Decoding spatiotemporal dynamics of phytohormones under stress: From subcellular visualization to wearable sensing
September 2026
Phytohormones play an important role in plant adaptation to the environment by regulating stress responses via a dynamic system. Conventional techniques used in assessing the concentrations of phytohormones...
Development and mechanism evaluation of a novel molluscicide targeting three parasitic disease intermediate hosts
September 2026
Pomacea canaliculata, Oncomelania hupensis, and Parafossarulus striatulus are gastropod species present to varying extents across the Yunnan Province. These snails are important intermediate hosts for...
A solarization-triggered fungicide controlled-release platform enabled by “carrier-in-carrier” hiberarchy for on-demand soil-borne disease defense
September 2026
Soil application of fungicides is a primary control strategy for soil-borne diseases, while soil solarization provides an economical and eco-friendly supplementary approach. Herein, we propose a novel...
Scaffold hopping in agricultural antibacterials: Research progress and prospects
September 2026
Plant bacterial diseases cause substantial economic losses in agricultural production annually. Conventional agricultural antibacterial agents, including copper-based formulations and antibiotics, exhibit...
A fluorescent sensor for non-enzymatic detection of glufosinate ammonium
September 2026
Glufosinate ammonium (GLA) ranks as the second most widely used herbicide worldwide and plays a vital role in modern agriculture. However, excessive or improper application of GLA has resulted in substantial...
Light conversion film of biodegradable cellulose composite with fluorophores doped silica nanoparticles for plant growth
September 2026
Rational manipulation of solar spectrum represents a promising strategy to enhance crop productivity and agricultural light conversion films transforming non-utilized or low-efficiency solar photons...
Advancing herbicide safeners: Integrating structure-guided design, pathway mechanism elucidation, and smart delivery
September 2026
Weeds threaten crop production, and while essential for control, they commonly cause crop damage. Herbicide safeners safeguard crops by selectively enhancing their detoxification pathways, without affecting...
Synthesis, biological activity, and acaricidal mechanism of chiral 2,4-diphenyloxazolines
September 2026
In addition to differences in effects on the target organism, chiral compounds also have different environmental behavior and even mechanisms of action in their two enantiomers. Examining the differences...
Discovery of novel plant immune-priming compounds through WRKY45 promoter-based chemical screening
September 2026
Plant activators enhance disease resistance by priming host immunity, offering a sustainable alternative or complement to conventional pesticides. To advance this field, we established a high-throughput...
Isosteric ring exchange: Design and synthesis of phenylpyrazole derivatives with insecticidal activity
September 2026
The development of novel phenylpyrazole insecticides is essential for managing pest resistance. Nicofluprole, a phenylpyrazole insecticide, serves as a valuable lead compound for structural optimization...
Nano-encapsulation of pyraclostrobin within mesoporous silica mitigates toxicity in zebrafish (Danio rerio)
September 2026
Pyraclostrobin, a widely used broad-spectrum fungicide, poses significant ecological risks to aquatic ecosystems due to its high toxicity to non-target organisms, limiting its application in paddy fields....
Design, synthesis, and evaluation of biological activity of camphor-based oxo-phenylacetamide ester compounds
September 2026
This study presents the design, synthesis, and biological evaluation of a novel series of amide derivatives based on the fenchol/bornyl scaffold. Systematic screening of biological activity revealed...
Advances in electrochemical sensing for plant health monitoring
September 2026
Plant health monitoring is becoming increasingly important for food security, precision agriculture and smart farming under the combined pressures of climate change, pathogen infection, pest infestation...
Structural basis of noncompetitive inhibition by the phenylpyrazole insecticide fipronil in an ELIC-α1 GABAAR chimera
Available online 17 September 2026
Fipronil (FIP) is a phenylpyrazole insecticide that acts as a noncompetitive pore blocker of insect type A γ-aminobutyric acid chloride channels (GABAARs). Although genetic and mutagenesis studies have...
Quinoline-Indole Hybrids as Privileged Scaffolds: Synthetic Strategies, Biological Profiles and Medicinal Potential
Available online 12 September 2026
Persistent challenges in drug discovery—multidrug resistance and complex multifactorial diseases—urgently call for innovative strategies that break free from conventional pharmacophore design. The molecular...
Distinct Cys-loop receptor-subunit dependencies underlie abamectin and fluralaner susceptibility in Drosophila melanogaster
Available online 11 September 2026
Insect Cys-loop receptors, including γ-aminobutyric acid receptors (GABAARs) and glutamate-gated chloride channels (GluCls), are major targets of neuroactive insecticides. However, the contributions...
Point mutations in β2-tubulin endow Neopestalotiopsis clavispora with resistance to carbendazim
Available online 6 September 2026
Neopestalotiopsis is one of the three genera within the Pestalotiopsis-like fungi that infect tea plants, causing severe diseases. Carbendazim (MBC) is a broad-spectrum, systemic benzimidazole fungicide...
Six simultaneous point mutations within Cyp51 confer resistance to prochloraz in Alternaria alternata
Available online 5 September 2026
Alternaria alternata causes leaf brown spot disease on tobacco and threatens the yield and quality of tobacco leaf preharvest and postharvest. Prochloraz, one member of demethylation inhibitors has...
DualNeuro: A dual-model framework for selectivity between neurotoxic insecticides and CNS drugs
Available online 2 September 2026
The insect nervous system represents a primary target for insecticide development. However, the evolutionary conservation of neural targets between insects and mammals, the off-target safety of neurotoxic...
Novel dual-effect isobavachalcone synergistic formulations for integrated management of Fusarium diseases and mycotoxin contamination in maize
Available online 29 August 2026
Fusarium spp. are critical pathogenic fungi threatening the safe production of maize (Zea mays). Their infections not only cause substantial yield losses, but also drive the accumulation of carcinogenic...
Transcending production limits: A rational platform–barrier co-design framework for next-generation dsRNA biopesticides
Available online 29 August 2026
Scalable dsRNA production is essential for RNAi-based pest control, yet production yield alone does not determine field efficacy. Environmental degradation, insufficient pest exposure, and pest-specific...
Sensitive screen-printed photoelectrochemical immunoassay based on flower-shaped ZnIn2S4 nanomaterials
Available online 29 August 2026
Cucumber mosaic virus (CMV) has seriously affected the yield of crops and caused huge economic losses. By exploring the detection methods of CMV, CMV can be detected more accurately and rapidly. The...
Balancing efficacy and safety: An optimized difenoconazole nano-formulation for managing sheath blight and minimizing residue risks in rice
Available online 26 August 2026
The development of nanoscale pesticide delivery systems has significantly enhanced pesticide bioactivity while reducing the associated toxicological risks. However, the variability in efficacy across...
Comparative mechanisms of mercury and cadmium phytotoxicity: From uptake and intracellular targets to stress signaling and remediation
Available online 25 August 2026
Mercury (Hg) and cadmium (Cd) contamination in agricultural soils severely compromises plant growth, food safety, and ecosystem stability. Although both metals inhibit plant growth and induce oxidative...
Balancing efficacy and safety: Particle size-dependent trade-off of suspension concentrate for pest control and non-target ecotoxicity
Available online 20 August 2026
The application of nanotechnology in agriculture has offered promising opportunities for nanopesticides, yet the particle size effects that govern their performance remain poorly understood, especially...