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ISSN: 2588-9338
CN: 10-1796/Q

Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions

Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...

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Origin and evolutionary analysis of the SARS-CoV-2 Omicron variant

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved rapidly into new variants throughout the pandemic. The Omicron variant has more than 50 mutations when compared with the...

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Challenges and recent progress in the governance of biosecurity risks in the era of synthetic biology

Considerable progress has been achieved in basic research and the biotechnological application of biological sciences in recent years. Synthetic biology integrates systems biology, engineering, computer...

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Biosafety and biosecurity

With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...

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Biosafety and biosecurity in the era of synthetic biology: Meeting the challenges in China and the U.S.

On July 26, 2019, the workshop “Biosafety and Biosecurity in the Era of Synthetic Biology: Meeting the Challenges in China and the U.S.”, co-hosted by Johns Hopkins Center for Health Security and Tianjin...

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Current status and future challenges of high-level biosafety laboratories in China

High-level biosafety laboratories are safe and secure platforms which integrate reliable containment, well-trained personnel, and specific biosafety manuals and practices to protect researchers from...

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Biosafety laboratory risk assessment

Biosafety laboratory risk assessment is a dynamic and systematic work. The scope of the assessment involves evaluation of pathogenic microbial hazards, experimental activities, facilities and equipment,...

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Optimization of cryopreservation of pathogenic microbial strains

The preservation of pathogenic microbial strains is of great significance for basic research in microbiology and utilization of microbial resources. Appropriate preservation methods can maintain high...

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A One Health strategy for emerging infectious diseases based on the COVID-19 outbreak

Coronavirus disease 2019 (COVID-19) is as an emerging infectious disease (EID) that has caused the worst public health catastrophe of the 21st century thus far. In terms of impact, the COVID-19 pandemic...

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A brief history of the development of infectious disease prevention, control, and biosafety programs in China

Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention,...

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Laboratory information management system for biosafety laboratory: Safety and efficiency

Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work,...

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Coronavirus disease 2019 epidemic prediction in Shanghai under the “dynamic zero-COVID policy” using time-dependent SEAIQR model

It’s urgently needed to assess the COVID-19 epidemic under the “dynamic zero-COVID policy” in China, which provides a scientific basis for evaluating the effectiveness of this strategy in COVID-19 control....

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High-containment facilities and the role they play in global health security

Biological threats, whether naturally occurring or accidentally or deliberately released, have the potential to endanger lives and disrupt economies worldwide. Thus, high-containment protective measures...

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“Mutation blacklist” and “mutation whitelist” of SARS-CoV-2

Over the past two years, scientists throughout the world have completed more than 6 million SARS-CoV-2 genome sequences. Today, the number of SARS-CoV-2 genomes exceeds the total number of all other...

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Recent developments and trends of automatic nucleic acid detection systems

Nucleic acid detection, widely used in clinical diagnosis, biological analysis, and environmental monitoring, is of great significance for disease diagnosis and basic research. With the outbreak of...

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Water sanitation and hygiene in Sub-Saharan Africa: Coverage, risks of diarrheal diseases, and urbanization

Sub-Saharan Africa (SSA) has a rapidly growing urban population, with water, sanitation, and hygiene (WASH) services representing the central needs for this population. Incidentally, this region has...

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Application of microneedle-based vaccines in biosecurity

Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats. Vaccination is one...

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Development of and prospects for the biological weapons convention

Biological weapons are used in wars to wound or kill people or animals and destroy crops with pathogenic microorganisms such as bacteria and viruses, as well as toxins and other biologically active...

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Bibliometric analysis of global scientific research on COVID-19

Since the outbreak of coronavirus disease 2019 (COVID-19), a large number of COVID-19-related reports have been published in journals or submitted to preprint platforms. In this study, we search the...

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Biosafety and biosecurity law in Thailand: From legislation to practice

Thailand has continuously established biosafety and security laws since 1932. The present law, the Pathogens and Animal Toxins Act 2015, was established for the controlled production, possession, sales,...

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Heat inactivation of the severe acute respiratory syndrome coronavirus 2

Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2...

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Public awareness, participation and attitude toward the national biosafety framework and genetically modified organisms in Ghana

Public engagement in the development, promotion, and utilization of innovation is an important part of any biosafety decision-making process. Under the Cartagena Protocol on Biosafety, the public is...

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Assessment of biosafety implementation in clinical diagnostic laboratories in Pakistan during the COVID-19 pandemic

Laboratory diagnostic capacity is crucial for an optimal national response to a public health emergency such as the COVID-19 pandemic. Preventing laboratory-acquired infections and the loss of critical...

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Pakistan’s experience with risk assessment training and implementation of concepts from the 4th edition of the WHO laboratory biosafety manual

The cyclical process of hazard identification, risk assessment, risk mitigation, and review is a key step in developing a biorisk management (BRM) system. This paper describes how this process was initiated...

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Wildlife-borne microorganisms and strategies to prevent and control emerging infectious diseases

China is one of the countries with the richest wildlife population. The large variety of widely distributed species act as natural or susceptible hosts for numerous infectious diseases. It is estimated...

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