TCMLCM: an intelligent question-answering model for traditional Chinese medicine lung cancer based on the KG2TRAG method
March 2025
To improve the accuracy and professionalism of question-answering (QA) model in traditional Chinese medicine (TCM) lung cancer by integrating large language models with structured knowledge graphs using...
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Artificial intelligence in personalized cardiology treatment
March 2025
Cardiovascular diseases are the leading cause of death, requiring innovative approaches for prevention, diagnosis, and treatment. Personalized medicine customizes interventions according to individual...
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Research progress in digital auscultation: equipment and systems, characteristic parameters, and their application in diagnosis of pulmonary diseases and syndromes
March 2025
Traditional Chinese medicine (TCM) auscultation has a long history, and with advancements in equipment and analytical methods, the quantitative analysis of auscultation parameters has determined. However,...
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External application of traditional Chinese medicine in combination with three-step analgesic ladder therapy for cancer-induced bone pain: a systematic review and meta-analysis
March 2025
To systematically evaluate the overall efficacy of external application of traditional Chinese medicine (EA-TCM) in combination with oral three-step analgesic ladder therapy for patients suffering from...
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Multi-target inhibition property of Persicaria hydropiper phytochemicals against gram-positive and gram-negative bacteria via molecular docking, dynamics simulation, and ADMET analysis
March 2025
To evaluate the antibacterial potential of bioactive compounds from Persicaria hydropiper (L.) (P. hydropiper) against bacterial virulence proteins through molecular docking (MD) and experimental v...
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Bioinformatics-based analysis of autophagy-related genes and prediction of potential Chinese medicines in diabetic kidney disease
March 2025
To predict the autophagy-related pathogenesis and key diagnostic genes of diabetic kidney disease (DKD) through bioinformatics analysis, and to identify related Chinese medicines....
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Analysis of clinical characteristics and diagnostic prediction of Qi deficiency and blood stasis syndrome in acute ischemic stroke
March 2025
To explore the clinical characteristics and methods for syndrome differentiation prediction, as well as to construct a predictive model for Qi deficiency and blood stasis syndrome in patients with acute...
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From digits towards digitization: the past, present, and future of traditional Chinese medicine
March 2025
Digitization is the inevitable path for the natural development of traditional Chinese medicine (TCM) in the context of the Fourth Industrial Revolution. The goal of TCM digitization is to generate...
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Traditional Chinese medicine phenomics research on glycolipid metabolism disorder: a review
March 2025
Traditional Chinese medicine (TCM) has demonstrated unique advantages in the prevention and treatment of chronic diseases such as glycolipid metabolism disorder. However, its widespread application...
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Modulation of colonic DNA methyltransferase by mild moxibustion and electroacupuncture in ulcerative colitis TET2 knockout mice
March 2025
To investigate the mechanism of in alleviating colonic mucosal inflammation in ten-eleven translocation (TET) protein 2 gene knockout (TET2-/-) mice with ulcerative colitis (UC) by regulating DNA methyltransferase...
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Integrating proteomics and targeted metabolomics to reveal the material basis of liver-gallbladder damp-heat syndrome in chronic hepatitis B
December 2024
To elucidate the biological basis of liver-gallbladder damp-heat syndrome (LGDHS) within the framework of traditional Chinese medicine (TCM) as a complementary diagnostic and therapeutic approach in...
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Classification of cold and hot medicinal properties of Chinese herbal medicines based on graph convolutional network
December 2024
To develop a model based on a graph convolutional network (GCN) to achieve efficient classification of the cold and hot medicinal properties of Chinese herbal medicines (CHMs)....
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Uric acid-lowering activity and mechanisms of Chinese medicines with medicine-food homology: a systematic study
December 2024
To summarize the uric acid-lowering effects and mechanisms of Chinese medicines with medicine-food homology, aiming to provide novel perspectives for the development of new anti-hyperuricemia (HUA)...
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TCMLLM-PR: evaluation of large language models for prescription recommendation in traditional Chinese medicine
December 2024
To develop and evaluate a fine-tuned large language model (LLM) for traditional Chinese medicine (TCM) prescription recommendation named TCMLLM-PR....
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Risk assessment of coronary artery occlusion based on integrated Chinese and western medicine data
December 2024
To develop an integrated risk model for coronary artery occlusion based on data of both traditional Chinese medicine (TCM) and western medicine data, and to evaluate the contribution of TCM-specific...
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Study on the facial spectrum and color characteristics of patients with essential hypertension
December 2024
To investigate the facial spectrum and color characteristics of patients with essential hypertension post administering antihypertensive drugs, establish a classification and evaluation model based...
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Research progress in Fangjiomics: methodologies, applications, and perspectives
December 2024
Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective. We reviewed recent advances in Fangjiomics,...
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Recent advancements in digital and traditional treatment strategies for major depressive disorder using medicinal herbs
December 2024
Integrating digital health technologies, including mobile applications and digital biomarkers, with traditional medicinal plants and phytochemicals may enhance the effectiveness of standard antidepressants....
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Harnessing traditional herbal medicine: molecular insights into diabetic wound healing for modern therapeutics
December 2024
This study aims to explore the molecular aspects of the wound-healing potential of medicinal plants through preclinical and clinical research. This review focuses on the theoretical support and therapeutic...
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The modulating of Qingguang’an II Formula on gut microbiota in mice with chronic high intraocular pressure by 16S rDNA sequencing
December 2024
To investigate the effects of Qingguang'an II Formula (QGA II) on the gut microbiota of mice with chronic high intraocular pressure (IOP) model, and explore its key microbiota for protecting the optic...
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Lightweight and polarized self-attention mechanism for abnormal morphology classification algorithm during traditional Chinese medicine inspection
September 2024
To propose a Light-Atten-Pose-based algorithm for classifying abnormal morphology in traditional Chinese medicine (TCM) inspection to solve the problem of relying on manual labor or expensive equipment...
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Metabolic characteristics of Qi-Yin deficiency and heat stagnation in liver meridian patterns of dry eye based on tear metabolomics
September 2024
To explore the metabolic differences between dry eye patients with Qi-Yin deficiency and heat stagnation in liver meridian patterns, and clarify their metabolic characteristics....
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A Rumsfeld Matrix test for acupuncture clinical trials
September 2024
This study examined the application of the Rumsfeld Matrix to acupuncture clinical trials, particularly those published in leading medical journals such as The Journal of the American Medical Association...
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