Recent Articles

EGFR A859S alteration may predict a better response to third-generation EGFR-TKI treatment in advanced NSCLC

January 2026

Weiping Hong | Wenfan Fu | Ya Ma | Chenxuan Wang | Yang Xu | Jiani Yin | Jiaohui Pang | Qiuxiang Ou | Hua Bao | Jincui Gu | Baoxiu Li

Exploring the role of migrasomes in myocardial injury and repair: A novel mechanism of mitochondrial quality control

November 2025

Chunnian Ren | Dawei He | Shulei Fan | Quan Wang

A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo

November 2025

Ranmal Avinash Bandara | Zhichang Peter Zhou | Ziyan Rachel Chen | Rongqi Duan | Alan Richard Davidson | Amy P. Wong | Jim Hu

Multi-omics approach reveals gene co-alterations and survival benefit in ovarian cancer patients under platinum-based adjuvant therapy

November 2025

Ning Ding | Jiahui Chen | Xiaotian Zhao | Minyi Zhu | Qiuxiang Ou | Jiaohui Pang | Luxi Ruan | Ying Zhang | Wei Sun | Xiaoxiang Chen

The effect of sodium-glucose cotransporter 2 inhibition mediated by blood metabolites in lymphocytic leukemia

November 2025

Diguang Wen | Kai Lei | Xiang Ma | Jianchuan Deng

Bulk RNA sequencing combined with single-cell RNA sequencing analysis revealed the ferroptosis immune target of osteoarthritis synovial fibroblasts

November 2025

Qian Wu | Liang Zhou | Yuan Xue | Jiaqian Wang

Investigation of the temporal distribution of anti-VEGF drugs in the retina and the correlation with the distribution of FcR isoforms

November 2025

Jicai He | Yanping Jiang | Rongqin Yang | Ziwen Lu | Zhihuan Li | Zhigang Tu

Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy

November 2025

Rodriguez-Jimenez Francisco Javier | Artero-Castro Ana | Studenovska Hana | Selles Francisca | Arteaga Claramunt Alba Maria | Brymova Anna | Jendelova Pavla | Motlik Jan | Petrovski Goran | Lytvynchuk Lyubomyr | Ardan Taras | Tichotová Lucie | Drutovič Saskia | Sharma Ruchi | Lukovic Dunja | Bharti Kapil | Erceg Slaven

A multi-omic integrative approach combining m6A-epitranscriptomic, transcriptomic, and splicing alternative events reveals potential candidates for colorectal cancer diagnosis

November 2025

Hatim Boughanem | Jesus Pilo | Alejandro Rego | Libia Ajendra Garcia-Flores | Teresa Dawid-de Vera | Francisco J. Tinahones | Gracia Maria Martin-Nuñez | Manuel Macias-González

Population-based screening of CYP17A1 Y329fs mutation carriers in the Han Chinese population

November 2025

Bing Han | Xiaoxi Zhang | Chang Liu | Hui Zhu | Wenjiao Zhu | Yue Xu | Fengxue Zhang | Kaiwen Zhang | Shuhua Xu | Jie Qiao

CMTM3 promotes adipocyte differentiation by regulating PPARγ in 3T3-L1 cells

November 2025

Yanni Zhao | Meiyu Piao | Yuankuan Li | Sung Ho Lee | Seung-Joo Nho | Yujian Jin | Chang-Yeol Yeo | Kwang Youl Lee

Role of angiogenesis-related lncRNAs in tumor microenvironment and prognosis of lung adenocarcinoma

November 2025

Lifeng Li | Yaqi Yang | Mengle Peng | Zhirui Fan | Xiaoran Duan | Ruyue Xue | Xuefeng Lv | Ming Cheng | Jie Zhao

In vivo adeno-associated virus-mediated LDLR/PCSK9 intervention for familial hypercholesterolemia

November 2025

Zeyu Han | Cheng Tan | Jianzhong Ai | Ye Zhu

A novel variant of TFAP2A in a familial case of branchio-oculo-facial syndrome: Insights from structural bioinformatics and molecular dynamics simulation

November 2025

Jingjing Zhao | Nuo Si | Ningbei Yin | Tao Song

Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis

November 2025

Jianhua Zheng | Jingqing Chen | Wensheng Zhang | Yunpeng Wu | Tongtong Qin | Yunzhi Fa | Qianyan Dong | Rui Zhang | Yefeng Qiu

Evolutionary characteristics, biochemical structure, and function impact of MSTN gene

November 2025

Rui Zhang | Yunpeng Wu | Tianqi Sun | Zhengxing Lian | Jingqing Chen | Yefeng Qiu

The same genomic variants in the first three exons of KANSL1 can be either benign or causative of Koolen-de Vries syndrome: Definition of a validation procedure

November 2025

Federica Francesca L'Erario | Giuseppe Marangi | Anna Gloria Renzi | Marina Carapelle | Paolo Niccolò Doronzio | Domizia Pasquetti | Sabrina Maietta | Elena Sonnini | Annalisa Gazzellone | Marcella Zollino

Investigation of long-term epigenetic changes in the Nr3c1 gene by neonatal valproate exposure in juvenile rats

November 2025

Eun Hye Jang | Soon Ae Kim

circ-miR-524 accelerates the growth of liver cancer cells by inducing DNA damage repair through K-RAS

November 2025

Yanan Lu | Dongdong Lu

Welander distal myopathy-associated TIA1 mutation exacerbates P-body and stress granule dynamics concomitant with nucleolar stress under oxidative stress

November 2025

Beatriz Ramos Velasco | José Alcalde | José M. Izquierdo

iPSC-based merlin-deficient Schwann cell-like spheroids as an in vitro system for studying NF2 pathogenesis

November 2025

Núria Catasús | Gemma Casals-Sendra | Miguel Torres-Martin | Inma Rosas | Bernd Kuebler | Helena Mazuelas | Emilio Amilibia | Begoña Aran | Anna Veiga | Ángel Raya | Bernat Gel | Ignacio Blanco | Eduard Serra | Meritxell Carrió | Elisabeth Castellanos

Genetics, epidemiology and management of clubfoot and related disorders

November 2025

Muhammad Umar | Liping Tong | Hongting Jin | Tamas Terebessy | Di Chen

Clubfoot, medically termed congenital talipes equinovarus (CTEV), is a prevalent musculoskeletal birth defect, affecting approximately 0.3% of all live births. This serious congenital anomaly results...

Targeting ferroptosis in cancer stem cells: A novel strategy to improve cancer treatment

November 2025

Luyao Wang | Ye Zhu | Chengying Huang | Qiuming Pan | Junxi Wang | Hongrui Li | Yudi Huang | Guozhong Yi | Zhiyong Li | Songtao Qi | Guanglong Huang | Shanqiang Qu

Ferroptosis, a distinct regulated cell death process characterized by iron retention and lipid peroxidation, plays a crucial role in the survival of cancer stem cells (CSCs), key contributors to cancer...