Recent Articles

Synergistic anti-tumor activity of ciclopirox olamine and metformin in triple-negative breast cancer

March 2026

Yakun Wu | Hui Lyu | Congcong Tan | Margaret E. Larsen | Shou-Ching Tang | Shile Huang | Bolin Liu

Hematological and neurological expressed 1-mediated anoikis resistance promotes anaplastic thyroid cancer metastasis

March 2026

Huangcan Li | Simiao Fan | Zhongqin Gong | Chunlei Nie | Jiangqi Liu | Lingbin Xue | Xianhai Zeng | Jason Ying Kuen Chan | Michael Chi Fai Tong | George Gong Chen

A comprehensive analysis of immune checkpoint receptor–ligand pairs in aortic diseases highlights the immunosuppressive roles of CD155 and CD274

March 2026

Ying Shao | Fatma Saaoud | Keman Xu | Yifan Lu | Sheng Wu | Laisel Martinez | Roberto Vazquez-Padron | Beata Kosmider | Hong Wang | Xiaofeng Yang

CTHRC1 promotes the progression of clear cell renal cell carcinoma via the PI3K/AKT/GSK3β signaling pathway

March 2026

Wei Xie | Zhouyong Fu | Thomas Skutella | Qing Jiang | Ronggui Zhang | Yuanfeng Zhang

m6A modification erased by ALKBH5 promotes tumor growth and metastasis via regulation of YAP/ZEB1 axis in NSCLC

March 2026

Dan Jin | Weihua Di | Rui Li | Shuang Shao | Jiwei Guo

Integrated genomic analysis of EDNRB common and rare variants in Hirschsprung disease

March 2026

Xiaoyu Zuo | Jinglu Zhao | Zipeng Liu | Yuxiao Yao | Dingyang Li | Xiaogang Xu | Huimin Xia | Lihua Huang | Jixiao Zeng | Yan Zhang

Molecular profiling unveils genetic complexity and identifies potential new driver mechanisms in head and neck paragangliomas

March 2026

Sara Mellid | Eduardo Caleiras | Ángel M. Martínez-Montes | Alicia Arenas | Scherezade Jiménez | María Monteagudo | Rocío Letón | Roberta Radu | Ruth Álvarez-Díaz | Ester Arroba | Alberto Diaz-Talavera | Natalia Martínez-Puente | Cristina Álvarez-Escolá | Marta Pineda | Milagros Balbín | Fátima Al-Shahrour | Cristina Rodriguez-Antona | Cristina Montero-Conde | Luis J. Leandro-García | Emiliano Honrado | Miguel Soria-Tristán | Mercedes Robledo | Alberto Cascón

TTC21B variants disrupt the left-right asymmetry and pronephric development in zebrafish

March 2026

Linxia Deng | Yuan Yang | Xiaoling Yin | Jing Yang | Yijie Duan | Kang Wang | Weicheng Duan | Yu Zhang | Bo Xiong | Jianhua Zhou

Surface glia for modeling ALS-FTD-associated mutant C9orf72 toxicity in the nervous system of Drosophila

March 2026

Yanan Wei | Brittany Anne Snow | Ciara Crowley Stevenson | Hongyu Miao | Jasdeep Kaur | Seung Gee Lee | Nam Chul Kim | Woo Jae Kim

Electrophysiological and histological study reveals hidden subclinical haploinsufficiency of Otof

March 2026

Kyu-Hee Han | Yehree Kim | Kwon Woo Kang | Ju Ang Kim | Yonghee Oh | Min Young Kim | Jin Hee Han | Bong Jik Kim | Eunyoung Yi | Byung Yoon Choi

SLC1A3 promotes survival and immune escape of pancreatic adenocarcinoma by regulating the JAK/STAT pathway

March 2026

Yihang Liu | Huimin Chang | Xiaobo Wang | Xue Zhao | Yongjun Dang | Ling Zhang | Shuai Wang

GRWD1 inhibits nucleolar stress and reduces the sensitivity of hepatocellular carcinoma to oxaliplatin

March 2026

Yuanyuan Li | Yumeng Wu | Shenghuan Zuo | Wenjing Zhao | Jibin Liu | Yilang Wang | Xiubing Zhang | Jian Xu | Feng Sun | Dianzheng Zhang | Shudong Zhu | Aiguo Shen

SRSF7 serves as a potential therapeutic target in acute myeloid leukemia

March 2026

Dantong Shang | Hongkai Zhu | Yulin Pu | Long Liang | Haodong Xu | Yue Sheng | Huifang Zhang

Hypoxia-mediated CRIP2 activation via NICD1 translocation regulates glycolysis and cell death

March 2026

Sunyoung Park | Sang-Ha Baik | Leon F. Palomera | Eunae Kim | Hark Kyun Kim | Jun-Sik Kim | Jong Ho Kim | Chanhee Kim | Thiruma V. Arumugam | Dong-Gyu Jo

Optimized Yamanaka factors combined with TERT gene therapy for enhanced anti-aging effects

March 2026

Mengmeng Jiang | Qianqian Xu | Zhengzhi Wu

Intense light mitigates hypoxia-induced right ventricular remodeling and dysfunction through reducing inflammation associated with PF4+ resident macrophages

March 2026

Dingyuan Tian | Yingzi Pan | Xiaoyue Lai | Xinyu Bao | Pan Zheng | Yan Tan | Chun Liu | Ziyang Wang | Qingyuan Yang | Yang Liu | Xiaoqin Wan | Zhihui Zhang | Fang Deng

Hypoxia-induced right ventricular (RV) remodeling and dysfunction present a significant health risk to populations experiencing prolonged hypoxic conditions. Intense light, a noninvasive and easily...

Simple gene knockout by single gene-directed multiplex CRISPR-Cpf1

March 2026

Yeon-Ju Jeong | Gyeong-Nam Kim | Jeongin Cho | Young Hoon Sung

Dystrophin protein and mRNA analyses for the molecular genetic diagnosis of dystrophinopathy: A novel deep intronic DMD variant

January 2026

Zhiying Xie | Chang Liu | Qingyue Yuan | Zhihao Xie | Meng Yu | Yun Yuan

METTL3 promotes esophageal squamous cell carcinoma progression and reduces chemosensitivity to paclitaxel through the CASP9/BIRC3-dependent apoptosis pathway

January 2026

Pengxiang Ji | Bo Wan | Minghui Gao | Shaohua Yin | Han Wu | Junjie Wang | Yuting Ma | Weihua Xu | Minghua Wang

TMEM249-mediated sperm hyperactivation is required for mouse fertility

January 2026

Xiuge Wang | Xiaochao Wei | Yaping Gao | Chunhong Yang | Qiang Jiang | Yao Xiao | Jinpeng Wang | Yaran Zhang | Zhihua Ju | Jinming Huang

Single-cell transcriptome profiling reveals altered neural crest cell dynamics and novel biomarkers in EDNRB mutant mice with Hirschsprung's disease phenotype

January 2026

Minhao Sun | Jafari Halima | Yidan Li | Jiangtian Su | Ge Yang | Jiajun Guo | Qiwen Yang | Ruihua Dang

Single-cell molecular communications and transcriptional regulatory dynamics of T cell immunotherapy in bladder cancer

January 2026

Limin Liu | Xuan Wan | Su Liu | Chenjie Yu | Hongman Xue | Jiayi Wang | Zhu Li | Kai Liu | Chun Chen | Jiajian Wang

OTX1 promotes TNBC cell proliferation and tumor growth through the ERK pathway

January 2026

Huaying Xie | Dihe Gong | Huaqiang Zhong | Jurui Luo | Liangjie Yu | Meimei Gao | Zihao Xu | Wen Yun | Yongrui Bai | Jian Sun