Radioprotective effect of pyrogallol nanocomposite on radiation-induced toxicity in spleen and bone marrow of BALB/c mice
September 2026
Radiotherapy is a first-line treatment for cancer that utilizes high-energy ionizing radiation to eliminate cancer cells. However, its therapeutic efficacy is often limited by their toxicity to healthy...
Technetium-99m labelled fluoroquinolone-based radiotracers for infection imaging: A critical review
September 2026
Proper distinction between bacterial infection and sterile inflammation is one of the major issues in molecular imaging. Though radiolabelled leukocytes and [18F]fluorodeoxyglucose ([18F]FDG) have retained...
Clinical diagnosis and treatment of refractory neuro-ischemic diabetic foot ulcer: A case report
September 2026
Neuro-ischemic diabetic foot ulcers (DFUs) associated with advanced peripheral artery disease and severe neuropathy pose a considerable challenge for limb preservation, especially when repeated revascularization...
Cardiac function measurement: CMR versus CT imaging using various reconstruction matrices
September 2026
To evaluate the consistency of cardiac function measurements between cardiac magnetic resonance (CMR) and coronary computed tomography angiography (CCTA) across various reconstruction matrices and to...
Optimization of reaction conditions and process automation for [99mTc]Tc-PSMA-I&S preparation on a GAIA® synthesizer
July 2026
Radioguided surgery (RGS) using PSMA radioligands emerged as a valuable approach for the detection of metastatic lymph nodes in prostate cancer. [99mTc]Tc-PSMA-I&S is specifically designed for combined...
Theranostic applications of PSMA-targeted radiopharmaceuticals: From molecular design to clinical translation and emerging paradigms
July 2026
Theranostics is an innovative concept in nuclear medicine that combines molecular imaging with targeted radionuclide therapy. PSMA is the best-studied and most clinically utilized oncological theranostic...
MPI SPECT and GSPECT in type 2 diabetes mellitus patient: Combined perfusion and functional imaging for cardiovascular risk stratification
July 2026
Cardiovascular disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Early detection of subclinical coronary and myocardial injury is therefore essential...
Next‑generation theranostic radiopharmaceuticals: Integrating alpha emitters and nanocarriers for precision oncology
July 2026
Alpha-emitting radionuclides, characterized by high-linear energy transfer (LET) and short path length, are emerging as potent tools in targeted cancer therapy. When combined with advanced nanocarrier...
Activity-normalized survey-meter assessment around patients undergoing ⁹⁹ᵐTc-pertechnetate thyroid scintigraphy: Implications for radiation protection
July 2026
Patients undergoing diagnostic nuclear medicine procedures temporarily become sources of external radiation, potentially contributing to exposure of staff, accompanying persons, and other patients....
Convergence methodologies for PSMA-targeted radiotheranostics: A transformative blueprint for precision prostate cancer management
July 2026
PSMA-targeted radiotheranostics has become an important component of precision prostate cancer management, supported by recent clinical trials of ^177Lu-PSMA-617 and ^225Ac-PSMA ligands. Concurrently,...
Case report of systemic inflammatory response syndrome in refractory gout mimicking infective endocarditis: Diagnosis via PET–CT and successful treatment with firsekibart
July 2026
Severe gout can manifest as systemic inflammatory response syndrome (SIRS), closely mimicking infective endocarditis (IE) and presenting a diagnostic challenge, particularly in patients with complex...
Proteomics- and bioinformatics-based identification of regulators of radiosensitivity in lung cancer
July 2026
Radiotherapy resistance is a major challenge in lung cancer (LC) treatment, affecting patient outcomes. The protein networks underlying radiotherapy response remain incompletely understood....
The PSMA paradox: How biology, androgen signaling, and therapy sequencing shape Lu-177 efficacy
July 2026
Livoscan a deep learning framework with attention mechanisms for accurate liver fibrosis detection
July 2026
Liver fibrosis is a progressive disease that is progressive in nature and develops due to chronic liver injuries that can ultimately progress into cirrhosis and cancer of the liver if not detected early....
Research progress on precision prevention and treatment of prediabetes based on multi-omics-imaging-pharmacology synergistic mechanisms from an integrated Chinese and Western medicine perspective
July 2026
This paper reviews recent advances in the precise management of prediabetes, adopting an integrative perspective that synergizes multi-omics, radiomics, and pharmacological insights from both traditional...
Radioprotective effects of curcumin during radiotherapy: Critical evaluation of preclinical and clinical evidence
July 2026
Radiation therapy is a key treatment modality for cancer, effectively targeting malignant cells. However, the treatment is often associated with harmful side effects due to radiation-induced damage...
METTL3 inhibits FAO activity and promotes lipid accumulation to regulate the biological functions of gastric cancer through YTHDF2-dependent VLCAD mRNA degradation
July 2026
Chemoradioresistance is one of the main causes of treatment failure and recurrence of gastric cancer (GC). Metabolic reprogramming, especially the abnormal activation of fatty acid oxidation (FAO),...
Structural MRI reveals brain differences in asthmatic patients with and without atopic dermatitis
May 2026
Building on accumulating evidence that atopic inflammation and neuroimmune/neurocognitive processes may influence the central nervous system, we aimed to compare structural brain imaging features between...
Dose prediction of intensity-modulated radio therapy for brain tumors based on an improved deep learning framework
May 2026
Accurate calculation of dose distribution is a critical component in intensity-modulated radiation therapy (IMRT). The dose distribution exhibits significant variability across patients. To address...
Synergistic role of multi-omics analysis combined with multimodal imaging in precision diagnosis and treatment of thoracic and abdominal tumors
May 2026
Thoracic and abdominal tumors, such as lung, breast, liver, and colorectal cancers, are characterized by high incidence and mortality rates, posing a significant threat to global health. Traditional...
EAVS-TF: A bio-inspired spiking neural network for energy-efficient multimodal emotion recognition
May 2026
Accurate recognition of emotional states is critical for monitoring neuropsychiatric disorders, however, deploying such systems on battery-powered wearable devices necessitates exceptional energy efficiency....
Research on image segmentation of lightweight thyroid nodules
May 2026
This study aims to address the challenges inherent in thyroid nodule ultrasound image segmentation, such as excessive computational complexity, limited data availability, and the suboptimal segmentation...
GATA3 contributes to radiation-induced lung injury by regulating ESM1-mediated NF-κB signaling and inflammatory responses
May 2026
Radiation-induced lung injury (RILI) is damage to normal lung tissue caused by thoracic tumor radiotherapy (RT), but effective interventions are lacking and its molecular mechanisms remain unclear....
Anatomy as a guide: Using learned priors for precise organ segmentation
March 2026
Accurate segmentation of abdominal organs from Computed Tomography (CT) is essential for clinical tasks such as radiotherapy planning but is hindered by ambiguity at organ boundaries. Standard deep...
Integration of conventional MRI and diffusion-weighted imaging for differential diagnosis of high-grade gliomas and metastatic brain tumors
March 2026
Brain tumors, particularly high-grade gliomas (HGG) and solitary brain metastases (SBM), often present with overlapping clinical and imaging features, complicating accurate diagnosis and management....