Special Issue on [Diagnosis, prevention and treatment of major chronic diseases and drug application research and development]

Introduction:

In recent years, the incidence of chronic diseases such as glucolipid metabolic disorders, coronary heart disease, hypertension and asthma has been steadily increasing. Meanwhile, conditions such as hepatitis B, AIDS, chronic kidney disease, chronic obstructive pulmonary disease, cognitive impairments, mental illnesses, rheumatoid arthritis, gastrointestinal inflammatory diseases, tumors, hematologic diseases, and immune-related diseases have also drawn widespread attention. These major chronic diseases have major impacts on the physiological, psychological and economic burdens of the population.

China places great emphasis on diagnosis, prevention, treatment and drug development to tackle medical conditions. Ongoing efforts are in place to increase scientific research investment and policy support. In recent years, China has formulated the “Healthy China 2030” blueprint, the Medium- and Long-Term Plan for the Prevention and Treatment of Chronic Diseases (2017-2025), and the Healthy China Action Plan (2019-2030), aiming to fully promote the diagnosis, prevention, treatment, and drug development to address major chronic diseases.

To date, the mechanisms underlying the occurrence and development of many major chronic diseases remain unelucidated. Developing relevant disease models can help to uncover the mechanisms of these diseases and to identify treatment targets. New methods, techniques, and biomarkers for the diagnosis and prevention of major chronic diseases are emerging and gradually being validated and applied clinically. The pharmacology, efficacy, pharmacokinetics and other aspects of drugs for the treatment of major chronic diseases are also being thoroughly researched, providing effective weapons for conquering these diseases.

Notably, the inheritance, innovation and development of traditional Chinese medicine are important components to promote the cause of Healthy China. It is therefore worth further exploring traditional Chinese medicine and tap its potential to prevent and treat major chronic diseases.

At the same time, novel treatment methods such as stem-cell therapy and organoid-based therapy have broad prospects for application and development in the treatment of major chronic diseases. New technologies and methods such as gene editing technology, nanoparticle drug delivery system, and artificial intelligence technology greatly enrich the diagnosis, prevention, treatment, and drug development of major chronic diseases. Modern high-precision instruments also play an indispensable role in the diagnosis and treatment of major chronic diseases.

The organization of this special issued stemmed from our aim to gather the achievements in the diagnosis, treatment and drug development to address major chronic diseases in China, strengthen the comprehensive concept of using new drugs and technologies to prevent and treat major chronic diseases, and promote research on the diagnosis, treatment and drug development. We sincerely invite you to submit research papers and reviews related to these topics. As a token of gratitude for the support of the authors, a remuneration of 1,000 to 5,000 yuan per article (RMB) will be provided after the formal publication of the accepted manuscripts.

Topics include but are not limited to:

• Research on the occurrence and development mechanisms of major chronic diseases
• New methods and methods for diagnosis, prevention and treatment of major chronic diseases, discovery of markers, etc.
• Model research on major chronic diseases
• Clinical drug research on major chronic diseases
• Research on the pharmacology and pharmacodynamics of drugs used to treat major chronic diseases
• Research on the pharmacokinetics of major chronic disease treatment drugs
• The application of traditional medicine in the prevention and treatment of major chronic diseases and resource mining
• Research on the prevention and treatment of major chronic diseases with traditional Chinese medicine ·Research on the application and development of targeted drugs and biological drugs in the treatment of major chronic diseases
• Research on the application and development of new treatments such as stem cell therapy and organoid therapy in the treatment of major chronic diseases
• The application of new technologies and methods such as gene editing technology, targeted drug delivery technology, and artificial intelligence technology in major chronic diseases
• The application and development of modern high-precision instruments in the diagnosis and treatment of major chronic diseases

Important Deadlines:

• Submission deadline: 15 June 2024

Submission Instructions:

Please read the Guide for Authors before submitting. All articles should be submitted online, please select [Diagnosis, prevention and treatment of major chronic diseases and drug application research and development] on submission.

Guest Editors:

Huang Guangrui   Beijing University of Chinese Medicine

Ye Linhu   The Sixth Affiliated Hospital of South China University of Technology (Foshan Nanhai District People's Hospital)

Zhang Hongliang   The First Affiliated Hospital of Guangxi Medical University

Liu Song   Guangdong Pharmaceutical University