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ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

Exploring the role of migrasomes in myocardial injury and repair: A novel mechanism of mitochondrial quality control

November 2025

Chunnian Ren | Dawei He | Shulei Fan | Quan Wang

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A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo

November 2025

Ranmal Avinash Bandara | Zhichang Peter Zhou | Ziyan Rachel Chen | Rongqi Duan | Alan Richard Davidson | Amy P. Wong | Jim Hu

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Multi-omics approach reveals gene co-alterations and survival benefit in ovarian cancer patients under platinum-based adjuvant therapy

November 2025

Ning Ding | Jiahui Chen | Xiaotian Zhao | Minyi Zhu | Qiuxiang Ou | Jiaohui Pang | Luxi Ruan | Ying Zhang | Wei Sun | Xiaoxiang Chen

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The effect of sodium-glucose cotransporter 2 inhibition mediated by blood metabolites in lymphocytic leukemia

November 2025

Diguang Wen | Kai Lei | Xiang Ma | Jianchuan Deng

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Bone marrow mesenchymal stroma cell serves as a harbor anchoring acute B lymphoblastic leukemia cells

November 2025

Kunpeng Wu | Fen Wang | Min Shen | Xiaohui Liang | Dan Wei | Xi Zhu | Ying Qu | Xunbin Wei | Hua Jiang | Tong Chen

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Bulk RNA sequencing combined with single-cell RNA sequencing analysis revealed the ferroptosis immune target of osteoarthritis synovial fibroblasts

November 2025

Qian Wu | Liang Zhou | Yuan Xue | Jiaqian Wang

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The targeting of AKR1C1 synergizes with gefitinib via the STAT3 signaling pathway in EGFR-mutated NSCLC

November 2025

Linlin Chang | Shuzhen Wei | Xiaotian Qi | Yang Gao | Jinhua Chen | Yu Cui | Pengxing He | Wenzhou Zhang

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Investigation of the temporal distribution of anti-VEGF drugs in the retina and the correlation with the distribution of FcR isoforms

November 2025

Jicai He | Yanping Jiang | Rongqin Yang | Ziwen Lu | Zhihuan Li | Zhigang Tu

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Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy

November 2025

Rodriguez-Jimenez Francisco Javier | Artero-Castro Ana | Studenovska Hana | Selles Francisca | Arteaga Claramunt Alba Maria | Brymova Anna | Jendelova Pavla | Motlik Jan | Petrovski Goran | Lytvynchuk Lyubomyr | Ardan Taras | Tichotová Lucie | Drutovič Saskia | Sharma Ruchi | Lukovic Dunja | Bharti Kapil | Erceg Slaven

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A multi-omic integrative approach combining m6A-epitranscriptomic, transcriptomic, and splicing alternative events reveals potential candidates for colorectal cancer diagnosis

November 2025

Hatim Boughanem | Jesus Pilo | Alejandro Rego | Libia Ajendra Garcia-Flores | Teresa Dawid-de Vera | Francisco J. Tinahones | Gracia Maria Martin-Nuñez | Manuel Macias-González

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Population-based screening of CYP17A1 Y329fs mutation carriers in the Han Chinese population

November 2025

Bing Han | Xiaoxi Zhang | Chang Liu | Hui Zhu | Wenjiao Zhu | Yue Xu | Fengxue Zhang | Kaiwen Zhang | Shuhua Xu | Jie Qiao

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Genetic complexity underlies clinical heterogeneity: YWTD β-propeller mutations and second-hit modifier mutations in LRP6-related tooth agenesis and ectodermal dysplasia in human

November 2025

Xinxin Dong | Miao Yu | Zhaoyang Jia | Jinye Bai | Jing Zhang | Shengnan Ling | Limin Guan | Yi Lu | Dong Han | Xiwen Gu

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Transcriptomic analysis reveals the landscape of the shared gene network between ectopic pregnancy and early pregnancy loss

November 2025

Mengyu Jing | Ying Zhou | Shuyue Zheng | Yahui Xie | Xi Chen | Aixia Liu

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CMTM3 promotes adipocyte differentiation by regulating PPARγ in 3T3-L1 cells

November 2025

Yanni Zhao | Meiyu Piao | Yuankuan Li | Sung Ho Lee | Seung-Joo Nho | Yujian Jin | Chang-Yeol Yeo | Kwang Youl Lee

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X26nt-mediated recruitment of eIF4A2 facilitates CCND1 translation to drive endothelial cell cycle progression

November 2025

Xinghe Zhao | Xiaocui Chen | Zheyi Chen | Lisong Shen | Lingfang Zeng | Junyao Yang

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Upregulated Krüppel-like factor 5 promotes hepatocellular carcinoma progression by activating Wnt3a signaling

November 2025

Wenli Sai | Jie Yang | Liwei Qiu | Min Xu | Min Yao | Dengfu Yao

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Role of angiogenesis-related lncRNAs in tumor microenvironment and prognosis of lung adenocarcinoma

November 2025

Lifeng Li | Yaqi Yang | Mengle Peng | Zhirui Fan | Xiaoran Duan | Ruyue Xue | Xuefeng Lv | Ming Cheng | Jie Zhao

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In vivo adeno-associated virus-mediated LDLR/PCSK9 intervention for familial hypercholesterolemia

November 2025

Zeyu Han | Cheng Tan | Jianzhong Ai | Ye Zhu

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A novel variant of TFAP2A in a familial case of branchio-oculo-facial syndrome: Insights from structural bioinformatics and molecular dynamics simulation

November 2025

Jingjing Zhao | Nuo Si | Ningbei Yin | Tao Song

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Elucidating the pathogenesis of bladder cancer through single-cell chromatin accessibility and DNA methylation analysis

September 2025

Yu Xiao | Lingao Ju | Gang Wang | Wan Jin | Hongwei Peng | Zongning Zhou | Mengxue Yu | Yi Zhang | Kaiyu Qian | Xinghuan Wang

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RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish

September 2025

Ke Zhang | Botong Li | Zhiling Deng | Yong Dong | Yuanyuan Li | Bingyu Chen | Mao Lu | Liyan Wang | Xingdong Liu | Zhenhua Guo | Sizhou Huang

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Establishment and characterization of an induced pluripotent stem cell line from a Japanese cystic fibrosis patient with homozygous 1540del10 CFTR mutation

September 2025

Hitoshi Okumura | Mikio Hayashi | Hiromi Yamashita | Fumiyuki Hattori

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New genetic insights into HIV-associated neurocognitive disorder and Alzheimer's disease

September 2025

Hai Duc Nguyen | Woong-Ki Kim

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Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles

September 2025

Yehree Kim | Yoojin Chung | Ju Ang Kim | Kyu Hee Han | Kwon Woo Kang | Ngoc-Trinh Tran | Min Young Kim | Eunyoung Yi | Sangyong Jung | Bong Jik Kim | Quynh-Anh Artinian | Seth D. Koehler | Ning Pan | Tyler M. Gibson | Lars Becker | Joseph W. Goodliffe | Molly Kalker | Madeline Barnes | Luke A. Shaheen | Meghan C. Drummond | Vassili Valayannopoulos | Byung Yoon Choi

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Clinical impact of the TPM1 p.Tyr221Cys variant causing hypertrophic cardiomyopathy

September 2025

Alessio Marinelli | Giuliana Longo | Vincenzo Cirigliano | Esther Campopiano | Clementina Dugo | Luca Ghiselli | Andrea Chiampan | Gianluca Ferri | Alessandro Costa | Stefano Bonapace | Laura Lanzoni | Giulio Molon

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