage diagnosis often limits treatment options and patient survival. Therefore, identifying reliable...
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Association of vitamin B12 and vitamin D in T2DM patients in north Indian population
2024
Diabetes mellitus, highly prevalent endocrine disorder and metformin is the most frequently recommended oral hypoglycemic agent (OHA)....
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Therapeutic potential of black seed oil in treating rheumatoid arthritis: Insights on biochemical and genetic analyses of inflammatory signaling transducer
2024
Nigella sativa (Black seed) has been a longstanding component of traditional medicine. Rheumatoid arthritis, an autoimmune disorder targeting bone, cartilage, and synovial cells, leads to enduring joint...
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Gene-Environment Interactions and Colorectal Cancer Risk: A Case-Control Study on Xenobiotic Metabolizing Enzyme Polymorphisms in the Jammu& Kashmir, India Population
Available online 19 October 2024
Cancer remains a significant global health concern, with colorectal cancer (CRC) showing a rising incidence, particularly among younger populations. Most CRC cases are linked to a complex interplay...
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World Urine Project
Available online 18 October 2024
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Isovalerylglycine and α-Ketobutyrate are novel biomarkers that discriminate clear cell renal cell carcinoma in biopsy specimens using two-dimensional magnetic resonance spectroscopy
2023
Tumor heterogeneity and lack of pre-operative diagnostic biomarkers are key topics in the field of renal cell carcinoma (RCC) identification. Clear cell RCC (ccRCC) is an aggressive cancer subtype which...
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Probing biological network in concurrent carcinomas and Type-2 diabetes for potential biomarker screening: An advanced computational paradigm
2023
Type-2 diabetes mellitus (T2DM), the predominant form of diabetes in adults, is a co-morbid condition that exacerbates the severity of many other diseases, including cardiovascular disease, obesity,...
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Potential consequences of screening of occupational silica dust exposed workers for early detection of silicosis/silico-tuberculosis using a novel biomarker, club cell protein-16, with possible intervention by repurposing metformin
2023
Earlier, a study conducted by the Indian Council of Medical Research – National Institute of Occupational Health (ICMR-NIOH), India, evidenced that CC16 may be used as a proxy marker and screening tool...
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Diagnostic performance of point-of-care ubiquitin carboxy-terminal Hydrolase-L1 assay in distinguishing imaging abnormalities in traumatic brain injury: A TRACK-TBI cohort study
2023
The use of UCH-L1 detection with point-of-care (POC) assay alone has not been characterized for clinical use. This study compares the accuracies of POC UCH-L1 and Neuron-Specific Enolase (NSE) Elecsys®...
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