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ISSN: 2950-273X

Does one dose of creatine supplementation fit all?

Since the late 1990s, there has been substantial research investigating the beneficial effects of creatine supplementation on measures of muscle accretion and performance, bone structure, and brain...

Ketone bodies in exercise, health and disease: Metabolic mechanisms, pathophysiology, and therapeutic implications

Ketone bodies (KBs) are alternative metabolic fuels predominantly produced in the liver during periods of carbohydrate restriction, prolonged fasting, or ketogenic dietary intake. Beyond energy metabolism,...

Utilizing nasal breathing during aerobic exercise significantly improves respiratory performance

Nasal breathing (NB) during aerobic exercise may improve respiratory performance more effectively than utilizing combined breathing (CB)....

Biomechanical differences between habitual forefoot and rearfoot strike running: A systematic review

In recent years' research, the scientific and clinical communities have shown increased interest in the differences between foot strike patterns due to their biomechanical implications and the associated...

Effects of L-carnitine supplementation on markers of exercise-induced muscle damage in healthy adults: A systematic review and meta-analysis of randomized controlled trials

L-carnitine supplementation is purported to attenuate exercise-induced muscle damage, however, individual studies revealed mixed results. Thus, we performed a systematic review and meta-analysis of...

Effect of a high carbohydrate pre-exercise meal on metabolic and performance-related parameters in male athletes following two different strategies to improve fat utilization: An exploratory examination

The purpose of this additional examination of a larger intervention was to determine the effects of a carbohydrate-rich pre-exercise meal on metabolic and performance-related parameters in a group of...

A practical approach for complete blood count analysis following acute exercise: Capillary vs. venous blood sampling

Venipuncture is the standard technique for blood sample acquisition but requires expertise, larger volumes of blood, and can be challenging in special populations. Capillary sampling may provide an...

The role of hip abductor strengthening and the effects on running gait. A systematic review

Running-related overuse injuries (RROI) are often associated with diminished hip strength, leading to exercise-based interventions to improve hip abductor strength in runners. However, the effects of...

Effects of exercise training on prostate cancer: Current evidence and potential molecular mechanisms

Prostate cancer (PCa) is a significant health concern globally, being the most diagnosed cancer and the second leading cause of male mortality in the United States. Despite advances in treatment, exploring...

Every move counts: Acute effects of sedentary breaks on glucose and lipid metabolism in middle-aged and older adults based on a multi-level meta-analysis

Prolonged sedentary behavior contributes to impaired glucose and lipid metabolism, particularly in middle-aged and older adults who are more vulnerable to metabolic decline. However, most evidence comes...

Exercise is therapy: A cross-sectional study evaluation of the impact of exercise on affect, arousal and distress in an inpatient mental health service

Positive affect leads to improved engagement in care, decreased risk of aggressive incidents and reduced use of mechanical restraints. Exercise improves affect in the general population; however, minimal...

Exploring sleep behaviour in esports and factors associated with sleep quality

The demanding training schedules in esports can disrupt regular sleep patterns and contribute to daytime sleepiness. The present study investigated casual and competitive esports players' sleep behaviour...

Multi-scale neural homeostasis mechanisms: Insights into neurodegenerative diseases and therapeutic approaches, including exercise

Neural homeostasis plays a crucial role in enabling the nervous system to adapt to internal and external perturbations by modulating molecular activity, synaptic dynamics, and structural stability....

Are sex hormone deficiency and skeletal muscle decline related? Exploring the regulation of satellite cells and protein synthesis in menopause

The menopause is characterised by a marked reduction in ovarian sex hormones –oestradiol (E2) and progesterone. This hormonal decline has been purported to be associated with reductions in skeletal...

Precision prevention in exercise: Integrating OMICS biomarkers and artificial intelligence for injury risk assessment

Exercise injuries present a significant challenge in medicine and public health, impacting exercise performance, career longevity, and overall quality of life. While OMICS technologies such as genomics,...

Effects of different creatine monohydrate supplementation strategies and resistance-band training in untrained healthy adults (≥ 50 years of age)

The age-related reduction in lean mass, strength and functional ability is a global health concern. As a possible countermeasure, there is accumulating evidence that the combination of resistance training...

Unraveling precision exercise: A journey from efficacy to molecular insights

The swift acceleration of advances in precision medicine has attracted clinicians, health systems, and policymakers, thus leaving an indelible mark on the landscape of medical practice. The increasing...

The relationships between role strain, mental toughness and mental health amongst adolescent athletes

Adolescent athletes are required to manage numerous roles to succeed. This study examined the association of role strain and mental health symptomology and the potential mediating role of mental toughness....

Breaking boundaries: A chronology with future directions of women in exercise physiology research, centred on pregnancy

Historically, females were excluded from clinical research due to their reproductive roles, hindering medical understanding and healthcare quality. Despite guidelines promoting equal participation,...

Symptom management and lifestyle interventions for people with fibromyalgia

Fibromyalgia is a complex condition with symptoms of hyperalgesia, chronic fatigue, anxiety and depression. Treating fibromyalgia symptoms typically requires pharmacological, psychological and lifestyle...

The effect of exercise mode on inflammation markers during pregnancy: A narrative review

Excessive inflammation during pregnancy can be influenced by maternal factors (e.g., pre-pregnancy obesity, excessive gestational weight gain) and is associated with adverse pregnancy outcomes. Pro-inflammatory...

Exercise-mediated circulating metabolites for brain health

Physical exercise benefits brain health via multi-layered mechanisms, among which exercise-mediated circulating metabolites play a crucial role. These peripheral-derived factors may cross the blood-brain...

Breaking barriers: Strength training feasibility in McArdle syndrome – A systematic review

The practice of physical fitness training plays a crucial role in the management of McArdle disease (MD), a metabolic myopathy characterized by myophosphorylase deficiency, which results in the reduction...

Resistance training as a modulator of autophagy in skeletal muscle: A systematic review of molecular mechanisms and adaptive responses

Autophagy is a tightly regulated intracellular degradation process essential for maintaining skeletal muscle homeostasis, particularly under metabolic stress, such as resistance exercise. This systematic...

Barriers, facilitators, and factors influencing the perceived feasibility of family-based physical activity: The role of socioeconomic status

The facilitators and barriers to family-based physical activity, child and parent perceptions of the factors influencing their perceived feasibility of family-based physical activity, and the impact...

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