Recent advances in chirality sensing/recognition using supramolecular macrocycles
December 2025
Chiral sensing is crucial for understanding and controlling the biological activity of chiral molecule such as carbohydrates, amino acids, and proteins. It also plays a vital role in asymmetric synthesis,...
Zwitterionic hydrogels from material design to wound dressing applications
December 2025
Zwitterionic hydrogels, synthesized from zwitterions such as sulfobetaine, carboxybetaine, and phosphorylcholine, feature a balanced mix of positive and negative charges within the same polymer chains....
Tyrosinase inhibitors as melanoma sensitizers: Boosting therapeutic efficacy
December 2025
Melanoma therapy faces critical challenges due to melanin-mediated resistance mechanisms. The use of tyrosinase inhibitors to suppress tyrosinase activity and reduce melanogenesis, thereby sensitizing...
3D printed chitosan-based flexible electrode with antimicrobial properties for electrical stimulation therapy in wound healing
December 2025
Enhanced bioelectrical stimulation near wound sites plays a crucial role in promoting the wound healing cascade, such as, supporting regular collagen deposition, proper extracellular matrix (ECM) remodeling....
Unravelling the sensing mechanism of bis-urea macrocycle-based anion receptor: a theoretical study
December 2025
•The Bis-urea macrocycle based organic molecule serves as effective fluorometric chemosensor for SO32− anion sensing.•By using DFT and TD-DFT calculations, the hypothesized sensing mechanism of BUM...
Organic-inorganic nanocomposite organogel with double-network topology for enhanced mechanical and dielectric properties
December 2025
•Develop a sub-nanometer-scale organic-inorganic DN organogel by integrating flexible SNWs with a polymer (PtBA) matrix, drawing inspiration from the DN hydrogel toughening strategy.•The synergy of...
Ruthenium (II)-coordinated supramolecular drug self-assembly for efficient combination chemotherapy
December 2025
Combination chemotherapy has been considered a crucial approach in cancer treatment to address the limitations of traditional single-drug therapy. However, the common strategies that encapsulate therapeutic...
Fluorescent patterning via visible light-triggered dynamic diselenide exchange
December 2025
Fluorescent polymeric materials have recently gained significant attention in diverse fields, including biological imaging, luminescent sensing, encryption, and anti-counterfeiting. However, the patterning...
Recent advances of supramolecular systems in precise cancer theranostics
December 2025
Cancer remains a leading cause of death globally, with traditional treatments like surgery, chemotherapy, and radiotherapy often causing severe side effects and facing challenges due to tumor heterogeneity...
Exploring self-sorting in metallacycles: Toward advanced supramolecular systems and materials
December 2025
Supramolecular self-sorting illustrates nature’s remarkable precision, wherein molecular components selectively recognize and bind to specific partners through a delicate balance of energetic interactions...
Supramolecular self-assembly in solid-state lithium batteries: Bulk electrolyte design and interface engineering
December 2025
The development of solid-state lithium batteries (SSLBs) is pivotal to addressing the escalating global demand for advanced electrochemical energy storage systems, driven notably by electric vehicles...
Stimuli-responsive protein hydrogels: From dynamic tuning of hydrogel mechanics to shape morphing
December 2025
Protein hydrogels represent a rapidly evolving class of biomaterials with significant potential in biomedicine, soft robotics, and tissue engineering. These hydrogels are uniquely engineered from natural...
Self-Assembly of Short Peptides and DNA-Based Materials in Precision Biomedical Applications
Available online 13 November 2025
The spontaneous assembly of molecular components into highly organised and functional nanostructures through non-covalent interactions constitutes a defining aspect of advanced biomaterials design....
Supramolecular co-assembled hybrid hydrogels for antibacterial therapy
December 2024
Bacterial infections arising from antibiotic-resistant strains represent a formidable global health threat. In the realm of antibacterial therapies, supramolecular hydrogels stand out with unique advantages...
Hydrogen-bonding induced assembly of polymer-grafted nanoparticles towards photothermal antibacterial activities
December 2024
•Hydrogen-bonding interactions induce the self-assembly of polymer-grafted nanoparticles (PGNPs) in a good solvent.•The PGNP assemblies with controllable size can be obtained by regulating the concentration...
Versatile preparation of jellyfish-inspired color transition hydrogels via polymerization induced supramolecular geletion (PISG)
December 2024
Supramolecular hydrogels based on host–guest interactions constitute a class of intriguing soft matter and have attracted great attention due to their unique properties, etc. In this study, we successfully...
A self-cascade terpolymer platform for amplified chemo-chemodynamic therapy with synergistic immunogenic cell death enhancement
December 2024
Chemodynamic therapy, which relies on the generation of cytotoxic radicals, can be amplified by a nanoplatform that produces hydroxyl radicals while also compromising natural radical scavenging mechanisms....
Exploring the role of British dementia protein-2 (Bri2) and its BRICHOS domain in neurodegenerative disorders
December 2024
Protein functionality hinges on precise three-dimensional structures, while molecular chaperones orchestrate folding, proteome maintenance, and proteostasis. Recent attention has focused on BRICHOS...
Dynamic covalent bond-based materials: From construction to biomedical applications
December 2024
Dynamic covalent bonds (DCBs) have received significant interest due to their unique reversibility and stimuli-responsiveness. The introduction of DCBs provides materials with self-healing and controllable...
Phosphatidylserine-targeting bis(zinc-dipicolylamine) farnesol inhibits ATP production in cancer cells to overcome multidrug resistance
December 2024
Multidrug resistance significantly impedes the efficacy of cancer chemotherapy. Resistance often arises from the reduced cellular uptake of chemotherapeutic drugs, a process crucial for their cytotoxic...
Stretchable and self-healable lithium-ion batteries with all-in-one configuration
December 2024
•The LIB exhibits both stretchability and self-healability.•The electrolyte and electrodes form fused interfaces by the exchange of imine bond.•The LIB can supply power upon stretch or after being cut...
Optical absorption of supramolecular aggregates of vanadyl etioporphyrin-III in solutions and thin films
December 2024
Relative abundance of vanadyl etio-porphyrin-III, VO-EtioP-III, a typical geoporphyrin, reaches its maximum in solid fossil fuels (coals). This determines the interest in studying supramolecular structure...
Dynamic covalent epoxy network of hyperbranched-synergistic-supramolecular: Catalyst-free reprocessing, and application in carbon fiber composites recycling
December 2024
Plastic recycling, especially the recycling of thermosets, is a crucial step towards improving waste management and achieving economic recycling. Here, a method utilizing non-covalent supramolecular...
High-sensitivity and damage redundant detection capable gel-state [BMIM][BF4] electronic skin for aerospace applications
December 2024
Electronic skin (e-skin) holds significant potential for applications in robotics, Internet-of-things, and health monitoring. However, conventional e-skins often exhibit decreased sensitivity and delayed...
