Genotype switching in hepatitis B virus as a potential risk for vertical transmission from mother-to-child was first reported
2025
Hepatitis B virus (HBV) infection represents a significant global public health concern and is endemic in numerous populations. In China, mother-to-child transmission (MTCT) remains the predominant...
Recurrent cholera outbreaks in Nigeria: A review of the underlying factors and redress
2025
Cholera outbreaks remain a matter of public health since this outbreak of the epidemic is experienced almost every year. In June 2024, the African Region had registered 7964 new cases of cholera across...
Advances and challenges in the prevention, control and research of echinococcosis in China
2025
Echinococcosis is a group of chronic zoonotic parasitic diseases caused by the larval stage of Echinococcus tapeworms, which infect both humans and animals. Due to the complex life cycle, broad geographic...
A rare case of Trichosporon inkin bloodstream infection in an immunocompetent patient: Diagnostic challenges and antigenic cross-reactivity
2025
Trichosporon inkin is a rare opportunistic pathogen typically associated with superficial infections but can also cause invasive infections, particularly in immunocompromised hosts. Here, we report...
WHO report signals tuberculosis resurgence: Addressing systemic failures and revamping control strategies
2025
According to the World Health Organization's Global Tuberculosis Report 2024, tuberculosis (TB) has resurged as the leading cause of death from a single infectious agent, overtaking Coronavirus disease...
The Alongshan virus: A comprehensive review of its pathogenic characteristics, epidemiology, and detection strategies
2025
Alongshan virus (ALSV) is an emerging tick-borne segmented RNA virus belonging to the Flaviviridae family, first identified in Northeastern China in 2017. ALSV is currently classified within the Jingmenvirus...
The prevalence, impact, and control measures of brucellosis in Nigeria: An analytical study
2025
This study aimed to assess the prevalence, economic impact, and control measures of brucellosis in livestock and humans across four Nigerian states (Lagos, Kano, Oyo, and Kaduna) from 2018 to 2020....
Rabies in Africa: Vaccination coverage and strategies for elimination by 2030
2025
Rabies remains a significant public health threat in Africa, and disproportionately impacts vulnerable populations to cause thousands of deaths annually. Rabies is a preventable disease and control...
Circadian rhythm of mosquitoes: Blood feeding and disease transmission
2025
The circadian rhythm refers to the adjustment of behavioural rhythms of organisms' to the environmental cues. The rhythm adjusting and maintaining is done through an internal timekeeping mechanism....
mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed
2025
In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their...
The implications of Mpox for healthcare Providers: Understanding transmission, clinical presentation, and infection control
2025
Mpox, formerly known as monkeypox, is a zoonotic viral disease caused by the Monkeypox virus, a member of the Orthopoxvirus genus. Since the 2022 global outbreak, the virus has been increasingly reported...
A novel approach to disease modeling: The SEIVR model with a vulnerable compartment
2025
The SEIR model is a cornerstone in epidemiology and offers insights into the spread of infectious diseases. It extends the basic SIR model to include an Exposed (E) compartment, to account for the incubation...
Trends in the minimum inhibitory concentrations for four agents against methicillin-resistant Staphylococcus aureus in bloodstream infections in China: a 6-year multi-center study from 2017 to 2022
2025
Staphylococcus aureus bacteremia is a critical and pernicious infection, and in particular methicillin-resistant Staphylococcus aureus (MRSA) is increasing in treatment failure. This study analyzed...
Genomic insights into disease vectors: Divergent evolution of mosquitoes, tsetse flies, sand flies and kissing bugs
2025
Vector-borne diseases pose major global health challenges, with mosquitoes, tsetse flies, and sand flies serving as key insect vectors. This review explores the genomic basis of hematophagy, reproduction,...
Decoding the Bite: Sensory cues, host heterogeneity, and pathogen manipulation in mosquito host-seeking behavior
2025
Mosquitoes, primarily females, require blood meals for reproduction, making them prolific biters and major vectors of diseases such as malaria, dengue, Zika, and West Nile. This review synthesizes the...
Sexual development in apicomplexan parasites: past and future
2025
Sexual development is an important process in eukaryotic organisms that involves the fusion of gametes to produce genetically diverse offspring. In apicomplexan parasites, sexual development is crucial...
Genome-wide identification of characteristic nucleotide fragments for surveillance and subtype typing of influenza A viruses
2025
Influenza A viruses, members of the Orthomyxoviridae family, are major causative agents of past flu pandemics and can infect a wide range of hosts depending on their hemagglutinin (HA) and neuraminidase...
Recurring diphtheria outbreaks in Nigeria: A holistic review of challenges, knowledge and strategic recommendations for control
2025
Diphtheria is a vaccine-preventable bacterial disease that has contributed to the large number of deaths in Nigeria. There have been numerous outbreaks after the COVID-19 pandemic. However, the challenges...
Response to Chikungunya fever in China: are we ready?
2025
Chikungunya fever (CHIK) is caused by the Chikungunya virus (CHIKV), a mosquito-borne RNA virus of the Alphavirus genus (family Togaviridae). CHIK has been imported and caused several local epidemic...
Recent malaria outbreak in the USA: Risk of and response to malaria reintroduction in non-endemic regions
2024
The emergence of locally transmitted Plasmodium vivax malaria in Florida from May to July 2023 underscores the persistent threat of malaria reintroduction in non-endemic regions. The increasing instances...
S–6P exhibits better immunogenicity than S–2P at lower doses of COVID-19 mRNA vaccines
2024
The objective of this study was to determine whether a new combination of immunogens could be more effective than the S–2P design in terms of eliciting an immune response. The study aimed to use a unified...
In vitro culture and genetic modification of Babesia gibsoni
2024
Babesia gibsoni, a unicellular eukaryotic parasite causing babesiosis in dog, is primarily transmitted through tick feeding. The intraerythrocytic stage, during which the parasite reproduce within the...
Progress of exosomes in diagnosis of tuberculosis
2024
Tuberculosis (TB) is a globally prevalent infectious disease caused by Mycobacterium tuberculosis. A majority of TB patients develop a latent infection, making disease diagnosis more challenging. However,...
Global, regional, and national burden of dengue, 1990–2021: Findings from the global burden of disease study 2021
2024
Dengue is an acute viral infectious disease caused by the dengue virus and transmitted through mosquitoes. Although numerous studies have examined the global burden of dengue, comprehensive and systematic...
Machine learning models for predicting residual malaria infections using environmental factors: A case study of the Jazan region, Kingdom of Saudi Arabia
2024
Malaria is a global public health problem affecting more than 100 countries. Meteorological factors on the other hand represent a major driving force behind malaria transmission and other vector-borne...