Staphylococcus aureus infection: pathogenesis, virulence, immune evasion, persistence, and therapeutic strategies
Available online 14 October 2026
Staphylococcus aureus can cause persistent or recurrent infection despite in vitro antimicrobial susceptibility in both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA),...
iPSCs induction from bovine mammary epithelial cells
Available online 14 October 2026
Previous efforts to establish bovine induced pluripotent stem cells (biPSCs) have predominantly utilized fibroblasts. Considering that reproduction-related diseases such as mastitis and endometritis...
Nanoparticle-Based Mucosal Vaccines for Animal Infectious Diseases: Delivery Strategies, Immune Mechanisms, and Veterinary Applications in Ruminants, Swine, and Poultry
Available online 12 October 2026
Many animal pathogens enter through the respiratory, gastrointestinal, or reproductive mucosa, where early replication and shedding can occur before systemic immunity controls disease. Injectable vaccines...
Advances in natural products targeting porcine epidemic diarrhea virus
Available online 1 October 2026
Porcine epidemic diarrhea virus (PEDV) remains a major threat to the global swine industry, causing severe enteric disease with high morbidity and mortality in piglets and resulting in substantial economic...
Combined application of carbon dots and miRNA-21–5p promotes the resistance of mice to Actinobacillus pleuropneumoniae infection by inhibiting macrophage pyroptosis
September 2026
Bacterial pneumonia constitutes a major threat to the healthy development of animal husbandry and public health security. The escalating prevalence of bacterial drug resistance has exacerbated challenges...
Multidimensional pathogenic mechanisms of bovine viral diarrhea virus: From cell invasion to immune evasion
September 2026
Bovine viral diarrhea virus (BVDV) is a significant economic pathogen capable of establishing persistent infections in cattle, posing a major challenge to global cattle industries. This review systematically...
Advances in antiviral agents: A concise review
September 2026
Emerging and re-emerging viral infections continue to pose serious threats to global health, agriculture, and ecosystems. The rise of drug-resistant strains highlights the pressing demand for innovative...
Mechanisms of transmission and pathogenesis of alphaviruses
September 2026
Alphavirus is a genus of single-stranded positive sense RNA viruses, which infect vertebrate animals (humans, horses, rodents etc.) and/or arthropods. Medically important alphaviruses are mainly transmitted...
Persistent and recurrent Staphylococcus aureus infection: Biofilms, antibiotic tolerance, protected lesion niches, and therapeutic strategies
September 2026
Staphylococcus aureus (S. aureus) causes acute invasive disease as well as persistent and recurrent infections involving skin and soft tissue, the bloodstream and endovascular structures, bone and joints,...
Zoonotic bacterial pathogens from a One Health perspective: Antimicrobial resistance, exposure pathways, and control priorities
September 2026
Zoonoses are commonly defined as infectious diseases transmitted naturally from non-human animals to humans, or between humans and vertebrate animals. For bacterial pathogens, that definition is only...
Epidemiology, antimicrobial resistance, economic burden and management approaches for Staphylococcus aureus-associated bovine mastitis: A systematic review
September 2026
Bovine mastitis, an inflammatory condition of the mammary gland, represents a formidable challenge to the global dairy industry, causing substantial economic losses and posing significant public health...
Evaluation of the immune protective efficacy afforded by a telomerase interacting protein OTU in Eimeria tenella
September 2026
Chicken coccidiosis threatens the development of the poultry industry. The protective antigen genes applied to genetically engineered vaccines against Eimeria tenella (E. tenella) include TA4, SO7,...
A multidimensional analysis of the pathogenesis of endometritis in dairy cows: A review
September 2026
Bovine endometritis is a major reproductive disease in postpartum dairy cows that significantly undermines herd productivity and the long-term economic sustainability of dairy operations globally. This...
Microbiota and metabolic perturbations in bull semen: Links to heat stress-induced quality decline
September 2026
Heat stress (HS) poses a major environmental issue that negatively impacts the reproductive efficiency of bulls. However, the complex interactions among HS-induced declines in semen quality, sperm metabolism,...
Mogroside V inhibits the tunicamycin-induced endoplasmic reticulum stress in Caco-2 cells
September 2026
Endoplasmic reticulum stress (ERS) is a key driver of intestinal epithelial barrier dysfunction and inflammation, pathological features implicated in gastrointestinal disorders. Mogroside V (MV), a...
Staphylococcus aureus and MRSA biofilms in persistent and device-related infections: immune evasion, antimicrobial tolerance, relapse, and therapeutic strategies
Available online 24 September 2026
Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), is a major cause of persistent, device-related, and deep-seated infections that are difficult to eradicate and may relapse after...
Amur tiger recovery in Northeast China: conservation gains and coexistence challenges
Available online 12 September 2026
MIF drives Japanese encephalitis virus-induced pyroptosis in dopaminergic neurons through NF-κB-dependent NLRP3 inflammasome activation
Available online 5 September 2026
Japanese encephalitis virus (JEV) infection triggers pyroptosis in dopaminergic neurons, contributing to their degeneration. Macrophage migration inhibitory factor (MIF) is upregulated following JEV...
RT-RPA combined with CRISPR/Cas12a one-tube dual mode for detection of Akabane virus
Available online 4 September 2026
Akabane virus (AKAV) is an arbovirus, transmitted through the bites of blood-sucking insects on susceptible ruminants, belonging to the order Bunyavirales, family Peribunyaviridae, genus Orthobunyavirus....
Development of safe, effective, and field-applicable Mycoplasma synoviae vaccines for poultry farms: A formidable challenge
Available online 4 September 2026
Mycoplasma synoviae is a primary pathogenic bacterium threatening global poultry production, which triggers multiple typical clinical manifestations including airsacculitis, upper respiratory inflammation,...
Research progress in animal infection and zoonotic aspects of Bundibugyo virus
Available online 12 August 2026
Bundibugyo virus (BDBV) causes hemorrhagic fever in humans with a case fatality rate of 25%–51%. In recent years, breakthrough progress has been made in animal infection studies. This review focuses...
Advances in rapid diagnostic technologies for animal diseases: Integrating targeted detection with multimodal early warning
Available online 11 August 2026
Early identification and point-of-care diagnosis of animal diseases are critical for interrupting pathogen transmission, reducing economic losses, and ensuring livestock production safety. Although...
Emerging zoonotic and One Health-relevant pathogens in water systems: Surveillance and detection approaches
Available online 10 August 2026
Wastewater-based epidemiology (WBE) and environmental surveillance have become important components of One Health strategies to monitor zoonotic and environmentally transmitted pathogens. Improvements...
Zoonotic viruses: From spillover to pandemic preparedness
Available online 7 August 2026
Prevalence and genetic characterization of zoonotic Anaplasma spp. in sheep keds (Melophagus ovinus) in Qinghai, China
Available online 22 July 2026
Melophagus ovinus (sheep keds) is a major ectoparasite and pathogen vector in the Qinghai-Tibet Plateau. To investigate the prevalence and genetic diversity of zoonotic Anaplasma spp. carried by M....