Therapeutic potential of natural products in stress granules: Underlying molecular mechanisms and future perspectives
February 2025
Stress granules (SGs) are non-membranous structures that form in response to various cellular stress conditions. Natural compounds, derived from plants, animals, microorganisms, and marine organisms,...
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The role of Ursolic acid, a pharmacologically active compound from Ocimum sanctum L. as a potential chemotherapeutic agent
February 2025
The global cancer burden is predicted to rise by 40 % around the year 2030. Cancer-related mortality is exacerbated by the fact that the disease is becoming increasingly resistant to standard treatments....
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Integrated lipidomics and computational analyses reveal cardiolipin dysregulation as a therapeutic target in bortezomib-induced peripheral neuropathy
February 2025
Multiple myeloma (MM), a common blood cancer driven by abnormal plasma cells, is frequently treated with bortezomib (BTZ), which often triggers peripheral neuropathy (BIPN). While mitochondrial dysfunction...
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Emerging trends and hot topics in the application of multi-omics in drug discovery: A bibliometric and visualized study
December 2024
The application of multi-omics in drug discovery is rapidly advancing, but its trends and hotspots have not been fully analyzed. By reviewing key achievements and research hotspots in this field, the...
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Advances in drug discovery based on network pharmacology and omics technology
December 2024
Drug discovery plays a crucial role in cancer treatment. Traditional drug discovery methods mainly rely on in vivo animal experiments and in vitro drug screening, which are not only costly but also...
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Advancing pharmaceutical research: A comprehensive review of cutting-edge tools and technologies
December 2024
This comprehensive review investigates the cutting-edge tools and technologies that are revolutionizing modern pharmaceutical research. We analyze the integration of artificial intelligence and machine...
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