Advances in fluorescence imaging of RNAs in living cells based on functional nucleic acid probes
March 2024
RNA is an essential biomolecule that determines and regulates numerous biological process in cells. The sensitive and specific imaging of the expression level, localization and dynamic change of RNAs...
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Dual-microRNA triggered and DNA-programmed nanomachine for subtype-based detection and tailored treatment of breast cancer cells
March 2024
Discriminative detection and precise therapy targeting specific subtypes of breast cancers are critical for improving the treatment efficacy and thereby improving the survival rates of patients. Herein,...
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Wearable Janus nanofiber membrane-based colorimetric sensors for directional transfer and analysis of sweat
March 2024
Wearable sweat sensors are promising for real-time personalized health monitoring in a noninvasive manner. However, how to improve the wearing comfort and accuracy affected by sweat accumulation and...
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The nature of PDMS affects the results of the immunoassays carried out in microfluidic channels
March 2024
Due to various physical or biochemical processes, the nature of polydimethylsiloxane (PDMS) could affect the sensitivity and accuracy of immunoassays performed in microfluidic channels. An appropriate...
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Electrochemical aptamer-based biosensing of glycan-conjugated targets
March 2024
As the most complex post-translational modification, glycosylation involves the covalent linking of glycan(s) to a biomolecule. The glycosylation of proteins, peptides, lipids, and nucleic acids results...
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