Recent Articles

Open access

ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

Variants in ARHGAP21, encoding a Rho GTPase-activating protein, are associated with focal epilepsy and neurodevelopmental disorders

September 2026

Zilong Ye | Bingmei Li | Longshan Xie | Lingxia Fei | Xinguo Lu | Yunhua He | Jie Wang | Yongjun Chen | Weiping Liao | Yiwu Shi

Depletion of Kif13b promotes neuroinflammatory attack against myelin in an experimental autoimmune encephalomyelitis mouse model

September 2026

Jingxuan Chen | Yitong Xu | Guolin Miao | Liwen Zheng | Kaikai Lu | Wenxi Zhang | Wei Huang | Yuhui Wang | Xunde Xian

The oncogenic role of CCDC178 in intrahepatic cholangiocarcinoma through LGR4-dependent signaling and immune modulation

September 2026

Yunlu Jia | Yanli Wang | Yongxia Chen | Dayong Zheng | Wenguang Fu | Xiaochen Zhang | Yunkun Lu | Jian Ruan

Integrative analysis reveals the clinical utility of cancer-associated fibroblast-derived signature, and its implication for young-onset thyroid cancer

September 2026

Shenglong Xu | Tianyao Chu | Hongyan Chen | Jing Wang | Yufei Wang | Yaoyao Liang | Xinlei Zhang | Yan Zhao | Peng Zhang

Decoding age-stratified mutational landscapes in CNS lymphoma via genomic and survival profiling for precision oncology

September 2026

Jiawen Chen | Hongwei Liu | Qisheng Tang | Huihui Chai | Peng Wang | Ruize Zhu | Tong Chen | Tianwen Li | Zhifeng Shi

SERTAD4-AS1 suppresses pancreatic cancer progression by stabilizing SERTAD4 and inhibiting the Notch1 pathway

September 2026

Yuchen Tang | Jie Wang | Jun Yao | Haoran Li | Bin Yi | Chengqing Yu | Yijun Wei | Jian Yang | Zixiang Zhang | Jian Zhou

NLRP3 deficiency reprograms hepatic glucose metabolism but fails to ameliorate hepatic inflammation and fibrosis in the MCD model

September 2026

Yong Zou | Xiaowen Wu | Jingyi Wang | Jie Xia | Sen Zhang | Shuzhe Ding | Weina Liu | Zhengtang Qi

Integrative pan-cancer analysis identifies CCHCR1 as a prognostic biomarker and therapeutic target driving EMT in hepatocellular carcinoma via PI3K/AKT activation

September 2026

Shuting Huang | Wanqiu Li | Kaifang Wang | Yu Cai | Lirui Qian | Yiran Liu | Feng Gao | Tong Fang | Kin Yip Tam | Ou Sha

Identification of novel compound heterozygous variants of the PNPLA6 gene in Oliver-McFarlane syndrome with concomitant insulin resistance

September 2026

Ruojun Qiu | Mingming Tang | Weifen Zhu | Binghong Wang | Wenyu Li | Yongzhen Lei | Fenping Zheng

Loss of minichromosome maintenance 4 leads to early renal dysplasia and cystogenesis outcomes

September 2026

Jing Huang | Hui-Ling Xiang | Qian Yuan | Chun Zhang | Xian-Fang Meng

An autophagy-related molecule reticulon 3 functions as a novel prognostic biomarker in hepatocellular carcinoma

September 2026

Zhu Xie | Wei Wang | Peng Yu | Mingdong Zhang | Zixin Hu | Hongyan Wang

miR-27a expression during inflammatory organ injury associated with ARDS and a novel tissue-specific knockout model

September 2026

Jieun Kim | Synthea Horton | Oleg D. Makarevich | Yan Levitsky | Thu Thien Tran | In Hyuk Bang | Xiangsheng Huang | Xuebo Chen | Katherine Figarella | Xiaoyi Yuan

GBM-Dx SIGNAL: Blood transcriptomics complementing neuroimaging to differentiate glioblastoma recurrence from treatment effects

September 2026

Dan Qi | James Murchison | Ekokobe Fonkem | Jason H. Huang | Erxi Wu

Two novel murine esophageal cancer cell line models exhibiting distinct sensitivities to immunotherapy

September 2026

Jinling Zhang | Yichen Yao | Jiajia Hu | Chenyi Wu | Jiaying Chen | Yanxing Chen | Zixin Qin | Qi Zhao | Runjie Huang | Feng Wang | Yingnan Wang

Human Gordon Holmes Syndrome modeling in mice reveals essential function of RNF216 ubiquitination in spermatogenesis and male fertility

September 2026

Jeffrey M. Mann | Chao Wei | Xiaoyuan Yan | Huirong Xie | Elena Y. Demireva | Chen Chen

Translating multimodal foundation models into oncology: Toward a future where AI directs diagnosis and therapy

July 2026

Kyung Chan Park | Wonbeak Yoo

SP1 lactylation promotes endometrial cancer cell stemness via regulation of CENPL expression

July 2026

Jian Ma | Ziyu Zhang | Bo Wang | Wantong Wang | Fanfei Kong | Xiao-Xin Ma

MAFA-expressing panniculus carnosus regulates skin twitching in mice

July 2026

Junqi Jia | Xinyue Mei | Yixiu Liu | Yang Yan | Guang Yu | Lan Zhou | Changming Wang

Optimizing anti-seizure medication selection for epilepsy in EAST/SeSAME syndrome: Insights from DrugBank and STRING databases

July 2026

Lin-Yan Hu | Lin Wan | Fang Han | Yang Huang | Gang Zhu | Wen-Qi Cao | Wen He | Xiu-Yu Shi | Guang Yang | Li-Ping Zou

RAB24 maps comprehensive clinical landscapes and mediates tumor malignant progression under the epigenetic regulation of miR-30b-3p and MMP11 in clear cell renal cell carcinoma

July 2026

Fangshi Xu | Qiao Du | Gang Li | Lingyu Guo | Jiancang Ma | Zhenlong Wang

SF3B1K700E-driven transcriptional alterations in hematopoietic progenitors underlie blood cancer pathophysiology

July 2026

Mengzhu Xue | Jianhong An | Erqiang Hu | Wenjun Deng | Shanye Yin

Circulating tumor DNA predicts tumor recurrence in early-stage breast cancer: A meta-analysis

July 2026

Luke F. Moat | John G. Mayer | David S. Puthoff | Adam M. Bissonnette | Abdul R. Shour | Scott J. Hebbring | Adedayo A. Onitilo | Zhi Wen

UCH-L1 down-regulates HER2 expression and increases lapatinib sensitivity by interacting with HSP90 in HER2-positive breast cancer

July 2026

Min Zheng | Xisha Chen | Wenqiang Gan | Lei Hou | Zhongmei Zhou | Ceshi Chen | Zhenzhen Liu | Yan Cheng

Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response

July 2026

Tanya Singh | Kubra Trabzonlu | Aleksandra Spasova | Phil Stephens | David E.J. Linden | Marianne B.M. van den Bree | Michael J. Owen | Jeremy Hall | Ujjwal Neogi | Adrian J. Harwood | Yasir Ahmed Syed

Identification of a novel prognostic gene signature associated with therapeutic resistance in hepatocellular carcinoma

July 2026

Siliang Wang | Shuangshuang Wang | Xu Wang | Yuxiang Sun | Xiao Du | Dan Han | Huanyu Ni | Yun Zhu | Huilian Shi | Zhaocong Yang

Submit your paper View articles
Recent Articles Most Downloaded Articles Most Cited Articles News Call for Papers

Stay Informed

Register your interest and receive email alerts tailored to your needs. Sign up below.