Livoscan a deep learning framework with attention mechanisms for accurate liver fibrosis detection
July 2026
Liver fibrosis is a progressive disease that is progressive in nature and develops due to chronic liver injuries that can ultimately progress into cirrhosis and cancer of the liver if not detected early....
Research progress on precision prevention and treatment of prediabetes based on multi-omics-imaging-pharmacology synergistic mechanisms from an integrated Chinese and Western medicine perspective
July 2026
This paper reviews recent advances in the precise management of prediabetes, adopting an integrative perspective that synergizes multi-omics, radiomics, and pharmacological insights from both traditional...
Radioprotective effects of curcumin during radiotherapy: Critical evaluation of preclinical and clinical evidence
July 2026
Radiation therapy is a key treatment modality for cancer, effectively targeting malignant cells. However, the treatment is often associated with harmful side effects due to radiation-induced damage...
METTL3 inhibits FAO activity and promotes lipid accumulation to regulate the biological functions of gastric cancer through YTHDF2-dependent VLCAD mRNA degradation
July 2026
Chemoradioresistance is one of the main causes of treatment failure and recurrence of gastric cancer (GC). Metabolic reprogramming, especially the abnormal activation of fatty acid oxidation (FAO),...
Structural MRI reveals brain differences in asthmatic patients with and without atopic dermatitis
May 2026
Building on accumulating evidence that atopic inflammation and neuroimmune/neurocognitive processes may influence the central nervous system, we aimed to compare structural brain imaging features between...
Dose prediction of intensity-modulated radio therapy for brain tumors based on an improved deep learning framework
May 2026
Accurate calculation of dose distribution is a critical component in intensity-modulated radiation therapy (IMRT). The dose distribution exhibits significant variability across patients. To address...
Synergistic role of multi-omics analysis combined with multimodal imaging in precision diagnosis and treatment of thoracic and abdominal tumors
May 2026
Thoracic and abdominal tumors, such as lung, breast, liver, and colorectal cancers, are characterized by high incidence and mortality rates, posing a significant threat to global health. Traditional...
EAVS-TF: A bio-inspired spiking neural network for energy-efficient multimodal emotion recognition
May 2026
Accurate recognition of emotional states is critical for monitoring neuropsychiatric disorders, however, deploying such systems on battery-powered wearable devices necessitates exceptional energy efficiency....
Research on image segmentation of lightweight thyroid nodules
May 2026
This study aims to address the challenges inherent in thyroid nodule ultrasound image segmentation, such as excessive computational complexity, limited data availability, and the suboptimal segmentation...
GATA3 contributes to radiation-induced lung injury by regulating ESM1-mediated NF-κB signaling and inflammatory responses
May 2026
Radiation-induced lung injury (RILI) is damage to normal lung tissue caused by thoracic tumor radiotherapy (RT), but effective interventions are lacking and its molecular mechanisms remain unclear....
Anatomy as a guide: Using learned priors for precise organ segmentation
March 2026
Accurate segmentation of abdominal organs from Computed Tomography (CT) is essential for clinical tasks such as radiotherapy planning but is hindered by ambiguity at organ boundaries. Standard deep...
Integration of conventional MRI and diffusion-weighted imaging for differential diagnosis of high-grade gliomas and metastatic brain tumors
March 2026
Brain tumors, particularly high-grade gliomas (HGG) and solitary brain metastases (SBM), often present with overlapping clinical and imaging features, complicating accurate diagnosis and management....
Feasibility of deep learning-based high-quality CBCT images for adaptive radiotherapy in rectal cancer
March 2026
Cone-beam computed tomography (CBCT) presents challenges for adaptive radiotherapy (ART) due to scatter artifacts and inaccurate CT numbers. While, deep learning-based synthetic CT (sCT) offers a potential...
Critical perspectives on nanoparticle-enabled radiopharmaceuticals: Integrating molecular imaging, targeted therapy, and theranostic translation
March 2026
Radiopharmaceuticals based on nanoparticles are transforming the landscape of molecular imaging, targeted therapy and theranostics. Nevertheless, despite the accelerating innovation, translation is...
The correlation between bone alteration and intestinal fibrosis of Crohn's disease: A preclinical μCT-based study on the bone-gut axis
March 2026
The relationship between osteoporosis and intestinal fibrosis, a prominent manifestation of Crohn's disease (CD), has not been fully investigated. Focusing on this correlation may offer new insights...
METTL3-activated CCNE2 promotes hepatocellular carcinoma cell growth, metastasis, stemness and radioresistance
March 2026
Methyltransferase-like 3 (METTL3) has been confirmed to participate in regulating hepatocellular carcinoma (HCC) progression. However, more roles and mechanisms of METTL3 in HCC progression still need...
Design semi-automated radio-synthesis strategy and synthesis of benzimidazole-based radiotracer 2-(4-(2-(fluoro-18F) ethyl) piperidin-1-yl) benzo imidazo[1,2-a] pyrimidine for Tau as a PET imaging agent
March 2026
Several studies have reported that benzimidazole-based structures are used in the diagnosis of Alzheimer's disease. Various modified benzimidazole-based structures serve as radiotracers. Among them,...
Proteomics combined with ultrasound radiomics predicts central lymph node metastasis in papillary thyroid carcinoma
March 2026
Accurate preoperative prediction of central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC) remains challenging. This study sought to develop and validate a combined model that combines...
Preclinical evaluation of [68Ga]Ga-DFO for molecular imaging of Vibrio cholerae infection
March 2026
In this study, a novel diagnostic radiopharmaceutical, [68Ga]Ga-DFO, was developed for positron emission tomography (PET) imaging of the pandemic infection of Vibrio cholerae....