Impact of exercise on the 21st century epidemic of heart failure
September 2025
Heart failure (HF) poses a serious threat to public health in an aging population. HF with reduced ejection fraction (HFrEF) historically was the focus for developing prevention and management strategies,...
Two-legged medicine: Exercise-mediated health benefits
September 2025
The role of resistance training in mitigating cancer-induced cachexia: A systematic review
September 2025
Cancer induced cachexia, the involuntary loss of lean body mass and adipose tissue, is a debilitating syndrome experienced in up to 80% of all cancer patients. Cachexia is associated with poor treatment...
Episodic denervation as a driver of loss of skeletal muscle redox homeostasis and muscle weakness in sarcopenia: Possible amelioration by exercise
September 2025
Substantial reductions in muscle motor unit numbers accompany ageing and occur in parallel the age-related changes in skeletal muscle mass and fibre number. These motor unit changes are reflected in...
Exercise-induced cardioprotection: From endogenous to exogenous mechanisms
September 2025
Acute myocardial infarction (AMI) remains the leading form of cardiovascular morbidity and mortality, while exercise is a preventative and therapeutic countermeasure. The collective benefits of exercise...
Evolution of resistance training in women: History and mechanisms for health and performance
September 2025
Throughout history, cultural norms and stereotypes have discouraged resistance training in women. Today, as awareness and acceptance of resistance training in women has grown, supported by scientific...
Importance, unique aspects and guidelines, and building blocks of early childhood physical activity from a socioecological perspective
September 2025
Although the benefits of physical activity are established across all age groups, researchers have recently noted that there is uncertainty as to which correlates and determinants of physical activity...
Perspectives on enhancing human performance in the heat: Is the solution to simply “just add water”?
September 2025
Human exercise performance is influenced by factors related to inherent individual characteristics along with other modifiable factors. During exercise in the heat, sweating provides the major avenue...
Health benefits of physical activity: What role does skeletal muscle-organ crosstalk play?
September 2025
The observation that physical activity (PA) reduces the risk of coronary heart disease dates back more than 70 years ago and it is now established that regular PA reduces all-cause mortality, in part,...
Effects of amount, intensity, and mode of exercise training on the metabolic syndrome: A narrative review
September 2025
The purpose of this narrative review is to: 1) summarize findings from the three Studies of a Targeted Risk Reduction Intervention through Defined Exercise (STRRIDE) randomized trials regarding the...
Pan-cancer multi-omics analysis reveals dysregulation and prognostic significance of exercise-responsive factors
Available online 5 September 2025
Exerkines are exercise-responsive factors that contribute to systemic homeostasis and have emerging roles in tumor regulation. However, their molecular characteristics and clinical implications at the...
Impact of nutrition on long COVID
Available online 5 September 2025
Long COVID is characterised by a group of persistent symptoms following the acute SARS-COV2 infection, which presented a multifaceted challenge to the healthcare systems all over the globe. The long...
Warming up to improved performance? Effects of different specific warm-up protocols on neuromuscular performance in trained individuals
Available online 22 August 2025
This study investigated the effects of varying the set number and loads in specific warm-up (SWU) protocols on resistance training (RT) session performance....
Swimming-induced pulmonary oedema in triathletes: A narrative review of epidemiology, risk factors and prevention
Available online 21 August 2025
Swimming-induced pulmonary oedema (SIPO) has predominantly been reported in swimmers. However, to date, no review has specifically explored the scientific literature concerning the occurrence and characteristics...
Postural stability and muscle function responses to acute brisk walking in young and middle-aged women
Available online 19 August 2025
Age-related research on postural stability and muscle function responses following fatiguing tasks representative of everyday life is limited to older adults, despite the high prevalence of injurious...
Motor cortex inhibition and facilitation changes within two weeks of anterior cruciate ligament reconstruction (ACLR): A case series
Available online 19 August 2025
Anterior cruciate ligament reconstruction (ACLR) can cause arthrogenic muscle inhibition (AMI) or persistent muscle weakness that impairs physical function and return to sport. Deficits in voluntary...
Neuromotor function following lower-limb muscle or tendon injury: Systematic review and meta-analysis
Available online 6 August 2025
Alterations in neuromotor function occur following lower-limb injuries and might be a factor in recurrent injury. We evaluated if adults with previous lower-limb muscle or tendon injury demonstrate...
Brain resting state functional connectivity changes with aerobic exercise, and mindfulness: A narrative review
Available online 6 August 2025
Neuroimaging studies show that the functional connectivity of the brain changes with age. Resting state functional connectivity (rsFC) in the brain appears to decrease with aging in key networks associated...
Assessing fundamental movement skills using the Test of Gross Motor Development (TGMD): Challenges and solutions to comparability and standardization
July 2025
Proficiency in fundamental movement skills in children is linked to numerous positive physical, behavioral, and cognitive outcomes. The Test of Gross Motor Development is a widely used tool in research...
Observed relationships between nap practices, executive function, and developmental outcomes in Tunisian childcare centers
July 2025
The objective of this design was to conduct an observational study comparing anthropometric characteristics, cognitive functions, as well as gross and fine motor skills. The study included 118 preschool-aged...
Preschool-aged children 24-hour movement behaviours before and during COVID-19
July 2025
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affected health, economies, and lifestyles, but little is known about its impact...
24-h movement guidelines and its association with health-related physical fitness in Brazilian adolescents
July 2025
To examine the link between adherence to 24-h movement guidelines (isolated and combined) and muscular strength, cardiorespiratory fitness, and obesity indicators in Brazilian adolescents....
Corticospinal tract alterations after ankle sprain in adolescence: Insights from the mouse model
July 2025
Lateral ankle sprains (LAS) are associated with corticospinal pathway deficits. Existing evidence is primarily based on cross-sectional investigations and noncausal speculations. This study aims to...
Strength development following a six-week risk reduction athletic development training program in men and women
July 2025
This study retrospectively evaluated data from an athlete management system on the impact of a 6-week, 12-session risk-reduction athletic development training program on maximal isometric strength in...
Beyond physical exhaustion: Understanding overtraining syndrome through the lens of molecular mechanisms and clinical manifestation
July 2025
Overtraining Syndrome (OTS) is a condition resulting from excessive physical activity without adequate recovery, predominantly affecting elite athletes and military personnel. While overreaching can...