Recent Articles

Targeting TMEM16A/ANO1 inhibits the progression of BRAF mutant (V600E) melanoma through the MEK/ERK and AKT signaling pathways

November 2024

Meiyun Shi | Jiahui Wang | Xingyu Huang | Linsu Liu | Lutao Liu | Na Zhou | Xinqi Shan | Huaqun Chen

Roles of Setbp1 in developmental hematopoiesis and acute myeloid leukemia

November 2024

Fei Ao | Fan Chen | Minhong Lv | Yuming Cao | Jinfeng Xu | Jingbo Xu | Anskar Yu-Hung Leung | Qiwen Yuan | Li Wang | Bailiang He

Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis

November 2024

Giovanna Forte | Valentina Grossi | Filomena Cariola | Antonia Lucia Buonadonna | Paola Sanese | Katia De Marco | Candida Fasano | Martina Lepore Signorile | Vittoria Disciglio | Cristiano Simone

RNA binding motif protein 43 (RBM43) suppresses hepatocellular carcinoma metastasis by regulating Slug mRNA stability

November 2024

Yao Liu | Huan Feng | Qi Zhao | Xiao Liang | Ying Wang | Shuai Xiao | Suqin Shen | Jiaxue Wu

The efficacy and safety of NeuroWell antidepressant dietary supplement, Deanxit, and their combination in the treatment of mild-to-moderate depression: A randomized clinical trial

November 2024

Honglei Yin | Zhuxin Sui | Yutong Wang | Dechen Liu | Qinglu Wang | Yanchao Wang | Lei Sun | Jinfeng Li | Zhen Li | Yue Liu | Shang Guo | Wenwen Wang | Hongtao Yin | Ping Liu | Kezhong Zhang | Huaibo Zhang | Yajun Liu | Yanqiu Liu | Qiqi Zhou | Dianfang Wei | Hui Zhang | Shanshan Wang | Yaochao Ning | Shuang Geng | Xuejun Wen | Youping Deng | Hongwei Wang | Yunliang Wang

Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer

November 2024

Dingjie Wu | Si Chen | Yijin Liu | Bowen Yang | Ruixin Li | Feng Jin | Fan Yao | Yue Fang

Properdin deficiency associated with systemic meningococcal disease due to a novel p.Cys337Arg pathogenic variant

November 2024

Laura González-Sánchez | Ana Mei Agudo | Anne Van Den Rym | María Isabel Begiristain | Alazne Saizar | Rebeca Pérez de Diego | Pilar Nozal | Alberto López-Lera | Margarita López-Trascasa | Fernando Corvillo

Performance analysis of markers for prostate cell typing in single-cell data

November 2024

Yanting Shen | Xiawei Fei | Junyan Xu | Rui Yang | Qinyu Ge | Zhong Wang

CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice

November 2024

Fucheng Dong | Xiuge Wang | Tao Huang | Yingying Yin | Sai Xiao | Yanjie Ma | Huafang Wei | Bingbing Wu | Ruidan Zhang | Liying Wang | Xuejiang Guo | Fei Gao | Chao Liu | Hongbin Liu | Jianguo Zhao | Wei Li

Whole exome sequencing identifies new susceptibility candidates underlying community-acquired pneumonia

November 2024

Jacobo Pardo-Seco | Sandra Viz-Lasheras | Xabier Bello | Alberto Gómez-Carballa | Alba Camino-Mera | Sara Pischedda | María José Currás-Tuala | Irene Rivero-Calle | Ana Dacosta-Urbieta | Fernando Caamaño-Viña | Carmen Rodríguez-Tenreiro Sánchez | Isabel Cifuentes | Cristina Méndez | Chiea Chuen Khor | Federico Martinón-Torres | Antonio Salas

Effect of FTO on cardiac hypertrophy through the regulation of OBSCN expression

November 2024

Lili Chen | Yiheng Zhao | Wenjing Wang | Shuchen Zhang | Xiang Zhou

Integrated analyses reveal the prognostic and immunotherapeutic value of endoplasmic reticulum stress-related genes in cancer

November 2024

Qiuhua Lai | Lan Teng | Chengdong Liu | Yihong Lai | Jianxin Chen | Fangyao Wu | Mengduo Lei | Side Liu | Chaojun Zhu | Xiaohan Zhou

Precise and efficient insertion of A673T mutation in APP gene using MSYM

November 2024

Qing Xia | Zijie Liu | Xinyu Yang | Jiaying Xiao | Xue Zhao | Yu Zhao | Feifei Zheng | Fangliang Ge | Ke Ye | Lulu Liu | Dayong Wang | Xu Gao

Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma

November 2024

Huarong Zhang | Chaohu Wang | Jun Fan | Rongrong Guo | Qianchao Zhu | Jun Pan | Junxiang Peng | Zhiyong Wu | Songtao Qi | Yi Liu

The mucolipidosis III-causing mutation in GNPTAB, c.1760G>C, disrupts the development of somites in rats

November 2024

Tianying Nong | Jiangui Li | Xia Li | Yiqiang Li | Zhaohui Li | Weizhe Shi | Qiuchan Zhou | Hongwen Xu | Mingwei Zhu | Ya-Ping Tang

Constitutive androstane receptor: A tumor suppressor and a biomarker for favorable prognosis of liver diseases

November 2024

Sarah Da Won Bae | Romario Nguyen | Lawrence Yuen | Vincent Lam | Jacob George | Liang Qiao

The silencing transcription factor REST targets UCHL1 to regulate inflammatory response and fibrosis during cardiac hypertrophy

November 2024

Wenze Cao | Huan Liu | Ye Xu | Sangyu Hu | Yujie Yang | Li Li | Luying Peng

HJURP indicates poor prognosis of female breast cancer by promoting cell proliferation and migration

November 2024

Wenquan Chen | Hao Li | Dandan Wang | Sujin Yang | Junchen Hou | Honglei Zhou | Jinhai Tang | Jian Zhang

Simultaneous detection of methylation and genetic variations of BCR-ABL1 gene by nanopore Cas9-targeted sequencing

November 2024

Shuilian Xie | Ying Yang | Junjie Zhang | Menglin Zhu | Wang Li | Mengting Li | Yijian Chen | Hailiang Li | Weidan Lun | Weelic Chong | Shaogui Wan

Identification of immune cell infiltration pattern in diabetic nephropathy

November 2024

Yongguang Liu | Xiaoyou Liu | Ding Liu | Song Zhou | Jie Zhang | Jianmin Hu | Guorong Liao | Jun Liao | Zefeng Guo | Yuzhu Li | Siqiang Yang | Shichao Li | Hua Chen | Ying Guo | Min Li | Lipei Fan | Liuyang Li | Ming Zhao

Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor

November 2024

Shen Yang | Shixuan Zhang | Wen Zhao | Libing Fu | Li Zhang | Chan Hon Chui | Ruolan Guo | Yan Su | Dayan Sun | Huanmin Wang

GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus

November 2024

Guozhi Zhao | Piao Zhao | Yonghui Wang | Hui Zhang | Yi Zhu | Jiamin Zhong | Wulin You | Guowei Shen | Changqi Luo | Ou Mei | Xingye Wu | Jingjing Li | Yi Shu | Hongwei Wang | William Wagstaff | Hue H. Luu | Yang Bi | Lewis L. Shi | Russell R. Reid | Tong-Chuan He | Li Jiang | Wei Tang | Jiaming Fan | Ziwei Tang

Recombinant adenovirus (rAdV) is a commonly used vector system for gene transfer. Efficient initial packaging and subsequent production of rAdV remains time-consuming and labor-intensive, possibly attributable...

Focus on cardiac troponin complex: From gene expression to cardiomyopathy

November 2024

Rosetta Ragusa | Chiara Caselli

The cardiac troponin complex (cTn) is a regulatory component of sarcomere. cTn consists of three subunits: cardiac troponin C (cTnC), which confers Ca2+ sensitivity to muscle; cTnI, which inhibits the...