Development and validation of a quality appraisal tool for case reports in traditional Chinese medicine using the Delphi method
June 2025
To develop a quality appraisal tool for case reports in traditional Chinese medicine (TCM) based on their characteristics....
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Correlation analysis between facial feature-based traditional Chinese medicine inspection of spirit classification and Beck Depression Inventory score
June 2025
To determine the correlation between traditional Chinese medicine (TCM) inspection of spirit classification and the severity grade of depression based on facial features, offering insights for intelligent...
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Lantana camara alleviating TNBS-induced ulcerative colitis in rats: regulating TNF-α/EGFR/STAT3/Bcl-2 signaling pathways
June 2025
To investigate the therapeutic potential and underlying mechanism of Lantana camara ethanolic extract (LCEE) in ulcerative colitis (UC)....
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Herbal remedies for Alzheimer’s disease: neuroprotective mechanisms and cognitive enhancement potential
June 2025
Alzheimer’s disease (AD) is a progressive neurodegenerative condition characterized by memory loss and cognitive decline. Current drugs offer limited benefits and often cause side effects. Recently,...
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Validating the pathogenic mechanism of chronic obstructive pulmonary disease induced by negative emotions via Mendelian randomization and traditional Chinese medicine theory of emotions
June 2025
We employed Mendelian randomization (MR) to test the traditional Chinese medicine (TCM) theory of emotional pathogenesis concept and explore the causal relationship between negative emotions and chronic...
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Development and validation of a nomogram model for predicting the risk of H-type hypertension with pulse diagram parameters
June 2025
To develop an onset risk prediction nomogram for patients with homocysteine-type (H-type) hypertension (HTH) based on pulse diagram parameters to assist early clinical prediction and diagnosis of H...
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Clinical research report on Chinese patent medicines and classic traditional Chinese medicine prescriptions (2023)
June 2025
Randomized controlled trials (RCTs) of Chinese patent medicines and classic traditional Chinese medicine prescriptions were systematically reviewed from both Chinese and English journals published in...
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Integrated plasma and synovial membrane lipidomic profiling revealing the therapeutic effects of moxibustion in collagen-induced arthritis rat models
June 2025
To reveal the therapeutic effects of moxibustion in collagen-induced arthritis (CIA) rat models using the combined analysis of plasma and synovial membrane lipidomic profiling and to enhance the understanding...
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Mechanism of electroacupuncture treating detrusor-bladder neck dyssynergia after suprasacral spinal cord injury by proteomics
June 2025
To elucidate the potential mechanisms of electroacupuncture (EA) in restoring detrusor-bladder neck dyssynergia (DBND) following suprasacral spinal cord injury (SSCI)....
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TCMHTI: a Transformer-based herb-target interaction prediction model for Qingfu Juanbi Decoction in rheumatoid arthritis
June 2025
To predict the potential targets of Qingfu Juanbi Decoction (青附蠲痹汤, QFJBD) in treating rheumatoid arthritis (RA) using an improved Transformer model and investigate the network pharmacological mechanisms...
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Construction and evaluation of a predictive model for the degree of coronary artery occlusion based on adaptive weighted multi-modal fusion of traditional Chinese and western medicine data
June 2025
To develop a non-invasive predictive model for coronary artery stenosis severity based on adaptive multi-modal integration of traditional Chinese and western medicine data....
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Evaluating the in vitro anti-diabetic activity of Bryonia dioica root extracts supported by molecular docking analysis
June 2025
To evaluate the in vitro anti-diabetic effects of Bryonia dioica roots extracts, including water-acetone extracts and their ethyl acetate and butanol fractions, and chloroform-methanol extracts....
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TCMLCM: an intelligent question-answering model for traditional Chinese medicine lung cancer based on the KG2TRAG method
March 2025
To improve the accuracy and professionalism of question-answering (QA) model in traditional Chinese medicine (TCM) lung cancer by integrating large language models with structured knowledge graphs using...
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Artificial intelligence in personalized cardiology treatment
March 2025
Cardiovascular diseases are the leading cause of death, requiring innovative approaches for prevention, diagnosis, and treatment. Personalized medicine customizes interventions according to individual...
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Research progress in digital auscultation: equipment and systems, characteristic parameters, and their application in diagnosis of pulmonary diseases and syndromes
March 2025
Traditional Chinese medicine (TCM) auscultation has a long history, and with advancements in equipment and analytical methods, the quantitative analysis of auscultation parameters has determined. However,...
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External application of traditional Chinese medicine in combination with three-step analgesic ladder therapy for cancer-induced bone pain: a systematic review and meta-analysis
March 2025
To systematically evaluate the overall efficacy of external application of traditional Chinese medicine (EA-TCM) in combination with oral three-step analgesic ladder therapy for patients suffering from...
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Multi-target inhibition property of Persicaria hydropiper phytochemicals against gram-positive and gram-negative bacteria via molecular docking, dynamics simulation, and ADMET analysis
March 2025
To evaluate the antibacterial potential of bioactive compounds from Persicaria hydropiper (L.) (P. hydropiper) against bacterial virulence proteins through molecular docking (MD) and experimental v...
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Bioinformatics-based analysis of autophagy-related genes and prediction of potential Chinese medicines in diabetic kidney disease
March 2025
To predict the autophagy-related pathogenesis and key diagnostic genes of diabetic kidney disease (DKD) through bioinformatics analysis, and to identify related Chinese medicines....
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Analysis of clinical characteristics and diagnostic prediction of Qi deficiency and blood stasis syndrome in acute ischemic stroke
March 2025
To explore the clinical characteristics and methods for syndrome differentiation prediction, as well as to construct a predictive model for Qi deficiency and blood stasis syndrome in patients with acute...
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From digits towards digitization: the past, present, and future of traditional Chinese medicine
March 2025
Digitization is the inevitable path for the natural development of traditional Chinese medicine (TCM) in the context of the Fourth Industrial Revolution. The goal of TCM digitization is to generate...
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Traditional Chinese medicine phenomics research on glycolipid metabolism disorder: a review
March 2025
Traditional Chinese medicine (TCM) has demonstrated unique advantages in the prevention and treatment of chronic diseases such as glycolipid metabolism disorder. However, its widespread application...
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Modulation of colonic DNA methyltransferase by mild moxibustion and electroacupuncture in ulcerative colitis TET2 knockout mice
March 2025
To investigate the mechanism of in alleviating colonic mucosal inflammation in ten-eleven translocation (TET) protein 2 gene knockout (TET2-/-) mice with ulcerative colitis (UC) by regulating DNA methyltransferase...
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Integrating proteomics and targeted metabolomics to reveal the material basis of liver-gallbladder damp-heat syndrome in chronic hepatitis B
December 2024
To elucidate the biological basis of liver-gallbladder damp-heat syndrome (LGDHS) within the framework of traditional Chinese medicine (TCM) as a complementary diagnostic and therapeutic approach in...
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