Exploring the role of British dementia protein-2 (Bri2) and its BRICHOS domain in neurodegenerative disorders
December 2024
Protein functionality hinges on precise three-dimensional structures, while molecular chaperones orchestrate folding, proteome maintenance, and proteostasis. Recent attention has focused on BRICHOS...
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The role of filamentous membraneless organelle in 3UTR-mediated Protein-Protein interfaces and localization: TIGER Domain
December 2024
Cells contain numerous membrane-less (MLOs) and multiple membrane-bound organelles. Most of the MLOs have a spherical shape except for a few organelles (that have a filamentous appearance, e.g. FXR1...
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Mechanically Interlocked Biomacromolecules
December 2024
Mechanical interlocking is a prominent phenomenon both in macroscopic objects and in microscopic molecules. Not only is it aesthetically appealing, it also leads to unique properties such as extraordinary...
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Exploring water−macromolecule interactions at the single-molecule level: A comprehensive review
December 2024
Water is ubiquitous and indispensable on the Earth. Its importance has long been recognized on a macroscopic scale. However, it took a long time to comprehend the impact of water molecules on the microscopic...
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Fabrication of the polyetherketoneketone-reinforced nano-hydroxyapatite composites as inspired by the cortical bone
December 2024
•The cortical bone-inspired composites were produced successfully by 20 vol% poly-dopamine (pDA)-nano hydroxyapatite (nHA) and 2 wt% PVA/PEKK.•pDA modified nano hydroxyapatite (nHA) slurries can fabricate...
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Supramolecular co-assembled hybrid hydrogels for antibacterial therapy
December 2024
Bacterial infections arising from antibiotic-resistant strains represent a formidable global health threat. In the realm of antibacterial therapies, supramolecular hydrogels stand out with unique advantages...
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Supramolecular fluorescence biosensing based on macrocycles
December 2024
Fluorescence sensing converts chemical events into measurable readings by utilizing fluorescence signals for the qualitative or quantitative detection of specific analytes. Supramolecular chemistry,...
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A visualizable strategy to real-time monitor chiral block copolypeptide assembly by AIE fluorescent probes
December 2024
Aggregation-induced emission (AIE) luminogens show great potential in many applications. In this study, we have synthesized diblock copolymers poly (ethylene glycol) -b-poly (9-anthrylmethyl-L-lysine)...
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A self-cascade terpolymer platform for amplified chemo-chemodynamic therapy with synergistic immunogenic cell death enhancement
December 2024
Chemodynamic therapy, which relies on the generation of cytotoxic radicals, can be amplified by a nanoplatform that produces hydroxyl radicals while also compromising natural radical scavenging mechanisms....
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Temperature-Responsive Self-Assembly Nanochaperone Protects Green Fluorescent Proteins from Thermal Denaturation
December 2024
Protein products perform important roles in the biochemistry field, but the thermal inactivation of proteins will increase the difficulty of their transport, storage and application. Therefore, improving...
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Hydrogen-bonding induced assembly of polymer-grafted nanoparticles towards photothermal antibacterial activities
December 2024
•Hydrogen-bonding interactions induce the self-assembly of polymer-grafted nanoparticles (PGNPs) in a good solvent.•The PGNP assemblies with controllable size can be obtained by regulating the concentration...
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Stretchable and self-healable lithium-ion batteries with all-in-one configuration
Available online 22 April 2024
•The LIB exhibits both stretchability and self-healability.•The electrolyte and electrodes form fused interfaces by the exchange of imine bond.•The LIB can supply power upon stretch or after being cut...
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Dynamic Covalent Bond-Based Materials: From Construction to Biomedical Applications
Available online 18 April 2024
Dynamic covalent bonds (DCBs) have received significant interest due to their unique reversibility and stimuli-responsiveness. The introduction of DCBs provides materials with self-healing and controllable...
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Exploring chemical space and structural diversity of supramolecular peptide materials
December 2023
Searching chemical space and expanding the structural diversity of supramolecular self-assembly based on the development of combinatorial libraries is significant to the guided design of bio-inspired...
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Perylene diimide supramolecular aggregates: Constructions and sensing applications
December 2023
Perylene diimides (PDIs) with high fluorescence quantum yield and well π-conjugated plane have been widely studied to construct supramolecular aggregates via noncovalent interactions and to further...
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Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application
December 2023
Adhesive bonding to diverse substances is vital to a great number of the established, cutting-edge and emerging applications. We have witnessed, in the last few years, the transformative progress in...
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In situ supramolecular self-assembly for alleviating multidrug resistance in cancer
December 2023
Drug resistance is one of the major causes of cancer treatment failures. In recent years, to combat the issue of drug resistance, a large volume of strategies has been established along the development...
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Block copolymer particles with tunable and robust internal nanostructures by combining hydrogen-bonding and crosslinking
December 2023
Nanostructured block copolymer (BCP) particles are attractive due to their ordered internal structures, unique shape and surface patterns; however, their structural integrity can be easily lost because...
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Hydrazide–pillar[5]arene-mediated silver nanoparticles for highly efficient reductive degradation of organic dyes
December 2023
•Supramolecular method for organic dyes degradation.•Synthetic macrocycles assist in the preparation of AgNPs.•Hybrid material for efficient catalysis....
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Self-powered assemblies for tissue engineering applications
December 2023
•It systematically summarizes the basic physical rules underlining electric field generations and provide a practical guide for the designing of electrically active supramolecular assemblies.•The general...
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An injectable macroporous hydrogel templated by gasification reaction for enhanced tissue regeneration
December 2023
Owing to excellent biocompatibility, tunable modulus to match biological tissues, full of water environment, and wide range of constituents, injectable hydrogels have always been preferred as superior...
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Exploring computational tools for improved structural design and stability of helical AApeptides
December 2023
Peptidomimetics have garnered increased attention due to their unique structural properties and self-assembly, as well as their promising applications in material sciences and peptidomimetic drug design....
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Investigation of differences in the protein transport capability of homochiral nanochannels
December 2023
•DP modified membrane has a higher affinity for BSA than LP modified membrane.•Chiral nanochannel separates proteins based on H-bond differences.•Nanochannel membrane can be served as a nanoscaled chiral...
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Sequence-dependent catalysis and assembly to form peptide/Au nanoenzyme for glucose and plasma GSH detecting in cancer patients
December 2023
Metal ions play a pivotal role in regulating and determining the functions of proteins and peptides in nature. This study aims to investigate the regulatory role of metal ions in peptide assembly and...
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Thiol-5-methylene pyrrolones hydrogels with pH-tunable stress-relaxation and self-healing properties
December 2023
Hydrogels containing dynamically crosslinked networks through covalent bonds have garnered substantial attention in both academia and technology sectors. This interest stems from their impressive mechanical...
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