Does one dose of creatine supplementation fit all?
June 2024
Since the late 1990s, there has been substantial research investigating the beneficial effects of creatine supplementation on measures of muscle accretion and performance, bone structure, and brain...
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Effects of L-carnitine supplementation on markers of exercise-induced muscle damage in healthy adults: A systematic review and meta-analysis of randomized controlled trials
June 2025
L-carnitine supplementation is purported to attenuate exercise-induced muscle damage, however, individual studies revealed mixed results. Thus, we performed a systematic review and meta-analysis of...
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Ketone bodies in exercise, health and disease: Metabolic mechanisms, pathophysiology, and therapeutic implications
June 2025
Ketone bodies (KBs) are alternative metabolic fuels predominantly produced in the liver during periods of carbohydrate restriction, prolonged fasting, or ketogenic dietary intake. Beyond energy metabolism,...
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The effect of endurance, resistance and concurrent training on respiratory capacity of cystic fibrosis patients
June 2025
Cystic fibrosis (CF) is a multisystem disease that may affect organ systems, including the respiratory system. Exercise training provides multiple benefits for people with CF. The purpose of this study...
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Biomechanical differences between habitual forefoot and rearfoot strike running: A systematic review
December 2024
In recent years' research, the scientific and clinical communities have shown increased interest in the differences between foot strike patterns due to their biomechanical implications and the associated...
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Reticulospinal function can be measured in the tibialis anterior using the StartReact method
June 2025
The neurophysiology of dorsiflexor motor pools are highly studied, with previous work showing adaptations in corticospinal tract function, but little is known about the responsiveness of the reticulospinal...
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A practical approach for complete blood count analysis following acute exercise: Capillary vs. venous blood sampling
March 2024
Venipuncture is the standard technique for blood sample acquisition but requires expertise, larger volumes of blood, and can be challenging in special populations. Capillary sampling may provide an...
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Predicting falls from biomechanical response to balance perturbation in older adults with knee osteoarthritis, an exploratory study
June 2025
The risk of falling in people with knee osteoarthritis is greater than in asymptomatic older adults. Several biomechanical responses have been connected to poor balance in osteoarthritis, but no studies...
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A randomised comparative effectiveness trial exploring two lower-dose resistance training modalities on quality of life, functional capacity and strength in healthy, untrained community-dwelling older adults
March 2025
This study investigated whether a lower volume of once-weekly resistance training (RT) could elicit meaningful improvements in quality of life (QoL), functional capacity and strength in untrained older...
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Can the inhibition of glycogen synthase kinase 3 mimic the physiological effects of exercise on muscle and other organs?
June 2025
Regular exercise is widely recognized for its numerous health benefits, including enhancing overall well-being, reducing the risk of or alleviating symptoms from various chronic diseases, and slowing...
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Exercise-triggered cardiac remodeling: AKIP1 as a novel mediator of physiological hypertrophy
June 2025
A kinase interacting protein 1 (AKIP1) is a signal transduction junction protein that promotes physiological hypertrophy. This study aimed to investigate whether exercise induces AKIP1 to promote physiological...
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Effects of exercise training on prostate cancer: Current evidence and potential molecular mechanisms
September 2024
Prostate cancer (PCa) is a significant health concern globally, being the most diagnosed cancer and the second leading cause of male mortality in the United States. Despite advances in treatment, exploring...
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The role of hip abductor strengthening and the effects on running gait. A systematic review
March 2025
Running-related overuse injuries (RROI) are often associated with diminished hip strength, leading to exercise-based interventions to improve hip abductor strength in runners. However, the effects of...
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Unraveling precision exercise: A journey from efficacy to molecular insights
March 2024
The swift acceleration of advances in precision medicine has attracted clinicians, health systems, and policymakers, thus leaving an indelible mark on the landscape of medical practice. The increasing...
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Effect of a high carbohydrate pre-exercise meal on metabolic and performance-related parameters in male athletes following two different strategies to improve fat utilization: An exploratory examination
June 2024
The purpose of this additional examination of a larger intervention was to determine the effects of a carbohydrate-rich pre-exercise meal on metabolic and performance-related parameters in a group of...
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Breaking barriers: Strength training feasibility in McArdle syndrome – A systematic review
June 2024
The practice of physical fitness training plays a crucial role in the management of McArdle disease (MD), a metabolic myopathy characterized by myophosphorylase deficiency, which results in the reduction...
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Multi-scale neural homeostasis mechanisms: Insights into neurodegenerative diseases and therapeutic approaches, including exercise
March 2025
Neural homeostasis plays a crucial role in enabling the nervous system to adapt to internal and external perturbations by modulating molecular activity, synaptic dynamics, and structural stability....
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Symptom management and lifestyle interventions for people with fibromyalgia
December 2024
Fibromyalgia is a complex condition with symptoms of hyperalgesia, chronic fatigue, anxiety and depression. Treating fibromyalgia symptoms typically requires pharmacological, psychological and lifestyle...
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Exercise-mediated circulating metabolites for brain health
December 2024
Physical exercise benefits brain health via multi-layered mechanisms, among which exercise-mediated circulating metabolites play a crucial role. These peripheral-derived factors may cross the blood-brain...
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Exploring sleep behaviour in esports and factors associated with sleep quality
June 2025
The demanding training schedules in esports can disrupt regular sleep patterns and contribute to daytime sleepiness. The present study investigated casual and competitive esports players' sleep behaviour...
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Breaking boundaries: A chronology with future directions of women in exercise physiology research, centred on pregnancy
June 2024
Historically, females were excluded from clinical research due to their reproductive roles, hindering medical understanding and healthcare quality. Despite guidelines promoting equal participation,...
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The appetite-regulatory response to an acute session of high-intensity interval training in pre-menopausal and post-menopausal females
March 2025
Sex hormones may affect the appetite response to exercise, and menopause, characterized by their withdrawal provides an opportunity to explore their role in appetite regulation. Therefore, this study...
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The relationships between role strain, mental toughness and mental health amongst adolescent athletes
March 2024
Adolescent athletes are required to manage numerous roles to succeed. This study examined the association of role strain and mental health symptomology and the potential mediating role of mental toughness....
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The effect of exercise mode on inflammation markers during pregnancy: A narrative review
Available online 31 May 2025
Excessive inflammation during pregnancy can be influenced by maternal factors (e.g., pre-pregnancy obesity, excessive gestational weight gain) and is associated with adverse pregnancy outcomes. Pro-inflammatory...
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Environmental and personal factors that influence gym members with disabilities
December 2024
Individuals with disabilities (IWD) are at increased risk for chronic health conditions. Much of this risk can be countered through exercise, yet most IWD do not achieve enough exercise to meet recommended...
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