Open problems for the preparation and quality control of Ac-225 radiopharmaceuticals
January 2026
The aim of this brief review is to analyze the persistent chemical and radiochemical hurdles that still hinder the development of clinically useful actinium-225 (225Ac) radiopharmaceuticals for alpha-targeted...
Myrtus communis ameliorates ionizing radiation-induced cardiopulmonary injury in rats: TROD-GROG-003 study
January 2026
Ionizing radiation (IR), widely used in diagnostic and therapeutic procedures, can damage vital organs such as the heart and lungs through oxidative stress. This study aims to assess the potential radioprotective...
Association of mean cardiac dose with model-predicted risk of radiation-induced pericarditis in breast cancer patients
January 2026
This study aimed to investigate the association between mean cardiac dose (MCD) and the model-predicted risk of radiation-induced pericarditis in breast cancer patients undergoing radiotherapy....
Accuracy study of deep learning-based synthetic CT images for adaptive radiotherapy of pelvic tumors
January 2026
To evaluate the accuracy of deep learning conversion of cone-beam computed tomography (CBCT) into synthetic CT (sCT) for adaptive pelvic radiotherapy and to inform clinical application....
The role of 131I in the treatment and management of thyroid cancer
January 2026
For individuals with thyroid cancer, the most common cause of mortality worldwide is recurrent, metastatic disease. Radioactive iodine (RAI) remains the cornerstone of treatment for these patients....
Stereotactic body radiation therapy enhances therapeutic efficacy of immune checkpoint inhibitors by promoting the releasing of interferon-γ and interleukin-2
January 2026
To explore whether stereotactic body radiation therapy (SBRT) could promote the release of serum interferon-γ (IFN-γ) and interleukin-2 (IL-2), as well as the prognostic value of IFN-γ in patients receiving...
Radiation dosimetry of [124I]-metaiodobenzylguanidine (mIBG) dynamic PET/CT in pediatric neuroblastoma through animal-to-human extrapolation with MCNPX code and OLINDA/EXM software
January 2026
Iodine-124 metaiodobenzylguanidine (mIBG) positron emission tomography (PET)/computed tomography (CT) is well-established for imaging and pre-therapeutic dosimetry in pediatric neuroblastoma. However,...
Dosimetric evaluation of the PASSAG polymer gel dosimeter improved with sucrose using MRI
January 2026
One of the main constraints of polymer gel dosimeters for use in clinical settings is the high toxicity of their compounds. PASSAG gel dosimeter provides excellent dosimetric properties and very low...
Radiopharmaceuticals for microbiome imaging: A narrative review of emerging approaches to mapping host–microbe interactions
January 2026
The human microbiome has immense effects on immunity, metabolism, and therapeutic response, but non-invasive in vivo visualization is underdeveloped. Radiopharmaceuticals, traditionally applied in oncology...
Analysis of set-up errors in daily kilovolt fan beam CT for rectal cancer treated with volumetric modulated arc therapy
January 2026
To analyze inter-fractional set-up errors in rectal cancer patients undergoing volumetric modulated arc therapy (VMAT) guided by daily kilovolt fan beam CT (kV-FBCT)....
Real-time motion compensation in cyberknife radiosurgery: Advances in fiducial marker tracking and clinical outcomes
January 2026
CyberKnife, a stereotactic radiosurgery (SRS) technique, delivers highly precise radiation beams to tumors. However, the patient motion, such as respiration and positional changes, can lead to tumor...
Comparative dosimetric analysis of hippocampal-sparing vs conventional craniospinal irradiation in central nervous system leukemia: A single-center study
January 2026
To evaluate dosimetric differences between hippocampal-sparing (HS) and conventional craniospinal irradiation (CSI) in central nervous system leukemia (CNSL) patients....
Relationship between coronary CTA morphological parameters, serum ApoA1, ApoB/ApoA1, and prognosis of patients with coronary heart disease
January 2026
To explore the relationship between coronary computed tomography angiography (CTA) morphological parameters, serum apolipoprotein A1 (ApoA1), the ratio of apolipoprotein B (ApoB) to ApoA1 (ApoB/ApoA1),...
Exploring radiation pneumonitis associated with immune checkpoint inhibitors: Insights from the FAERS pharmacovigilance database
January 2026
The combination of immunotherapy and radiotherapy has become an important strategy for treating thoracic tumors. However, both treatment modalities can cause adverse effects to lung tissue. Research...