Antibacterial conductive self-healing hydrogel wound dressing with dual dynamic bonds promotes infected wound healing
December 2023
In clinical applications, there is a lack of wound dressings that combine efficient resistance to drug-resistant bacteria with good self-healing properties. In this study, a series of adhesive self-healing...
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Advances in orthodontic clear aligner materials
April 2023
Rapid technological improvements in biomaterials, computer-aided design (CAD) and manufacturing (CAM) have endorsed clear aligner therapy (CAT) as a mainstay of orthodontic treatment, and the materials...
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Developing natural polymers for skin wound healing
March 2024
Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They are frequently encountered in various creatures, including...
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Photo-curing 3D printing technique and its challenges
March 2020
In recent ten years, 3D printing technology has been developed rapidly. As an advanced technology, 3D printing has been used to fabricate complex and high-precision objects in many fields. 3D printing...
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Decellularized extracellular matrix scaffolds: Recent trends and emerging strategies in tissue engineering
April 2022
The application of scaffolding materials is believed to hold enormous potential for tissue regeneration. Despite the widespread application and rapid advance of several tissue-engineered scaffolds such...
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Bone grafts and biomaterials substitutes for bone defect repair: A review
December 2017
Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft...
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Systematic development of ionizable lipid nanoparticles for placental mRNA delivery using a design of experiments approach
April 2024
Ionizable lipid nanoparticles (LNPs) have gained attention as mRNA delivery platforms for vaccination against COVID-19 and for protein replacement therapies. LNPs enhance mRNA stability, circulation...
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AI-enabled organoids: Construction, analysis, and application
January 2024
Organoids, miniature and simplified in vitro model systems that mimic the structure and function of organs, have attracted considerable interest due to their promising applications in disease modeling,...
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A tough, antibacterial and antioxidant hydrogel dressing accelerates wound healing and suppresses hypertrophic scar formation in infected wounds
April 2024
Wound management is an important issue that places enormous pressure on the physical and mental health of patients, especially in cases of infection, where the increased inflammatory response could...
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An overview of filtration efficiency through the masks: Mechanisms of the aerosols penetration
January 2021
The masks have always been mentioned as an effective tool against environmental threats. They are considered as protective equipment to preserve the respiratory system against the non-desirable air...
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Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration
September 2023
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its non-invasiveness, painless and simple administration, controllable drug delivery, and diverse cargo loading...
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Peptide-based nanomaterials: Self-assembly, properties and applications
May 2022
Peptide-based materials that have diverse structures and functionalities are an important type of biomaterials. In former times, peptide-based nanomaterials with excellent stability were constructed...
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SERS sensing for cancer biomarker: Approaches and directions
April 2024
These days, cancer is thought to be more than just one illness, with several complex subtypes that require different screening approaches. These subtypes can be distinguished by the distinct markings...
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An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses
April 2024
Marrow niches in osteosarcoma (OS) are a specialized microenvironment that is essential for the maintenance and regulation of OS cells. However, existing animal xenograft models are plagued by variability,...
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Biological and bioinspired materials: Structure leading to functional and mechanical performance
December 2020
Nature has achieved materials with properties and mechanisms that go far beyond the current know-how of the engineering-materials industry. The remarkable efficiency of biological materials, such as...
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Wound microenvironment self-adaptive hydrogel with efficient angiogenesis for promoting diabetic wound healing
February 2023
Neovascularization is critical to improve the diabetic microenvironment, deliver abundant nutrients to the wound and promote wound closure. However, the excess of oxidative stress impedes the healing...
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Biomaterial scaffolds in maxillofacial bone tissue engineering: A review of recent advances
March 2024
Maxillofacial bone defects caused by congenital malformations, trauma, tumors, and inflammation can severely affect functions and aesthetics of maxillofacial region. Despite certain successful clinical...
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Antibiofilm and antithrombotic hydrogel coating based on superhydrophilic zwitterionic carboxymethyl chitosan for blood-contacting devices
April 2024
Blood-contacting devices must be designed to minimize the risk of bloodstream-associated infections, thrombosis, and intimal lesions caused by surface friction. However, achieving effective prevention...
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Cellulose-based composite scaffolds for bone tissue engineering and localized drug delivery
February 2023
Natural bone constitutes a complex and organized structure of organic and inorganic components with limited ability to regenerate and restore injured tissues, especially in large bone defects. To improve...
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Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments
February 2024
Regulating macrophage activation precisely is crucial in treating chronic inflammation in osteoarthritis (OA). However, the stable pro-inflammatory state and deep distribution of macrophages in vivo...
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Keratin - Based materials for biomedical applications
September 2020
Keratin constitutes the major component of the feather, hair, hooves, horns, and wool represents a group of biological material having high cysteine content (7–13%) as compared to other structural proteins....
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Reactive oxygen species (ROS)-mediated M1 macrophage-dependent nanomedicine remodels inflammatory microenvironment for osteoarthritis recession
March 2024
Osteoarthritis (OA) is a common chronic inflammatory disorder. Effective remodeling of inflammatory microenvironment in the joint is a promising strategy to prevent OA. However, current drugs remain...
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Embedded 3D bioprinting – An emerging strategy to fabricate biomimetic & large vascularized tissue constructs
February 2024
Three–dimensional bioprinting is an advanced tissue fabrication technique that allows printing complex structures with precise positioning of multiple cell types layer–by–layer. Compared to other bioprinting...
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Antibacterial metals and alloys for potential biomedical implants
August 2021
Metals and alloys, including stainless steel, titanium and its alloys, cobalt alloys, and other metals and alloys have been widely used clinically as implant materials, but implant-related infection...
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Tumor diagnosis using carbon-based quantum dots: Detection based on the hallmarks of cancer
March 2024
Carbon-based quantum dots (CQDs) have been shown to have promising application value in tumor diagnosis. Their use, however, is severely hindered by the complicated nature of the nanostructures in the...
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