Future perspective on chronic kidney disease management
September 2025
Over-activation of the sympathetic nervous system is one of the major characteristics in chronic kidney disease (CKD), with renal ischemia playing a pivotal role in its development. While various pharmacologic...
Pain trajectory after total knee arthroplasty (TKA) with prolonged use of outpatient adductor canal catheters
September 2025
In this prospective observational study, we sought to evaluate whether the prolonged use of adductor canal nerve block catheters provides benefits for patients undergoing primary total knee arthrop...
Mechanism of antidepressant action of ketamine and differences between its two enantiomers
September 2025
Ketamine has been widely used since its discovery, and in addition to its anesthetic effects, in recent years it has been found to exhibit rapid and sustained antidepressant effects in rodent models...
From static to dynamic: Artificial intelligence revolution in perioperative care through multimodal data fusion and closed-loop optimization
September 2025
The integration of artificial intelligence (AI) into perioperative care represents a paradigmatic transformation from static decision frameworks to dynamic, adaptive systems. This comprehensive review...
Remimazolam in anesthesia and sedation: A narrative review
September 2025
Remimazolam, an innovative sedative, provides a rapid onset and quick recovery by being rapidly hydrolyzed into pharmacologically inactive CNS7054 via ubiquitous nonspecific esterases. Its pharmacokinetic...
Open lung ventilation with low tidal volumes, staircase recruitment maneuvers, high PEEP and decremental PEEP titration vs ARDSNet in ARDS: A systematic review and meta-analysis
September 2025
The impact of open lung ventilation (OLV) with low tidal volumes (TV), staircase recruitment maneuvers (SRMs), high positive end-expiratory pressure (PEEP), and decremental PEEP titration on acute respiratory...
Clinical practice guidelines for postoperative pain management in adults (2024 edition)
September 2025
Acute pain differs in many aspects from chronic pain states and can arise from various etiologies. Recent years have seen advancements in postoperative acute pain management, which is a critical component...
Practice advisory on the management of the perioperative period of scoliosis correction surgery
September 2025
Scoliosis correction surgery is a complex procedure aimed at rectifying the spinal lateral curvature and rotation. Perioperative anesthetic management is a critical determinant of both surgical success...
Neural mechanisms of pain susceptibility and resilience: Insights from a socially transferred allodynia mouse model
September 2025
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September 2025
What is new in cardiac anesthesia in 2024?
June 2025
Recent advances in cardiac anesthesia have led to improved patient care and safety. In 2024, there is a growing focus on patient-centered approaches aimed at improving overall outcomes. This includes...
Safety and feasibility of a rapid reversible induction strategy in anesthesia induction
June 2025
Unexpected airway management challenges during anesthesia induction—particularly "Cannot Intubate, Cannot Ventilate" (CICV) scenarios—pose significant risks of hypoxemia and hemodynamic instability....
Myocardial infarction with non-obstructive coronary arteries in a patient undergoing nephrectomy under general anesthesia
June 2025
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is an uncommon but clinically significant condition, particularly during the perioperative period. Its diagnosis is challenging...
Perioperative multivariate analysis and risk prediction of acute kidney injury after cardiac surgery: Based on dynamic temperature changes during cardiopulmonary bypass
June 2025
Temperature variations during cardiopulmonary bypass (CPB) may significantly contribute to the development and progression of acute kidney injury (AKI) after cardiac surgery. We tested the hypothesis...
Efficacy and safety of continuous infusion of remimazolam for sedation in elderly patients undergoing colonoscopic polypectomy: A non-inferiority prospective controlled clinical trial
June 2025
To study the efficacy and safety of a bolus dose of remimazolam followed by its continuous infusion, and to identify its optimal maintenance dose in elderly patients undergoing colonoscopic polypectomy,...
Prognostic value of echocardiogram and cardiac biomarkers through three waves of COVID-19
June 2025
COVID-19 has had a significant impact on the scientific field. The multitude of effects this virus has on different organ systems is a continuously expanding range of study. The purpose of this study...
Chronic stress contributes to long-term isoflurane anesthesia-induced cognitive dysfunction via histone acetylation modulated by RbAp48-HDAC2 in male mice
June 2025
Histone deacetylation has been shown to be related to memory decline in aging and neurodegenerative diseases. Chronic stress, which has been shown to induce histone deacetylation, is associated with...
Spinal TREM2/PI3K/Akt signal axis elicits microglial activation and aggravates bone cancer pain
June 2025
The TREM2 signaling pathway is activated in multiple pain conditions; nevertheless, its role in the regulation of bone cancer pain remains largely unexplored. The persistent pathological progression...
Intraoperative electroencephalography predicts postoperative nausea and vomiting in laparoscopic sleeve gastrectomy
June 2025
Postoperative nausea and vomiting (PONV) is one of the most common causes for rehospitalization and emergency department visits after bariatric surgery. The current understanding of risk factors prediction...
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June 2025
Anesthetic management of delayed malignant hyperthermia during scheduled right frontotemporal craniotomy
March 2025
Malignant hyperthermia is a critical complication that arises when certain anesthetics are administered to susceptible patients, posing a significant risk of mortality if not promptly identified and...
Impact of transcutaneous electrical acupoint stimulation combined with aromatherapy on postoperative nausea and vomiting in patients undergoing microvascular decompression surgery: A prospective randomized study
March 2025
Microvascular decompression (MVD) surgery is frequently associated with severe postoperative nausea and vomiting (PONV). This prospective randomized trial aimed to evaluate the combined efficacy of...
A narrative review on multimodal spinal anesthesia: Old technique and new use
March 2025
Spinal anesthesia has a long history in providing safe and effective anesthesia and analgesia. Its continuous evolution in block placement techniques with or without ultrasound assistance, options of...
Interventional neuromodulation techniques for cervicogenic headache
March 2025
Cervicogenic headache is a debilitating secondary headache condition that reduces the quality of life for many. Its etiology involves pathologies in one or more of the complex cervical structures, such...
Anesthesia for fetal interventions: Caring for mother and fetus prior to birth
March 2025
Fetal surgery is an expanding domain in which the developing fetus receives therapeutic interventions aimed at reducing mortality and/or morbidity. It presents unique challenges to the anesthesiologist,...