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Recent Articles

Variants in ARHGAP21, encoding a Rho GTPase-activating protein, are associated with focal epilepsy and neurodevelopmental disorders

Depletion of Kif13b promotes neuroinflammatory attack against myelin in an experimental autoimmune encephalomyelitis mouse model

The oncogenic role of CCDC178 in intrahepatic cholangiocarcinoma through LGR4-dependent signaling and immune modulation

Integrative analysis reveals the clinical utility of cancer-associated fibroblast-derived signature, and its implication for young-onset thyroid cancer

Decoding age-stratified mutational landscapes in CNS lymphoma via genomic and survival profiling for precision oncology

SERTAD4-AS1 suppresses pancreatic cancer progression by stabilizing SERTAD4 and inhibiting the Notch1 pathway

NLRP3 deficiency reprograms hepatic glucose metabolism but fails to ameliorate hepatic inflammation and fibrosis in the MCD model

Integrative pan-cancer analysis identifies CCHCR1 as a prognostic biomarker and therapeutic target driving EMT in hepatocellular carcinoma via PI3K/AKT activation

Identification of novel compound heterozygous variants of the PNPLA6 gene in Oliver-McFarlane syndrome with concomitant insulin resistance

Loss of minichromosome maintenance 4 leads to early renal dysplasia and cystogenesis outcomes

An autophagy-related molecule reticulon 3 functions as a novel prognostic biomarker in hepatocellular carcinoma

miR-27a expression during inflammatory organ injury associated with ARDS and a novel tissue-specific knockout model

Translating multimodal foundation models into oncology: Toward a future where AI directs diagnosis and therapy

SP1 lactylation promotes endometrial cancer cell stemness via regulation of CENPL expression

MAFA-expressing panniculus carnosus regulates skin twitching in mice

Optimizing anti-seizure medication selection for epilepsy in EAST/SeSAME syndrome: Insights from DrugBank and STRING databases

RAB24 maps comprehensive clinical landscapes and mediates tumor malignant progression under the epigenetic regulation of miR-30b-3p and MMP11 in clear cell renal cell carcinoma

SF3B1K700E-driven transcriptional alterations in hematopoietic progenitors underlie blood cancer pathophysiology

Circulating tumor DNA predicts tumor recurrence in early-stage breast cancer: A meta-analysis

UCH-L1 down-regulates HER2 expression and increases lapatinib sensitivity by interacting with HSP90 in HER2-positive breast cancer

Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response

Identification of a novel prognostic gene signature associated with therapeutic resistance in hepatocellular carcinoma

APE1 inhibition-promoted pyroptosis triggers T-cell infiltration and enhances anti-tumor immunity in NSCLC

RFX3 loss disrupts non-coding RNA networks in iPSC-derived pancreatic progenitors

Cis-regulation of FAM49A by a risk variant at 2p24 contributes to the genetic susceptibility of NSCL/P

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