The sterol regulatory transcription factor FpSR coordinates fungicide tolerance, metabolism, and virulence in Fusarium pseudograminearum
Available online 29 October 2026
The application of demethylation inhibitor (DMI) fungicides remains an important strategy for controlling Fusarium crown rot caused by Fusarium pseudograminearum, a globally important fungal pathogen...
Rational discovery of potent sulfonylureas against resistant weed incorporating highly conserved waters in the binding-site of acetohydroxyacid synthase
Available online 23 October 2026
The sulfonylureas are becoming less effective as commercial herbicides, primarily due to site-of-action mutations to their target enzyme, acetohydroxyacid synthase (AHAS). To address this problem, a...
The FkPbs2Y505C mutation drives fludioxonil resistance in Fusarium kyushuense by attenuating FkHog1 phosphorylation
Available online 23 October 2026
Fusarium head blight (FHB) is a devastating global disease of wheat caused by a diverse range of Fusarium species. Among these pathogens, Fusarium kyushuense is an important causal agent that poses...
Glyphosate resistance in Eleusine indica involves EPSPS overexpression and EiGSTF3 regulated syringin accumulation
Available online 22 October 2026
Eleusine indica is a globally prevalent and noxious agricultural weed. Long-term glyphosate selection pressure has driven the widespread evolution of high-level glyphosate resistance, which severely...
Luliconazole disrupts Fusarium ergosterol synthesis by dually blocking transcription and enzyme activity
Available online 22 October 2026
The transcription factor FgSR plays a critical role in regulating ergosterol biosynthesis in Fusarium graminearum, the primary cause of Fusarium head blight (FHB) in cereal crops. Despite its importance,...
Thiazole Sulfone/Sulfonamide Derivatives as Antifungal Agents: From Chemical Diversity to Agricultural Applications
Available online 22 October 2026
Plant pathogenic fungi cause devastating losses to global crop production, driving an urgent need for novel antifungal agents. The thiazole ring is a privileged pharmacophore in fungicide discovery,...
Development and application of bioactivity evaluation methods for melanin synthesis inhibitors in rice blast control
Available online 22 October 2026
Rice blast, caused by Magnaporthe oryzae, is one of the most important diseases affecting rice production. Melanin synthesis inhibitors (MSIs) are widely used to control this disease, and their bioactivity...
Broadleaf Weed Surface Free Energy Component-Guided Design of Vitamin E-Derived Surfactants with Tailored Molecular Weights for Enhanced Herbicide Dose Transfer
Available online 21 October 2026
Effective weed management via foliar herbicide application is severely hindered by the intrinsic incompatibility between the polar aqueous spray droplets and the predominantly nonpolar, low-surface-free-energy...
Neuropeptides regulate insecticide-evasion behaviour by modulating muscle proteins in a fruit borer
Available online 21 October 2026
Insecticide resistance in insects is a consequence of adaptive evolution. Compared to metabolic resistance mechanisms, behavioral resistance is less characterized but constitutes a key adaptation to...
Linking feeding microstructure and systemic delivery for preventive root-zone control of Megalurothrips usitatus in cowpea
Available online 17 October 2026
Megalurothrips usitatus is difficult to manage in cowpea because adults and larvae feed and oviposit in protected young tissues that are poorly covered by sprays applied after infestation. This study...
Chitin-associated biological processes: an emerging major pesticide target system
Available online 13 October 2026
Pesticide innovation has repeatedly depended on a small number of biologically productive target systems. Although numerous modes of action have been identified, relatively few biological systems have...
Novel premature termination codon mutations in histidine kinase FgOs1 confer ultrahigh fludioxonil resistance in field isolates of Fusarium graminearum
Available online 12 October 2026
Fusarium head blight (FHB), predominantly associated with infection by Fusarium graminearum, represents one of the most destructive diseases affecting wheat production worldwide. Fludioxonil, a phenylpyrrole...
Engineering plant immune receptors for programmable and broad-spectrum disease resistance
Available online 9 October 2026
Plants rely on immune receptors to perceive pathogens and activate defense responses, yet naturally evolved receptors are often constrained by limited recognition spectra, pathogen adaptation, and fitness...
Resistance risk and underlying mechanism of a novel SDHI fungicide pydiflumetofen in Fusarium verticillioides
Available online 9 October 2026
Fusarium verticillioides is a major phytopathogenic fungus that causes maize Fusarium ear rot (FER), leading to severe yield losses and mycotoxin contamination worldwide. However, no fungicide has been...
Isoxazole derivatives: Progress and perspectives in agrochemical discovery
Available online 9 October 2026
Isoxazole, a versatile five-membered nitrogen–oxygen heterocycle, has emerged as a privileged scaffold in pesticide discovery. Its distinct electronic properties and rigid structure render it an excellent...
Decoding spatiotemporal dynamics of phytohormones under stress: From subcellular visualization to wearable sensing
September 2026
Phytohormones play an important role in plant adaptation to the environment by regulating stress responses via a dynamic system. Conventional techniques used in assessing the concentrations of phytohormones...
Development and mechanism evaluation of a novel molluscicide targeting three parasitic disease intermediate hosts
September 2026
Pomacea canaliculata, Oncomelania hupensis, and Parafossarulus striatulus are gastropod species present to varying extents across the Yunnan Province. These snails are important intermediate hosts for...
A solarization-triggered fungicide controlled-release platform enabled by “carrier-in-carrier” hiberarchy for on-demand soil-borne disease defense
September 2026
Soil application of fungicides is a primary control strategy for soil-borne diseases, while soil solarization provides an economical and eco-friendly supplementary approach. Herein, we propose a novel...
Scaffold hopping in agricultural antibacterials: Research progress and prospects
September 2026
Plant bacterial diseases cause substantial economic losses in agricultural production annually. Conventional agricultural antibacterial agents, including copper-based formulations and antibiotics, exhibit...
A fluorescent sensor for non-enzymatic detection of glufosinate ammonium
September 2026
Glufosinate ammonium (GLA) ranks as the second most widely used herbicide worldwide and plays a vital role in modern agriculture. However, excessive or improper application of GLA has resulted in substantial...
Light conversion film of biodegradable cellulose composite with fluorophores doped silica nanoparticles for plant growth
September 2026
Rational manipulation of solar spectrum represents a promising strategy to enhance crop productivity and agricultural light conversion films transforming non-utilized or low-efficiency solar photons...
Advancing herbicide safeners: Integrating structure-guided design, pathway mechanism elucidation, and smart delivery
September 2026
Weeds threaten crop production, and while essential for control, they commonly cause crop damage. Herbicide safeners safeguard crops by selectively enhancing their detoxification pathways, without affecting...
Synthesis, biological activity, and acaricidal mechanism of chiral 2,4-diphenyloxazolines
September 2026
In addition to differences in effects on the target organism, chiral compounds also have different environmental behavior and even mechanisms of action in their two enantiomers. Examining the differences...
Discovery of novel plant immune-priming compounds through WRKY45 promoter-based chemical screening
September 2026
Plant activators enhance disease resistance by priming host immunity, offering a sustainable alternative or complement to conventional pesticides. To advance this field, we established a high-throughput...
Isosteric ring exchange: Design and synthesis of phenylpyrazole derivatives with insecticidal activity
September 2026
The development of novel phenylpyrazole insecticides is essential for managing pest resistance. Nicofluprole, a phenylpyrazole insecticide, serves as a valuable lead compound for structural optimization...