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ISSN: 2096-6911
CN: 10-1634/R6
e-ISSN: 2772-686X

Polydeoxyribonucleotide: A promising skin anti-aging agent

Polydeoxyribonucleotide (PDRN) consists of DNA fragments with molecular weights ranging from 50 to 1 500 ​kDa, which are mainly extracted from the sperm cells of salmon trout or chum salmon. Many preclinical...

Longitudinal Melanonychia: How to Distinguish a Malignant Condition from a Benign One

Longitudinal melanonychia is not a rare clinical condition. It is mostly characterized by the presence of longitudinal, demarcated, and pigmented bands on the nail unit. The etiology is generally classified...

Eight-year follow-up on postoperative improvement protocol in extensive metoidioplasty transgenders: A case series

This study aimed to evaluate the long-term penile size among patients who underwent extensive metoidioplasty....

Lipedema: A common though often unrecognized condition

Lipedema is a chronic disorder primarily affecting women, characterized by abnormal fat deposition in the extremities, leading to pain, mobility issues, and psychological distress. These fat deposits...

Different administration routes of tranexamic acid in the treatment of melasma

Melasma is a prevalent and challenging skin condition that affects the face and causes distress in many patients and physicians. Tranexamic acid (TA) has been found to be effective for treating melasma...

Recent advances in scalable exosome production: Challenges and innovations

Exosomes, nanosized extracellular vesicles (30–150 ​nm), play a crucial role in intercellular communication and are promising biomarkers and therapeutic agents in oncology, neurodegenerative disorders,...

Dupuytren’s disease: A review

Dupuytren’s disease is a well-known benign fibroproliferative disorder that affects the palmar and digital fasciae of the hands. This spectrum includes nodule formation, cord formation, and flexion...

Classification of and the latest photoelectric therapy for epidermal nevi

An epidermal nevus (EN) is a common disease of various types, including verrucous EN, nevus sebaceous, inflammatory linear verrucous EN, Becker nevus, smooth muscle hamartoma, and nevus comedonicus....

Comprehensive pathogenesis and clinical therapy in striae distensae: An overview and current perspective

The pathogenesis of striae distensae (SD) is complicated and has not yet been fully elucidated. Hormonal changes, overstretched skin, and structural and functional changes in the skin may be crucial...

Diagnosis and Treatment of Axillary Web Syndrome: An Overview

Axillary web syndrome (AWS) is a self-limiting disease that can occur as an early or possibly late postoperative complication post-axillary surgery. This syndrome is characterized by the spread of the...

Advances in the study of epicanthus correction

Epicanthus is a half-moon-shaped skin fold diagonally or vertically distributed in front of the medial canthus. In mild cases, it affects aesthetics, whereas in severe cases, it may obscure the patient’s...

The “ARM” principle and practice: Preventing postoperative complications of circumcision

As one of the most commonly performed surgical procedures, circumcision may lead to complications. However, studies on preventing postoperative complications are scarce and still insufficient to draw...

Eyelid reconstruction methods: A 10-year review

In ophthalmological practice, eyelid reconstruction is often needed because of the presence of defects that arise after the excision of a tumor or after injuries. Various methods for reconstructing...

A treatment recommendation for trichoepithelioma: Thoughts on selection of treatment timing and method

In this report, we present the case of a 55-year-old woman with a 30-year history of multiple familial trichoepithelioma (MFT), with facial surface tumors that progressively worsened, causing ventilation...

Intralesional corticosteroid injections for infantile hemangioma

Infantile hemangiomas (IHs) are the most common benign soft-tissue tumors in infancy; about 10%–15% of them may result in various complications that require active management. The current first-line...

Management of Acute Achilles Tendon Rupture Using the Krackow and Tendon-Bundle Techniques

Acute Achilles tendon rupture is a severe injury of the lower extremities; however, optimal treatment options are not yet available. This study aimed to investigate the surgical method and clinical...

History and prospect of melanocytic nevus treatment: A bibliometric analysis

Melanocytic nevus is mainly treated by complete or partial removal. However, predicting the risk of malignant transformation of melanocytic nevi and which treatment patients should receive, surgical...

Acute traumatic extratemporal facial nerve injury: A 5-year review

Traumatic facial nerve injury is the second leading cause of facial paralysis, presenting significant challenges such as difficulties with eating, speaking, impaired vision, and loss of facial expression....

A review of complications of polyacrylamide hydrogel injection

Once a popular injectable filler, polyacrylamide hydrogel (PAAG) has been banned in China since 2006 due to its unclear safety and long-term complications. However, it is still being used worldwide...

Inflammatory Linear Verrucous Epidermal Nevus with a Novel CSPP1 Mutation: A Case Report and Review of the Literature

Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare type of epidermal nevus that occurs in infancy and develops along Blaschko's lines. Due to its rarity and clinical/histological similarities...

Complications Following Facial Thread-Lifting

Facial thread-lifting (FTL) is a minimally invasive facial rejuvenation technique. However, to date, no study has focused on the treatment of complications associated with FTL. The purpose of this study...

Inferior alveolar nerve injury after sagittal split osteotomy of the mandible: A literature review

Inferior alveolar nerve (IAN) injury is a serious potential complication of orthognathic surgery because the osteotomy cut-line during sagittal split osteotomy (SSO) of the mandible runs close to the...

Advances in photodynamic therapy for port-wine stain and our experience

Port-wine stain (PWS) is a congenital capillary malformation that occurs in 0.3%–0.5% of newborns. The pulsed dye laser is the current gold standard treatment for PWS; however, its efficacy is poor....

MEK inhibitors for the treatment of extracranial arteriovenous malformations

Arteriovenous malformations (AVMs) are serious congenital vascular anomalies in which the arteries connect directly with veins without capillaries. This condition will continue to worsen without proper...

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