Promoting brain health in older surgical patients: A pre-post evaluation of an educational module
September 2026
Older surgical patients are at a high risk for perioperative neurocognitive disorders, such as postoperative delirium (POD), yet awareness and engagement in brain health are low. The preoperative period...
Phenotype-based modeling of postoperative ventilatory liberation failure: A dynamic mechanistic framework for precision perioperative medicine
September 2026
Postoperative ventilatory liberation failure is usually recorded as a late binary event, although vulnerability often develops earlier through anesthesia, mechanical ventilation, neuromuscular blockade,...
Prediction of postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass grafting: A machine learning model
September 2026
The incidence of cardiac surgery-associated acute kidney injury (CSA-AKI) is 26.0%–28.5%. Among cardiac procedures, off-pump coronary artery bypass grafting (OPCABG) is a major contributor to CSA-AKI....
Predictive value of preoperative T cell phenotypes for postoperative pulmonary complications in elderly patients undergoing thoracic surgery
September 2026
Postoperative pulmonary complications (PPCs) significantly impair patient recovery, yet reliable predictors remain scarce. T cell and mitochondrial phenotypic marker abnormalities are recognized as...
Association of preoperative state anxiety and early postoperative recovery in living kidney donors undergoing nephrectomy: A prospective observational study
September 2026
Preoperative anxiety may influence perioperative physiological responses, early postoperative recovery, postoperative pain, and patient satisfaction in living kidney donors. This study evaluated the...
Intraoperative neurophysiological monitoring (IONM) in neurosurgery: A critical appraisal of established practices, ongoing controversies, and future trajectories
June 2026
Intraoperative neurophysiological monitoring (IONM) has evolved from a novel technique into an evidence-based standard treatment method for high-risk neurosurgical and spinal surgeries. Its effectiveness...
Prevalence of cognitive impairment in older medical inpatients: A systematic review and meta-analysis
June 2026
Cognitive impairment is common among older adults and is associated with adverse outcomes such as prolonged hospital stays and increased mortality. Many of the medical inpatients subsequently undergo...
The application value of frailty assessment tools in the perioperative period: A narrative review
June 2026
Frailty is a clinical syndrome characterized by reduced physiological reserves and multisystem dysfunction, which markedly elevates the risk of postoperative complications and delayed functional recovery,...
A web-based two-stage prediction model for postoperative pulmonary complications using preoperative and intraoperative data
June 2026
Most existing models for predicting postoperative pulmonary complications (PPCs) rely solely on preoperative variables and lack integration of intraoperative data or clinical tools for application....
Obstructive fibrinous tracheal pseudomembrane complicated with bronchial mucus plug: A rare post-intubation complication case report
June 2026
Obstructive fibrinous tracheal pseudomembrane (OFTP) is a rare complication associated with endotracheal intubation. Elderly patients constitute a high-risk population for bronchial mucus plugging and...
Comparison of functional disability in older surgical patients with and without probable cognitive impairment: A longitudinal prospective cohort study
June 2026
Understanding the recovery trajectory of functional disability in older adults with cognitive impairment can enhance perioperative care through early identification of at-risk patients, risk stratification,...
Intraoperative blood pressure strategies and neurocognitive outcomes: A systematic review
June 2026
Intraoperative blood pressure instability during anesthesia may compromise cerebral perfusion and has been associated with postoperative delirium and perioperative neurocognitive disorders. However,...
TOC
June 2026
Cocktail-style multifunctional resuscitation fluids: Where are we now in 2026?
March 2026
For over half a century, fluid resuscitation has traditionally included crystalloids for volume expansion and colloids for potential oncotic advantage. The paradigm, however, could be shifting now....
Acute cerebral infarction caused by severe anaphylactic shock: A case report
March 2026
Perioperative anaphylactic reactions, especially those induced by colloid solutions like gelatins, can lead to severe hypotension and tissue hypoperfusion, with potential serious complications....
Electroencephalographic phenotypes of postoperative delirium in the perioperative period
March 2026
Postoperative delirium (POD) is a common and severe complication among older surgical patients. Perioperative electroencephalography (EEG) monitoring provides a noninvasive, real-time window into cerebral...
Advances in biomarkers for myocardial injury after non-cardiac surgery
March 2026
Myocardial injury after non-cardiac surgery (MINS) is a common and clinically important postoperative complication associated with increased short- and long-term mortality. As most cases lack typical...
Propofol treatment correlates with changes in pain sensitivity and thalamocortical glutamate/GABA balance in sleep-deprived mice
March 2026
Sleep disorders profoundly impair patients’ daily quality of life and present substantial challenges to clinical management. Accumulating evidence has shown that propofol improves sleep architecture...
Mechanisms of the RGS12-GPX4-ACSL4 signaling axis in regulating ferroptosis during myocardial ischemia-reperfusion injury
March 2026
Acute myocardial infarction (AMI) is one of the leading causes of death worldwide. Timely reperfusion therapy following AMI can effectively salvage ischemic cardiomyocytes. However, myocardial ischemia-reperfusion...
Remote assessment of instrumental activities of daily living and cognitive impairment in older surgical patients
March 2026
We aimed to investigate the prevalence of instrumental activities of daily living (IADL) dependence in older surgical patients, its association with cognitive impairment, and risk factors associated...
TOC
March 2026
Anxiety and depression in non-cardiac surgical patients and associations with adverse outcomes: A systematic review and meta-analysis
December 2025
Mental health disorders such as anxiety and depression are associated with advanced disease at presentation, reduced treatment uptake, and worse postoperative outcomes. Despite this, preoperative screening...
Perioperative predictors of complications in open abdominal aortic surgery: A retrospective analysis under a structured perioperative goal-directed therapy protocol
December 2025
Perioperative goal-directed therapy (PGDT) optimizes hemodynamics in high-risk vascular surgery. However, data on postoperative risk factors and temporal hemodynamic and arterial blood gas (ABG) data...
Contraceptive implant removal: Case report and the role of an ultrasound-trained anesthesiologist in perioperative localization and regional anesthesia
December 2025
Contraceptive implants offer a long-term reversible option for contraception. While palpable implants can be removed under local anesthesia in an office setting, nonpalpable implants can present greater...
Association between preoperative anemia and postoperative delirium in elderly patients undergoing total hip arthroplasty with combined spinal-epidural anesthesia: A retrospective cohort study
December 2025
The effect of preoperative anemia on postoperative delirium (POD) risk in elderly patients undergoing total hip arthroplasty (THA) with spinal-epidural anesthesia remains unclear. This study aimed to...