Radioprotective effect of pyrogallol nanocomposite on radiation-induced toxicity in spleen and bone marrow of BALB/c mice
September 2026
Radiotherapy is a first-line treatment for cancer that utilizes high-energy ionizing radiation to eliminate cancer cells. However, its therapeutic efficacy is often limited by their toxicity to healthy...
Technetium-99m labelled fluoroquinolone-based radiotracers for infection imaging: A critical review
September 2026
Proper distinction between bacterial infection and sterile inflammation is one of the major issues in molecular imaging. Though radiolabelled leukocytes and [18F]fluorodeoxyglucose ([18F]FDG) have retained...
Clinical diagnosis and treatment of refractory neuro-ischemic diabetic foot ulcer: A case report
September 2026
Neuro-ischemic diabetic foot ulcers (DFUs) associated with advanced peripheral artery disease and severe neuropathy pose a considerable challenge for limb preservation, especially when repeated revascularization...
Cardiac function measurement: CMR versus CT imaging using various reconstruction matrices
September 2026
To evaluate the consistency of cardiac function measurements between cardiac magnetic resonance (CMR) and coronary computed tomography angiography (CCTA) across various reconstruction matrices and to...
Next-generation therapeutic strategies in prostate cancer: Integrating targeted therapy, radioligand therapy, and precision oncology
September 2026
Prostate cancer continues to present major clinical challenges, particularly in advanced and metastatic settings where therapeutic resistance and tumor heterogeneity limit the long-term efficacy of...
Diagnosis and comprehensive therapy for multiple primary lung cancer: A narrative review
September 2026
The increasing use of chest computed tomography (CT), positron emission tomography-computed tomography (PET-CT), and lung cancer screening has led to more frequent detection of multiple pulmonary lesions....
Parotid MRI for the evaluation of primary Sjögren's syndrome: A meta‑analysis
September 2026
This study aims to assess the diagnostic utility of parotid gland magnetic resonance imaging (MRI) in patients with primary Sjögren’s syndrome (pSS)....
A deep learning fusion model based on CT radiomics and EBUS for preoperative prediction of mediastinal lymph node metastasis in lung adenocarcinoma
September 2026
Preoperative prediction of mediastinal lymph node metastasis in lung adenocarcinoma is of great significance for clinical decision-making. Accurate assessment of mediastinal lymph node metastasis guides...
Prospects of artificial intelligence in multimodal integration of methylation and imaging features for precision cervical cancer screening
September 2026
Cervical cancer remains a major public health threat to women worldwide, and early screening is critical for reducing its incidence and mortality. Although human papillomavirus (HPV)-based screening...
The algorithmic isotope: artificial intelligence and the future of radiopharmaceutical medicine
September 2026
Nano-radiopharmaceuticals at the crossroads: A critical analysis of advances, limitations, and clinical trajectories in imaging and therapy
September 2026
Nano-radiopharmaceuticals have re-surfaced under the limelight of nuclear medicine at the intersection of nanotechnology, radiochemistry and theranostics. Even though there has been much preclinical...
Impact of catheter removal timing and an ultrasound/DSA-guided stratified management strategy on outcomes of difficult PICC removal in malignant tumor patients: A single-center retrospective study of 61 cases
September 2026
To evaluate the impact of catheter removal timing and an ultrasound/digital subtraction angiography (DSA)-guided stratified management strategy on outcomes in malignant tumor patients experiencing difficult...
Synergy of imaging modalities and omics profiling: Unlocking unmet clinical potentials of novel radiopharmaceuticals
September 2026
Radioprotective nanomedicines: New horizons in mitigating radiation-induced tissue injury
September 2026
Ionizing radiation remains indispensable in cancer therapy, diagnostics, and industrial and space applications, yet radiation-induced normal tissue injury continues to limit therapeutic efficacy and...
A novel applicator for beta radionuclide brachytherapy of skin cancer using 188Re source
September 2026
Brachytherapy (BT) is a useful modality for treating small, early-stage skin cancers. Beta-emitting sources have also been widely investigated due to their inherently steep dose fall-off, which helps...
Research progress on multimodal monitoring combined with biomarkers in critical care management strategies after neurointerventional surgery
September 2026
Neurointerventional techniques are core treatments for cerebrovascular diseases, yet postoperative complications, including ischemia-reperfusion injury, hyperperfusion syndrome, vasospasm, and delayed...
Optimization of reaction conditions and process automation for [99mTc]Tc-PSMA-I&S preparation on a GAIA® synthesizer
July 2026
Radioguided surgery (RGS) using PSMA radioligands emerged as a valuable approach for the detection of metastatic lymph nodes in prostate cancer. [99mTc]Tc-PSMA-I&S is specifically designed for combined...
Theranostic applications of PSMA-targeted radiopharmaceuticals: From molecular design to clinical translation and emerging paradigms
July 2026
Theranostics is an innovative concept in nuclear medicine that combines molecular imaging with targeted radionuclide therapy. PSMA is the best-studied and most clinically utilized oncological theranostic...
MPI SPECT and GSPECT in type 2 diabetes mellitus patient: Combined perfusion and functional imaging for cardiovascular risk stratification
July 2026
Cardiovascular disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Early detection of subclinical coronary and myocardial injury is therefore essential...
Next‑generation theranostic radiopharmaceuticals: Integrating alpha emitters and nanocarriers for precision oncology
July 2026
Alpha-emitting radionuclides, characterized by high-linear energy transfer (LET) and short path length, are emerging as potent tools in targeted cancer therapy. When combined with advanced nanocarrier...
Activity-normalized survey-meter assessment around patients undergoing ⁹⁹ᵐTc-pertechnetate thyroid scintigraphy: Implications for radiation protection
July 2026
Patients undergoing diagnostic nuclear medicine procedures temporarily become sources of external radiation, potentially contributing to exposure of staff, accompanying persons, and other patients....
Convergence methodologies for PSMA-targeted radiotheranostics: A transformative blueprint for precision prostate cancer management
July 2026
PSMA-targeted radiotheranostics has become an important component of precision prostate cancer management, supported by recent clinical trials of ^177Lu-PSMA-617 and ^225Ac-PSMA ligands. Concurrently,...
Case report of systemic inflammatory response syndrome in refractory gout mimicking infective endocarditis: Diagnosis via PET–CT and successful treatment with firsekibart
July 2026
Severe gout can manifest as systemic inflammatory response syndrome (SIRS), closely mimicking infective endocarditis (IE) and presenting a diagnostic challenge, particularly in patients with complex...
Proteomics- and bioinformatics-based identification of regulators of radiosensitivity in lung cancer
July 2026
Radiotherapy resistance is a major challenge in lung cancer (LC) treatment, affecting patient outcomes. The protein networks underlying radiotherapy response remain incompletely understood....