Optimization of cryopreservation of pathogenic microbial strains
December 2020
The preservation of pathogenic microbial strains is of great significance for basic research in microbiology and utilization of microbial resources. Appropriate preservation methods can maintain high...
Biosafety and biosecurity in the era of biotechnology: The Middle East region
December 2022
Biotechnology became a paradigm-shifting science among all subfields of biology. The benefits of biotechnology have reached many practical fields, whether human health, animal, and/or agricultural....
Biosafety laboratory risk assessment
September 2019
Biosafety laboratory risk assessment is a dynamic and systematic work. The scope of the assessment involves evaluation of pathogenic microbial hazards, experimental activities, facilities and equipment,...
Biosafety and biosecurity
March 2019
With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...
Design, establishment and accreditation of biosafety Level 3 laboratory using the Egyptian experience for sustainable high-containment capacity in national biological defence structure
June 2026
BSL-3 laboratories are crucial for global health security because they provide a basis for the research and diagnostics of new and known infectious agents. Yet few such facilities have been established,...
Human genome editing after the “CRISPR babies”: The double-pacing problem and collaborative governance
March 2023
How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge....
Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions
March 2019
Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...
Ethical framework on risk governance of synthetic biology
June 2023
Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may...
Integrated assessment of biosafety, biosecurity and cyber-biosecurity in clinical microbiology laboratories in Lubumbashi, Democratic Republic of the Congo
June 2026
Clinical microbiology laboratories in low-resource settings face increasing biological and digital risks, yet integrated evaluations of biosafety, biosecurity and cyberbiosecurity remain scarce in sub-Saharan...
Challenges and recent progress in the governance of biosecurity risks in the era of synthetic biology
June 2022
Considerable progress has been achieved in basic research and the biotechnological application of biological sciences in recent years. Synthetic biology integrates systems biology, engineering, computer...
A targeted vaccination strategy: Integrating vaccines into biosafety, biosecurity, and one health initiatives
March 2025
Vaccination has saved millions of lives and is regarded as one of modern medicine’s most important successes. Effective vaccination programs should be based on risk assessment that considers demographic...
Laboratory information management system for biosafety laboratory: Safety and efficiency
June 2021
Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work,...
Regulating synthetic biology and advanced genetic interventions: biosecurity frameworks, gene therapy oversight, stem-cell manufacturing risks and future policy directions
June 2026
Gene editing (CRISPR-Cas9, base and prime editing), viral-vector therapies (adeno-associated virus [AAV] and lentiviral systems) and engineered stem cell platforms (induced pluripotent stem cells and...
Mirror-image biology: perspectives and challenges
June 2026
Mirror-image biology is an emerging frontier in synthetic biology that uses chirally inverted biomolecules—D-proteins and L-nucleic acids—to construct orthogonal biological systems. Rapid advances in...
Patent-based analysis of biosafety trends in synthetic biology
March 2026
This study explored biosafety trends in synthetic biology through patent analysis. As an interdisciplinary field, synthetic biology brings innovation opportunities to society, but it is accompanied...
Bioinformatic assessment of the potential for harm to humans via horizontal gene transfer from the planned release of genetically modified mosquito vectors
June 2026
•The potential for mosquito to human Horizontal Gene (HGT) Transfer was investigated.•This contributed to a risk assessment for the release of genetically modified mosquitoes.•Analysis of human and...
Exploring the photodynamic antifungal efficacy and mechanism of red-emissive carbon dots
June 2026
These red-emissive carbon dots (CDs) can localize the mitochondria of the fungi and generate abundant singlet oxygen (1O2) under 525 nm LED irradiation, thereby disrupting the mitochondria of yeasts,...
Efficacy of commercial disinfectants Virkon®S and Microchem Plus against poliovirus
September 2025
The WHO Global Action Plan for Poliovirus Containment, 4th edition (GAPIV) describes the necessary conditions for the containment of poliovirus material in poliovirus-essential facilities (PEFs). PEF...
Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
June 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
Assessing decontamination practices at a medical microbiology research laboratory
December 2022
To our knowledge, this is the first study to conduct an objective assessment of the routine decontamination practices at a medical microbiology research laboratory (MRL) a year after a biosafety training...
Overview and prospects of food biosafety
December 2022
Biosafety issues have become a major threat to the health of humans, animals, and ecosystems worldwide. As problems with food production and the food supply chain have become of greater concern to consumers,...
Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET studies: An in silico approach
September 2023
•The binding affinity of Tecovirimat, Brincidofovir, Cidofovir against the mpox protein was examined in silico through molecular docking.•The binding affinity of such drugs/mAbs was compared with the...
Mathematical analysis and numerical simulation of campylobacteriosis dynamics: assessing the roles of house flies and contaminated food products as mechanical vectors
June 2026
Globally, food-borne campylobacteriosis is a major cause of bacterial gastroenteritis, disproportionately affecting impoverished areas. Inadequate sanitation infrastructure in these settings leads to...
Medical students’ mobile phones: hotspots for antimicrobial-resistant Gram-negative bacteria
March 2026
•Medical students’ mobile phones (MPs) can transmit resistant bacteria between various settings.•The high frequency of Gram-negative bacterial contaminants at our geographical area is striking.•Policies...