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ISSN: 2667-2405

Liquid-liquid phase separation: Fundamental physical principles, biological implications, and applications in supramolecular materials engineering

Liquid-liquid phase separation (LLPS) is a captivating phenomenon in which a uniform mixture spontaneously divides into two liquid phases with differing component concentrations. It is prevalent in...

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Supramolecular fluorescence biosensing based on macrocycles

Fluorescence sensing converts chemical events into measurable readings by utilizing fluorescence signals for the qualitative or quantitative detection of specific analytes. Supramolecular chemistry,...

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Self-healing hydrogels based on reversible noncovalent and dynamic covalent interactions: A short review

The self-healing capability of a material refers to its ability to autonomously heal fractures or defects and restore its original structures and functionalities. Self-healing hydrogels, with enhanced...

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Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application

Adhesive bonding to diverse substances is vital to a great number of the established, cutting-edge and emerging applications. We have witnessed, in the last few years, the transformative progress in...

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Supramolecular co-assembled hybrid hydrogels for antibacterial therapy

Bacterial infections arising from antibiotic-resistant strains represent a formidable global health threat. In the realm of antibacterial therapies, supramolecular hydrogels stand out with unique advantages...

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Engineering coacervate droplets towards the building of multiplex biomimetic protocells

The origin of life on Earth remains one of the biggest open questions in science. Despite recent advances in molecular mechanism of cell biology, a large blind spot still exists between non-living matter...

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Fabrication of the polyetherketoneketone-reinforced nano-hydroxyapatite composites as inspired by the cortical bone

•The cortical bone-inspired composites were produced successfully by 20 vol% poly-dopamine (pDA)-nano hydroxyapatite (nHA) and 2 wt% PVA/PEKK.•pDA modified nano hydroxyapatite (nHA) slurries can fabricate...

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Stimuli-responsive hydrogel sponge for ultrafast responsive actuator

lA thermo-responsive PNIPAm hydrogel sponge with locally aggregated PNIPAm polymer network was constructed with the assistance of ice crystals.lThe PNIPAm hydrogel sponge can realize ultrafast de-swelling/swelling...

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Mechanically Interlocked Biomacromolecules

Mechanical interlocking is a prominent phenomenon both in macroscopic objects and in microscopic molecules. Not only is it aesthetically appealing, it also leads to unique properties such as extraordinary...

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Perylene diimide supramolecular aggregates: Constructions and sensing applications

Perylene diimides (PDIs) with high fluorescence quantum yield and well π-conjugated plane have been widely studied to construct supramolecular aggregates via noncovalent interactions and to further...

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Interfacial self-assembly of nanoparticles into macroscopic, monolayered films

This article offers an overview of recent advances in directing self-assembly of nanoparticles (NPs) at the interfaces between two immiscible fluids, which is aimed at emphasizing that the fluidic interfaces...

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Self-powered assemblies for tissue engineering applications

•It systematically summarizes the basic physical rules underlining electric field generations and provide a practical guide for the designing of electrically active supramolecular assemblies.•The general...

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Well-Tunable, 3D-printable, and Fast Autonomous Self-Healing Elastomers

Self-healing elastomers provide extended longevity of functional materials, due to their unique adaptability and durability. However, a major scientific challenge remains in developing materials with...

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Exploring water−macromolecule interactions at the single-molecule level: A comprehensive review

Water is ubiquitous and indispensable on the Earth. Its importance has long been recognized on a macroscopic scale. However, it took a long time to comprehend the impact of water molecules on the microscopic...

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Supramolecular microgels/microgel scaffolds for tissue repair and regeneration

Biomedical microgels are a novel type of materials with promising perspectives for repair and regeneration of multi-types of tissues and organs due to their highly hydrated nature, tunable microporous...

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A visualizable strategy to real-time monitor chiral block copolypeptide assembly by AIE fluorescent probes

Aggregation-induced emission (AIE) luminogens show great potential in many applications. In this study, we have synthesized diblock copolymers poly (ethylene glycol) -b-poly (9-anthrylmethyl-L-lysine)...

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Visualizing polymer diffusion in hydrogel self-healing

Self-healing hydrogels are attractive to extend material lifetime by rapid recovery from damage; the underlying healing mechanism regarding polymer diffusion are of broad research interest. However,...

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Towards sturdy and sensable pressure-sensitive adhesive through hierarchical supramolecular interaction

•High bonding strength (1340kPa) of PSA is achieved via hierarchical supramolecular interaction.•Ionic PSA exhibit excellent stress-sensing capability endowing it with a fast response to external stress...

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Progress for the development of antibacterial surface based on surface modification technology

With the increasing requirement for antibacterial surface especially in biomedical apparatus, constructing the new material surface with bactericidal activity for combating the infection caused by multi-resistant...

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Exploring the role of British dementia protein-2 (Bri2) and its BRICHOS domain in neurodegenerative disorders

Protein functionality hinges on precise three-dimensional structures, while molecular chaperones orchestrate folding, proteome maintenance, and proteostasis. Recent attention has focused on BRICHOS...

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The role of filamentous membraneless organelle in 3UTR-mediated Protein-Protein interfaces and localization: TIGER Domain

Cells contain numerous membrane-less (MLOs) and multiple membrane-bound organelles. Most of the MLOs have a spherical shape except for a few organelles (that have a filamentous appearance, e.g. FXR1...

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Exploring chemical space and structural diversity of supramolecular peptide materials

Searching chemical space and expanding the structural diversity of supramolecular self-assembly based on the development of combinatorial libraries is significant to the guided design of bio-inspired...

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A self-cascade terpolymer platform for amplified chemo-chemodynamic therapy with synergistic immunogenic cell death enhancement

Chemodynamic therapy, which relies on the generation of cytotoxic radicals, can be amplified by a nanoplatform that produces hydroxyl radicals while also compromising natural radical scavenging mechanisms....

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Reconfigurable structured liquids

The past decades have witnessed the discovery and rapid development of adaptable, reconfigurable all-liquid systems where, by the interfacial assembly and jamming of nanoparticles (NPs), a liquid-liquid...

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Bio-inspired nano-/micro-channels via supramolecular assembling: From fundamentals to applications

Ion channels play a vital role in regulating the flow of ions across cell membranes to maintain physiological functions. Mimicking this biological process and fabricating artificial nano-/micro-channels...

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