Efficacy and safety of continuous infusion of remimazolam for sedation in elderly patients undergoing colonoscopic polypectomy: A non-inferiority prospective controlled clinical trial
June 2025
To study the efficacy and safety of a bolus dose of remimazolam followed by its continuous infusion, and to identify its optimal maintenance dose in elderly patients undergoing colonoscopic polypectomy,...
Prognostic value of echocardiogram and cardiac biomarkers through three waves of COVID-19
June 2025
COVID-19 has had a significant impact on the scientific field. The multitude of effects this virus has on different organ systems is a continuously expanding range of study. The purpose of this study...
Chronic stress contributes to long-term isoflurane anesthesia-induced cognitive dysfunction via histone acetylation modulated by RbAp48-HDAC2 in male mice
June 2025
Histone deacetylation has been shown to be related to memory decline in aging and neurodegenerative diseases. Chronic stress, which has been shown to induce histone deacetylation, is associated with...
Spinal TREM2/PI3K/Akt signal axis elicits microglial activation and aggravates bone cancer pain
June 2025
The TREM2 signaling pathway is activated in multiple pain conditions; nevertheless, its role in the regulation of bone cancer pain remains largely unexplored. The persistent pathological progression...
Intraoperative electroencephalography predicts postoperative nausea and vomiting in laparoscopic sleeve gastrectomy
June 2025
Postoperative nausea and vomiting (PONV) is one of the most common causes for rehospitalization and emergency department visits after bariatric surgery. The current understanding of risk factors prediction...
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June 2025
Anesthetic management of delayed malignant hyperthermia during scheduled right frontotemporal craniotomy
March 2025
Malignant hyperthermia is a critical complication that arises when certain anesthetics are administered to susceptible patients, posing a significant risk of mortality if not promptly identified and...
Impact of transcutaneous electrical acupoint stimulation combined with aromatherapy on postoperative nausea and vomiting in patients undergoing microvascular decompression surgery: A prospective randomized study
March 2025
Microvascular decompression (MVD) surgery is frequently associated with severe postoperative nausea and vomiting (PONV). This prospective randomized trial aimed to evaluate the combined efficacy of...
A narrative review on multimodal spinal anesthesia: Old technique and new use
March 2025
Spinal anesthesia has a long history in providing safe and effective anesthesia and analgesia. Its continuous evolution in block placement techniques with or without ultrasound assistance, options of...
Interventional neuromodulation techniques for cervicogenic headache
March 2025
Cervicogenic headache is a debilitating secondary headache condition that reduces the quality of life for many. Its etiology involves pathologies in one or more of the complex cervical structures, such...
Anesthesia for fetal interventions: Caring for mother and fetus prior to birth
March 2025
Fetal surgery is an expanding domain in which the developing fetus receives therapeutic interventions aimed at reducing mortality and/or morbidity. It presents unique challenges to the anesthesiologist,...
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March 2025
Anesthetic procedure for transapical beating-heart septal myectomy in patients with hypertrophic obstructive cardiomyopathy: Report of three cases
December 2024
Septal myectomy is the gold standard for treating severe hypertrophic obstructive cardiomyopathy (HOCM). Recently, the cardiothoracic surgery team from our hospital has developed a novel surgical approach...
The impact of esketamine combined with butorphanol on postoperative analgesia and maternal psychological status after cesarean section: A randomized controlled study
December 2024
Cesarean delivery is a highly invasive procedure that causes moderate to severe pain. Persistent postoperative pain affects the parturients’ rapid postoperative recovery. Therefore, we aim to investigate...
Roles of orexinergic and noradrenergic neuronal activity in ketamine-induced analgesia: A study using an orexin/ataxin-3 transgenic rat model
December 2024
Orexin, a neuropeptide, physiologically interacts with locus coeruleus noradrenergic (LC-NA) activity. We hypothesized that this interaction affects ketamine-induced acute analgesia....
Evaluation of needle to nerve interaction for neurological complications in ultrasound-guided interscalene brachial plexus blocks
December 2024
The use of regional anesthesia techniques carries a well-known risk of perioperative neurological complications. The interscalene approach to brachial plexus block (ISB) is associated with the largest...
The role of ketamine and its enantiomer in managing depression and pain in cancer patients: A narrative review
December 2024
Depression and pain are common comorbidities in cancer patients, and ketamine, a dissociative anesthetic, has shown potential in managing both. This review summarizes current literature on ketamine...
Neoadjuvant chemotherapy and perioperative cardiotoxicity
December 2024
Malignant tumors constitute a major threaten to human health and are among the most serious public health challenges both in China and globally. Many patients with malignancy require neoadjuvant chemotherapy...
The environmental effects of anesthetic agents and anesthesia practices
December 2024
Anesthesia is a critical domain with considerable capacity to reduce the carbon footprint of healthcare on the environment, particularly in terms of climate change. Volatile anesthetics are halogenated...
Relationship between diet and postoperative pain: A scoping review
December 2024
Poorly controlled postoperative pain is a risk factor for persistent post-surgical pain. Inflammation, as influenced by diet, has been incriminated as a significant factor in pain sensitivity and persistent...
The regulatory role of dexmedetomidine in NLRP3 inflammasome-related organ protection
December 2024
Organ protection is paramount during the perioperative period. Dexmedetomidine, a commonly used anesthetic, has gained attention for its potential anti-inflammatory and organ-protective properties....
Efficacy and safety of anrikefon injection for postoperative analgesia in specific patient groups (elderly, liver damage, renal damage) after abdominal surgery
December 2024
This study aims to evaluate the efficacy and safety of anrikefon for postoperative analgesia following abdominal surgery in specific populations, including elderly patients and those with mild to moderate...
Frontiers and emerging trends of psychotherapy applications in anesthesiology: A comprehensive bibliometric analysis
December 2024
Psychological therapy can mitigate preoperative negative emotions in patients and facilitate postoperative recovery, all while avoiding the side effects associated with sedative medications. However,...
Mapping the publication trends of synaptic plasticity in neuropathic pain: A bibliometric analysis
December 2024
Neuropathic pain typically arises following injury or damage to the somatic nervous system, a chronic and debilitating condition with complex mechanisms. Synaptic plasticity, the changes in neuronal...
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December 2024