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ISSN: 2666-1381

Aquaculture derived hybrid skin patches for wound healing

•The proposed patches are based on the derivatives of fish and crabs.•The acellular fish skin present porous surface for drug loading.•The patch owns brilliant biocompatibility, antibacterial and angiogenesis...

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Polylysine complexes and their biomedical applications

•This review summarized the advanced development of the synthesis strategies of PLL•This review introduces the biomedical fields, where PLL are mainly utilized, such as cargo delivery, tissue adhesives,...

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Dual ultra-wideband (UWB) radar-based sleep posture recognition system: Towards ubiquitous sleep monitoring

•Dual radar performs better than single radar in classification.•Random forest with predetermined statistical features yielded 0.887 accuracy.•Deep learning classifiers doesn't not necessarily perform...

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Management of post-stroke depression (PSD) by electroencephalography for effective rehabilitation

•In this study, we provided a unique and systematic review on the most related literature of the clinical applications of EEG for PSD and offered a cross-section that is useful for determining optimal...

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Advanced surgical technologies for lung cancer treatment: Current status and perspectives

•The common lung cancer and their treatment methods are introduced.•Various emerging surgery methods used to lung cancer are summarized.•Application of imaging guided nanotechnology in lung cancer surgery...

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Chronic wounds: pathological characteristics and their stem cell-based therapies

•Give a detailed introduction of the pathological process involved in chronic wound healing and the mechanism of SCs in promoting chronic wound repair.•Highlight recent SC-based therapies for chronic...

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Spinal cord conduits for spinal cord injury regeneration

•The classification of spinal cord conduits for spinal cord injury repair were concluded.•The various sources and crosslinking methods for producing spinal cord conduits were reviewed.•The therapeutic...

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Advances in antioxidative nanozymes for treating ischemic stroke

•The characteristics of antioxidative nanozymes are dissertated.•The classes and properties of antioxidative nanozymes are discussed.•The recent advances of antioxidative nanozymes for treating ischemic...

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Strontium doped electrospinning fiber membrane with antibacterial and osteogenic properties prepared by pulse electrochemical method

•Composite fibers were prepared by electrostatic spinning and pulse electrochemical deposition.•PPy controls the slow release of Sr2+ and Cu2+ for a long time.•Good physiological stability and long-term...

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Adsorptive carbon-based materials for biomedical applications

•Adsorptive carbon-based materials have emerged as favorable candidates in biomedical adsorption or enrichment.•The classification and fabrication strategies of carbon-based materials are presented.•The...

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UV-induced senescence of human dermal fibroblasts restrained by low-stiffness matrix by inhibiting NF-κB activation

•PDMS substrates with tunable stiffness coated by fibronectin are rational designed and fabricated.•HDFs were more sensitive to UV induced ROS accumulation and cell senescence on stiff substrates.•Soft...

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Urinary analysis based on surface-enhanced Raman scattering for the noninvasive screening of lung cancer

•The Aunps-based SERS probes were developed for the detection of adenosine.•The platform can identify adenosine, uric acid, guanine and creatinine in urine.•The assay was successfully applied for the...

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Structural and biomechanical characterizations of acellular porcine mitral valve scaffolds: anterior leaflets, posterior leaflets, and chordae tendineae

•Quantitative DNA assay showed more than 90% reduction in DNA content, and griffonia simplicifolia (GS) lectin immunohistochemistry confirmed the complete lack of porcine α-Gal antigen in the acellular...

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Acoustofluidics for cell patterning and tissue engineering

•This review addresses the current developments and remaining challenges of advanced acoustofluidic techniques in bioengineering fields.•The fundamentals of acoustic manipulation and typical acoustofluidic...

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Wearable microneedle-integrated sensors for household health monitoring

•A novel wearable microneedle-based sensor for continuous and real-time ISF multi-biomarkers monitoring and analyzing.•This device integrated an array of disposable multiplex-sensing microneedles, reusable...

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Injectable hydrogels for spinal cord injury repair

•The development of injectable hydrogels for spinal cord injury treatment were reviewed.•The original sources of polymers and the crosslinking manners in forming injectable hydrogels were summarized.•The...

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Engineered olfactory system for in vitro artificial nose

•Artificial nose drew generous attention in the field of bionic organs.•Construction with sensing module, recognition system and functional structure are introduced.•Recognition technology, substrate...

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Mimicking the native bone regenerative microenvironment for in situ repair of large physiological and pathological bone defects

•Instead of simply using scaffolds or following the tradition principle of large bone defects treatment, we proposed a novel concept: bone regenerative microenvironment (BRM). Through the regulation...

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Engineered microneedles arrays for wound healing

•The advances of engineered microneedles arrays for wound healing were reviewed.•The design strategies, advanced applications and advantages of engineered microneedles arrays were summarized.•The challenges,...

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Engineered extracellular vesicles: Regulating the crosstalk between the skeleton and immune system

•Extracellular vesicles of natural origin mediate the crosstalk between immune system and skeleton.•Bioengineering techniques are used to tailor extracellular vesicles for enhanced targeting ability...

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A versatile approach for temporary storage and shipping of in vitro cultured cells, cell sheets and tissue engineered constructs – a preliminary report

•Device was made with readily available raw materials and can be used with ease in a DIY manner.•Device offers leak-proof and aseptic containment of the contents during storage and shipping process.•Device...

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Recent advances in chiral aggregation-induced emission fluorogens

•Chiral AIEgens can identify chiral molecules visually based on color change and precipitation reaction, quantitatively analyze chiral molecules, demonstrating its high selectivity, sensitivity and...

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Construction and application of liver cancer models in vitro

•The current methods or techniques for preparing 3D in vitro liver cancer models were introduced.•The relevant applications of 3D in vitro liver cancer models were summarized.•The advantages and disadvantages...

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