Recent Articles

Open access

ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

FLCN c.1300G>A: Selective advantage in medieval France

A novel chimeric RNA RPGR-EEF1A1 enhances autophagy by interaction with the small GTPase RAB37 in a GTP-dependent manner

Loss of microbial signals reprograms endocrine microenvironments and consistently reduces RESISTIN expression in the adrenal and thyroid cells of germ-free pigs

Prochlorperazine dimaleate elicits antiproliferative activity of gastric cancer cells via inhibiting the PI3K/AKT/mTOR signaling pathway

Proteomic profiling identifies SMARCA1 as a stage-specific epigenetic regulator of colorectal cancer metastasis through MMP modulation

AP2B1, a protein involved in endocytic trafficking, is associated with congenital heart defects when mutated

Optimal combination of immune cells for predicting outcomes in ESCC patients following neoadjuvant immunochemotherapy: Results from a prospective phase II trial

Integrated analysis of tumor mechanical microenvironment-based signature reveals prognostic risk and immune landscape in endometrial carcinoma

A rare variant in TRIOBP linked to occupational noise exposure in Meniere disease

Hemilateral adipose and muscular atrophy associated with a somatic PDGFRB p.N666K variant

Progesterone and selective progesterone receptor modulator regulate tumor-associated fibroblasts in uterine leiomyomas

Queuine tRNA ribosyltransferase 1 deficiency ameliorates hepatic steatosis and atherosclerosis possibly via modulating lipogenesis

Specific RNA structures and elements in the 5′-UTR of the SARS-CoV-2 genome and subgenomic RNA are critical for its infection

Tobacco's dual genomic footprints in bladder cancer revealed by multi-omics analysis: An SBS4-like LumU-enriched signature and smoking-driven HRD-related genomic instability

Gremlin-2 inhibits hepatocellular carcinoma progression by suppressing Akt/MEK–RPL23 signaling pathway

Therapeutic resistance in cancer: lncRNAs as modulators and targets for cancer therapy

Therapeutic resistance continues to be a significant challenge in cancer treatment, often leading to tumor recurrence, metastasis, and limited therapeutic efficacy despite advancements in chemotherapy...

Variants in ARHGAP21, encoding a Rho GTPase-activating protein, are associated with focal epilepsy and neurodevelopmental disorders

Integrative analysis reveals the clinical utility of cancer-associated fibroblast-derived signature, and its implication for young-onset thyroid cancer

Decoding age-stratified mutational landscapes in CNS lymphoma via genomic and survival profiling for precision oncology

Loss of minichromosome maintenance 4 leads to early renal dysplasia and cystogenesis outcomes

An autophagy-related molecule reticulon 3 functions as a novel prognostic biomarker in hepatocellular carcinoma

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