A narrative review for antibacterials design and modification targeting outer membrane against Gram-negative bacteria
Available online 1 February 2026
With the increasing prevalence of refractory multidrug-resistant Gram-negative bacterial infections, the development of novel antibacterials targeting Gram-negative pathogens has become an urgent priority....
Centennial African swine fever: A comprehensive overview
Available online 18 January 2026
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and often fatal disease that affects domestic pigs and wild boars. Since its initial identification in Kenya...
Zoonotic diseases (zoonoses): definitions, classifications, hazards, and prevention strategies
Available online 17 January 2026
Zoonotic diseases, also known as zoonoses, are infectious diseases that can be transmitted between humans and animals, including livestock, wildlife, and companion animals. These diseases have become...
Microbiota and metabolic perturbations in bull semen: links to heat stress-induced quality decline
Available online 15 January 2026
Heat stress (HS) poses a major environmental issue that negatively impacts the reproductive efficiency of bulls. However, the complex interactions among HS-induced declines in semen quality, sperm metabolism,...
A multidimensional analysis of the pathogenesis of endometritis in dairy cows: A review
Available online 13 January 2026
Bovine endometritis is a major reproductive disease in postpartum dairy cows that significantly undermines herd productivity and the long-term economic sustainability of dairy operations globally. This...
Evaluation of the immune protective efficacy afforded by a telomerase interacting protein OTU in Eimeria tenella
Available online 12 January 2026
Chicken coccidiosis threatens the development of the poultry industry. The protective antigen genes applied to genetically engineered vaccines against Eimeria tenella (E. tenella) include TA4, SO7,...
Mogroside V inhibits the tunicamycin-induced endoplasmic reticulum stress in Caco-2 cells
Available online 12 January 2026
Endoplasmic reticulum stress (ERS) is a key driver of intestinal epithelial barrier dysfunction and inflammation, pathological features implicated in gastrointestinal disorders. Mogroside V (MV), a...
Intestinal microbiota dysbiosis in bovine mastitis: Its role and strategies for prevention and control targeting intestinal microbiota
Available online 3 January 2026
Mastitis in dairy cattle persists as a significant global challenge, imposing substantial economic losses and compromising animal welfare. Conventional antibiotic-based protocols remain clinically effective...
The effects of serotonin (5-hydroxytryptamine) on histone acetylation in early porcine embryos
December 2025
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter with emerging roles in mammalian embryonic development. However, its epigenetic effects on early porcine embryos remain poorly understood....
Current review for biological control of six common environmental mycotoxins
December 2025
Aflatoxin B1 (AFB1), zearalenone (ZEN), deoxynivalenol (DON), T-2 toxin (T-2), fumonisin B1 (FB1) and ochratoxin A (OTA) are the 6 most common environmental mycotoxins that are widely present in food...
The impaired hepatic PNPLA2-PPARα/δ signaling pathway is associated with lipid accumulation and inflammation in dairy cows with fatty liver
December 2025
Hepatic triacylglycerol (TAG) metabolic dysregulation, characterized by concurrent enhancement of synthesis and attenuation of degradation, is fundamental to the pathogenesis of fatty liver in dairy...
Genetic evolutionary dynamics and interspecies transmission risk of H9N2 subtype of avian influenza viruses
December 2025
Nature: A novel molecular mechanism of animal coronavirus infection mediated by the ACE2 receptor
December 2025
Role of parasite extracellular vesicles/exosomes in the interaction between hosts and virus-infected flagellate protozoa: Progress and prospects
December 2025
Parasite extracellular vesicles/exosomes (EVs/exos) are an emerging field in parasitology, sharing many commonalities with cell-derived EVs. Parasite EVs/exos have been recognized as mediators in parasite-parasite...
The effect of rumen fungal flora in the susceptibility of subacute ruminal acidosis in dairy goats
December 2025
Subacute rumen acidosis (SARA) is a condition commonly observed in high-yielding dairy cows, typically resulting from prolonged feeding of high-concentration diets (HCD). However, differences exist...
Critical role of cellular microRNAs in virus infection: Decades of progress
December 2025
MicroRNAs, or miRNAs, play a critical role in the complex interplay between viruses and their host organisms during viral infections. Over the past several decades, investigations into the functions...
Prevention of Clostridium perfringens induced chicken necrotic enteritis by probiotics: A review
December 2025
Necrotic enteritis (NE), predominantly affecting poultry with significant disorder, is mainly caused by bacterial pathogen Clostridium perfringens. The restriction of growth enhancers based on animal...
Promising strategies for accelerating the eradication of avian leukosis in China
December 2025
The national breeding and disease eradication programs in China are crucial for the healthy and sustainable development of the poultry industry. Among them, avian leukosis virus, the causative agent...
Probiotics for mitigating diarrhea in yak calves: Mechanisms, efficacy, and future perspectives
Available online 25 December 2025
Yak calves are a vital economic asset within high-altitude pastoral ecosystems; however, diarrhea continues to pose a significant threat to their health and growth, leading to substantial financial...
Recent advances on herpesvirus unique long protein 41
Available online 11 December 2025
The unique long protein 41 (UL41), also known as the virion host shutoff protein, is a conserved and multifunctional component of herpesviruses, first identified in herpes simplex virus and later in...
Epidemiology, antimicrobial resistance, economic burden, and management approaches for staphylococcus aureus-associated bovine mastitis: a systematic review
Available online 6 December 2025
Bovine mastitis, an inflammatory condition of the mammary gland, represents a formidable challenge to the global dairy industry, causing substantial economic losses and posing significant public health...
First Detection of Parainfluenza Virus 5 in Sika Deer: Evidence for Cross-Species Transmission and Zoonotic Potential
Available online 28 November 2025
Parainfluenza virus 5 (PIV5), a member of the Paramyxoviridae family, is a widely distributed respiratory pathogen with a broad host range; however, infection in sika deer has not previously been reported....
Will avian influenza virus (H10N3) cause a major public health threat?
Available online 22 November 2025
Avian influenza viruses (AIVs) cause significant economic losses to the poultry industry and pose a persistent threat to public health due to their capacity for cross-species infection of mammals and...
Viola yedoensis Makiho alleviates LPS-induced oxidative stress and inflammatory injury by regulating Nrf2 and NF-κB/NLRP3 signaling pathways in broilers
Available online 20 November 2025
Viola yedoensis Makiho (VYM), a traditional Chinese herbal medicine with anti-inflammatory and antioxidative properties, was investigated for its effects on lipopolysaccharide (LPS)-induced liver damage...
Zoonotic diseases in low and middle-income countries (LMICs): Economic burden, challenges, strategies, and future directions
Available online 5 November 2025
More than 200 zoonotic diseases are known to affect humans, representing a significant share of both emerging and existing infectious diseases worldwide. These diseases pose a major global public health...