Engineering living root with mechanical stimulation derived from reciprocating compression in a double network hydrogel as elastic soil
June 2025
The root system actively reacts to mechanical stimuli in its environment, transmitting mechanical signals to optimize the utilization of environmental resources. While the mechanical impedance created...
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Improving the efficacy against cucumber root-knot nematode and Alleviating the phytotoxicity of fluopyram by optimizing the application method
June 2025
The root-knot nematode disease (RKN) caused by Meloidogyne incognita is a devastating threat to the production of crops, especially greenhouse vegetables. Fluopyram, a new nematicide, has been widely...
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In silico modeling and experimental validation of 2-oxoimidazolidin-4-sulfonamides as low-toxicity fungicides against Phytophthora infestans
June 2025
Phytophthora infestans control is a long-standing problem that has caused ongoing difficulties and brought limited success for over a century. Traditional methods, such as fungicides, have drawbacks...
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Discovery of novel D/L-camphor derivatives containing oxime ester as fungicide candidates: Antifungal activity, structure-activity relationship and preliminary mechanistic study
June 2025
To develop new environmentally friendly fungicides, we designed and synthesized a novel series of D/L-configured camphor oxime ester derivatives based on the natural product camphor as a lead compound....
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Melatonin—Angel of plant growth regulation and protection
June 2025
Melatonin (N-Acetyl-5-methoxytryptamine), an endogenously synthesized indoleamine, exerts pleiotropic effects in plant physiology by interacting with other phytohormones, thereby synergistically regulating...
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PDAI: A green pesticide molecule design technology platform driven by high-performance computing and artificial intelligence
June 2025
Pesticides are integral to agricultural productivity and food security. Despite the notable advancements in Computer Aided Drug Design (CADD) and Artificial Intelligence Drug Discovery (AIDD) in pharmaceuticals,...
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Science:Core regulator of rice immunity: The role of classical protein complexes on homeostasis and multipathogen resistance
June 2025
Plants have evolved complex immune networks to adapt to survival needs, and their immune mechanisms have unique regulatory patterns to cope with different environments. In rice, the maintenance of immune...
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Erucamide: A special biological control agent targeting T3SS for plant bacterial diseases
June 2025
The incidence of plant bacterial diseases has been rising annually alongside the development of facility agriculture, which can seriously affect the yield and quality of crops, and cause significant...
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Science: Pathogenic fungi exploit plant phosphate sensing via Nudix hydrolase effectors
June 2025
Inorganic phosphate (Pi) homeostasis in plants is regulated by inositol pyrophosphates (PP-InsPs), which mediate phosphate starvation responses. While beneficial microorganisms, such as arbuscular mycorrhizal...
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Optimizing role assignment for scaling innovations through AI in agricultural frameworks: An effective approach
June 2025
In the dynamic and constantly evolving world of agriculture, promoting innovation and ensuring sustainable growth are crucial. A planned division of tasks and responsibilities within agricultural systems,...
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Synthesis and insecticidal activity evaluation of sulfonamide derivatives oriented by atom replacement strategy
Available online 10 June 2025
The single-atom replacement strategy is a typical approach which just converts elements in lead compounds into their analogues with very small chemical changes. In this research, we implemented this...
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Carbonyl-bridged Trifluoromethyl Pyridine Derivatives for Pest Control and Mechanistic Investigations
Available online 6 June 2025
Trifluoromethyl pyridine (TFMP) motif is commonly discovered in structures of active pharmaceuticals. Flonicamid, characterized by the TFMP moiety, is well known as a prodrug in the knockdown of pests....
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Directed Evolution of HIS1-Like Proteins to Enhance Herbicide Metabolism in Crops
Available online 3 June 2025
HPPD (4-hydroxyphenylpyruvate dioxygenase) inhibitor are widely used in agriculture due to their high efficacy and environmental friendliness. However, many important crops, such as rice, wheat, and...
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Advances in controlled release systems for sustainable crop production: A review of nano-, micro-, and macro-formulations
Available online 27 May 2025
The high necessity to develop novel and optimized technologies for crop production is very high due to the exponential growth in term of world population of the last years. In this field a novel use...
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Antibiotics pollution in cropland and crops: A comprehensive review
Available online 18 May 2025
Production of synthetic antibiotics has rapidly expanded to meet the increasing demands in human healthcare, animal husbandry, and agriculture. Meanwhile, however, substantial quantities of untreated...
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Design, synthesis, and biological evaluation of 2-(benzylsulfonyl)-5-(2-methoxypyridin-4-yl)-1,3,4-oxadiazole derivatives as novel herbicides
Available online 13 May 2025
To develop herbicides with a novel mechanism of action, a series of 1,3,4-oxadiazolpyridine derivatives were designed and synthesized based on active substructure splicing and structure optimization....
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Mandimycin: A phospholipid-targeting natural polyene macrolide overcoming multidrug resistance in invasive fungal infections
Available online 5 May 2025
Developing novel anti-infective drugs is essential to combat antimicrobial resistance, address emerging pathogens, and safeguard global health against evolving infectious threats. A recent publication...
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A self-reportable fluorescence lighting-up nanoherbicide with minimized off-target hazards
Available online 30 April 2025
Herbicides are the most widely used class of pesticides in modern agriculture, while they are still problematic for their off-target hazards due to volatility, drift, and leaching. Nanoformulations...
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Recent developments in the synthesis of pharmacological alkyl phosphonates
March 2025
Organophosphate analogues are commonly occurring structural features that are widely present in numerous natural substances, biologically active molecules and modern pharmaceutical compounds. The development...
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The isolation, identification and efficacy of Bacillus velezensis XF-8 in tomato bacterial wilt control
March 2025
Tomato bacterial wilt is an important disease caused by Ralstonia solanacearum, which is harmful to the development of tomato industry and seriously affects the yield and quality of tomato. In this...
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Toxicological response and bioaccumulation of strontium in Triticum durum (Nachit) and Triticum aestivum (Ibtissam)
March 2025
The present study examines the toxicological effects and bioaccumulation of strontium (Sr2+) in two Moroccan wheat species, Triticum durum (Nachit) and Triticum aestivum (Ibtissam). Germination rates...
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From tryptophan to gramine: A journey into the mysterious transformation of biocatalysis
March 2025
As a natural alkaloid found extensively in cereal crops, gramine not only plays a crucial role in protecting barley and other grasses from various pests, but also reduces palatability for ruminants....
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Development of novel pyridine-based agrochemicals: A review
March 2025
Pyridine-based agrochemical products have become the most commercially successful in the 21st century. About half of the agrochemicals with pyridine scaffold were released, registered or invented only...
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Migrated silicon dioxide nanoparticles activates the rice immunity for systemic resistance against two pathogens
March 2025
Rice, the world's primary staple food, is under severe threat from several devastating diseases. To sustainably management rice diseases, developing safe, environmentally friendly alternatives urgently...
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Plants self-synthesize “agrochemical” to fight pests and diseases
March 2025
In this article, we present recent findings from a Nature Chemical Biology paper that elucidate the mechanism of crucial biosynthetic steps involved in the synthesis of steroidal glycoalkaloids (SGAs),...
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