A self-reportable fluorescence lighting-up nanoherbicide with minimized off-target hazards
September 2025
Herbicides are the most widely used class of pesticides in modern agriculture, while they are still problematic for their off-target hazards due to volatility, drift, and leaching. Nanoformulations...
Mandimycin: A phospholipid-targeting natural polyene macrolide overcoming multidrug resistance in invasive fungal infections
September 2025
Developing novel anti-infective drugs is essential to combat antimicrobial resistance, address emerging pathogens, and safeguard global health against evolving infectious threats. A recent publication...
Advances in controlled release systems for sustainable crop production: A review of nano-, micro-, and macro-formulations
September 2025
The high necessity to develop novel and optimized technologies for crop production is very high due to the exponential growth in term of world population of the last years. In this field a novel use...
Small-giants in agriculture: How can nanoparticles improve cereal biofortification?
September 2025
Micronutrient deficiency is a significant global issue that results in diets lacking adequate vitamins and minerals. Low nutrient levels are primarily attributed to crops cultivated in soils with insufficient...
cAMP: the true second messenger in transcriptional auxin signaling
September 2025
Auxins were the first of the major plant hormones and played key roles in plant growth and development. Auxin triggered gene expression through several mechanisms. The canonical textbook model is that...
From cultivation to Consumption: Evaluating the effects of nano fertilizers on food quality and safety
September 2025
Nanofertilizers represent a breakthrough in sustainable agriculture, offering innovative solutions to improve nutrient efficiency, crop productivity, and environmental resilience. Engineered at the...
Nanoparticle-loaded dsRNA delivery system for pesticides: status and perspective
September 2025
The integration of RNA interference (RNAi) technology with nanotechnology shows significant potential in overcoming the limitations of traditional double-stranded RNA (dsRNA) delivery systems, thereby...
The capability of synthetic cytokinin mimics for in vitro regeneration of plants
Available online 16 September 2025
Among plant hormones, cytokinins have been extensively studied for over a century due to their central roles in regulating plant development, physiology, and environmental responses. In this study,...
Utilizing cationic liposome to co-deliver poly-siRNA and chlorantraniliprole complexes: A new strategy for overcoming insecticide resistance in Plutella xylostella (Lepidoptera: Plutellidae)
Available online 2 September 2025
The diamondback moth (Plutella xylostella) is a widely distributed pest recognized for its damaging effects on cruciferous crops and its rapid development of resistance to insecticides, particularly...
Development of biosafety pyrazole-5-sulfonamide derivatives for sustainable control of peanut stem rot
Available online 23 August 2025
Sclerotium rolfsii threatens global peanut production with 15–80 % yield losses. Fungicide resistance to SDHIs (e.g., thifluzamide) and triazoles demands novel antifungal agents. Nineteen pyrazole-5-sulfonamide...
Engineering living root with mechanical stimulation derived from reciprocating compression in a double network hydrogel as elastic soil
June 2025
The root system actively reacts to mechanical stimuli in its environment, transmitting mechanical signals to optimize the utilization of environmental resources. While the mechanical impedance created...
Improving the efficacy against cucumber root-knot nematode and Alleviating the phytotoxicity of fluopyram by optimizing the application method
June 2025
The root-knot nematode disease (RKN) caused by Meloidogyne incognita is a devastating threat to the production of crops, especially greenhouse vegetables. Fluopyram, a new nematicide, has been widely...
In silico modeling and experimental validation of 2-oxoimidazolidin-4-sulfonamides as low-toxicity fungicides against Phytophthora infestans
June 2025
Phytophthora infestans control is a long-standing problem that has caused ongoing difficulties and brought limited success for over a century. Traditional methods, such as fungicides, have drawbacks...
Discovery of novel D/L-camphor derivatives containing oxime ester as fungicide candidates: Antifungal activity, structure-activity relationship and preliminary mechanistic study
June 2025
To develop new environmentally friendly fungicides, we designed and synthesized a novel series of D/L-configured camphor oxime ester derivatives based on the natural product camphor as a lead compound....
Melatonin—Angel of plant growth regulation and protection
June 2025
Melatonin (N-Acetyl-5-methoxytryptamine), an endogenously synthesized indoleamine, exerts pleiotropic effects in plant physiology by interacting with other phytohormones, thereby synergistically regulating...
PDAI: A green pesticide molecule design technology platform driven by high-performance computing and artificial intelligence
June 2025
Pesticides are integral to agricultural productivity and food security. Despite the notable advancements in Computer Aided Drug Design (CADD) and Artificial Intelligence Drug Discovery (AIDD) in pharmaceuticals,...
Science:Core regulator of rice immunity: The role of classical protein complexes on homeostasis and multipathogen resistance
June 2025
Plants have evolved complex immune networks to adapt to survival needs, and their immune mechanisms have unique regulatory patterns to cope with different environments. In rice, the maintenance of immune...
Erucamide: A special biological control agent targeting T3SS for plant bacterial diseases
June 2025
The incidence of plant bacterial diseases has been rising annually alongside the development of facility agriculture, which can seriously affect the yield and quality of crops, and cause significant...
Science: Pathogenic fungi exploit plant phosphate sensing via Nudix hydrolase effectors
June 2025
Inorganic phosphate (Pi) homeostasis in plants is regulated by inositol pyrophosphates (PP-InsPs), which mediate phosphate starvation responses. While beneficial microorganisms, such as arbuscular mycorrhizal...
Optimizing role assignment for scaling innovations through AI in agricultural frameworks: An effective approach
June 2025
In the dynamic and constantly evolving world of agriculture, promoting innovation and ensuring sustainable growth are crucial. A planned division of tasks and responsibilities within agricultural systems,...
Phytic acid-assisted amorphization of bone mineral for improved phosphorus fertilizer efficiency
Available online 19 June 2025
Phosphorus plays an indispensable role in the food chain, yet phosphorus mineral resources are finite, underscoring the urgency for developing a closed-loop phosphorus economy. Although there have been...
Synthesis and insecticidal activity evaluation of sulfonamide derivatives oriented by atom replacement strategy
Available online 10 June 2025
The single-atom replacement strategy is a typical approach which just converts elements in lead compounds into their analogues with very small chemical changes. In this research, we implemented this...
Carbonyl-bridged trifluoromethyl pyridine derivatives for pest control and mechanistic investigations
Available online 6 June 2025
Trifluoromethyl pyridine (TFMP) motif is commonly discovered in structures of active pharmaceuticals. Flonicamid, characterized by the TFMP moiety, is well known as a prodrug in the knockdown of pests....
Directed evolution of HIS1-Like proteins to enhance herbicide metabolism in crops
Available online 3 June 2025
HPPD (4-hydroxyphenylpyruvate dioxygenase) inhibitor are widely used in agriculture due to their high efficacy and environmental friendliness. However, many important crops, such as rice, wheat, and...
Design, synthesis, and biological evaluation of 2-(benzylsulfonyl)-5-(2-methoxypyridin-4-yl)-1,3,4-oxadiazole derivatives as novel herbicides
Available online 13 May 2025
To develop herbicides with a novel mechanism of action, a series of 1,3,4-oxadiazolpyridine derivatives were designed and synthesized based on active substructure splicing and structure optimization....