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ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo

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Multi-omics approach reveals gene co-alterations and survival benefit in ovarian cancer patients under platinum-based adjuvant therapy

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The effect of sodium-glucose cotransporter 2 inhibition mediated by blood metabolites in lymphocytic leukemia

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Bone marrow mesenchymal stroma cell serves as a harbor anchoring acute B lymphoblastic leukemia cells

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The targeting of AKR1C1 synergizes with gefitinib via the STAT3 signaling pathway in EGFR-mutated NSCLC

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Investigation of the temporal distribution of anti-VEGF drugs in the retina and the correlation with the distribution of FcR isoforms

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Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy

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A multi-omic integrative approach combining m6A-epitranscriptomic, transcriptomic, and splicing alternative events reveals potential candidates for colorectal cancer diagnosis

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Elucidating the pathogenesis of bladder cancer through single-cell chromatin accessibility and DNA methylation analysis

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RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish

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Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles

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Gene-based safety evaluation of molybdenum-containing biomaterials for cardiovascular and cerebrovascular diseases

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Identification of a splice site mutation in IL2RG in a Chinese boy with X-linked severe combined immunodeficiency

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Clinical impact of the TPM1 p.Tyr221Cys variant causing hypertrophic cardiomyopathy

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Integrating spatial transcriptomics and single-cell RNA-sequencing reveals epithelial cell alterations in benign prostatic hyperplasia following finasteride treatment

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HOPX inhibits skin cutaneous melanoma growth and induces macrophage M1 polarization

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Identifying functional subtypes and common mechanisms of rheumatoid arthritis and systemic lupus erythematosus

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Gene jigsaw: Decrypting the CPAMD8 puzzle in Chinese patients with anterior segment dysgenesis

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Glial subtype-specific modulation of disease pathogenesis in Drosophila models of ALS

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Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency

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Data-informed insights into sex differences in peripheral blood mononuclear cells from single-cell transcriptomics

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