Does one dose of creatine supplementation fit all?
June 2024
Since the late 1990s, there has been substantial research investigating the beneficial effects of creatine supplementation on measures of muscle accretion and performance, bone structure, and brain...
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A randomised comparative effectiveness trial exploring two lower-dose resistance training modalities on quality of life, functional capacity and strength in healthy, untrained community-dwelling older adults
March 2025
This study investigated whether a lower volume of once-weekly resistance training (RT) could elicit meaningful improvements in quality of life (QoL), functional capacity and strength in untrained older...
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Biomechanical differences between habitual forefoot and rearfoot strike running: A systematic review
December 2024
In recent years' research, the scientific and clinical communities have shown increased interest in the differences between foot strike patterns due to their biomechanical implications and the associated...
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Leg muscle strength and power predict rating of perceived effort during cardiopulmonary exercise testing
March 2025
The effort required to cycle progressively intensifies during an incremental exercise test. The determinants of the perceptions of leg cycling effort have not been assessed in large samples where sufficient...
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The role of hip abductor strengthening and the effects on running gait. A systematic review
March 2025
Running-related overuse injuries (RROI) are often associated with diminished hip strength, leading to exercise-based interventions to improve hip abductor strength in runners. However, the effects of...
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A practical approach for complete blood count analysis following acute exercise: Capillary vs. venous blood sampling
March 2024
Venipuncture is the standard technique for blood sample acquisition but requires expertise, larger volumes of blood, and can be challenging in special populations. Capillary sampling may provide an...
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Multi-scale neural homeostasis mechanisms: Insights into neurodegenerative diseases and therapeutic approaches, including exercise
March 2025
Neural homeostasis plays a crucial role in enabling the nervous system to adapt to internal and external perturbations by modulating molecular activity, synaptic dynamics, and structural stability....
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Effect of a high carbohydrate pre-exercise meal on metabolic and performance-related parameters in male athletes following two different strategies to improve fat utilization: An exploratory examination
June 2024
The purpose of this additional examination of a larger intervention was to determine the effects of a carbohydrate-rich pre-exercise meal on metabolic and performance-related parameters in a group of...
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The relationships between role strain, mental toughness and mental health amongst adolescent athletes
March 2024
Adolescent athletes are required to manage numerous roles to succeed. This study examined the association of role strain and mental health symptomology and the potential mediating role of mental toughness....
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Unraveling precision exercise: A journey from efficacy to molecular insights
March 2024
The swift acceleration of advances in precision medicine has attracted clinicians, health systems, and policymakers, thus leaving an indelible mark on the landscape of medical practice. The increasing...
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Symptom management and lifestyle interventions for people with fibromyalgia
December 2024
Fibromyalgia is a complex condition with symptoms of hyperalgesia, chronic fatigue, anxiety and depression. Treating fibromyalgia symptoms typically requires pharmacological, psychological and lifestyle...
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The appetite-regulatory response to an acute session of high-intensity interval training in pre-menopausal and post-menopausal females
March 2025
Sex hormones may affect the appetite response to exercise, and menopause, characterized by their withdrawal provides an opportunity to explore their role in appetite regulation. Therefore, this study...
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Exercise-mediated circulating metabolites for brain health
December 2024
Physical exercise benefits brain health via multi-layered mechanisms, among which exercise-mediated circulating metabolites play a crucial role. These peripheral-derived factors may cross the blood-brain...
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Time spent in lifestyle activities is associated with better insulin sensitivity and physical fitness in a sedentary Mexican American male population
March 2025
Sedentary behavior is highly prevalent in modern societies and has been shown to be a major risk factor for developing diabetes and cardiovascular diseases. It is well established that physical activity...
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The interplay of leptin and the peripheral endocannabinoid system in energy homeostasis and obesity, Modulation by linoleic acid and exercise
March 2025
Obesity is a major global health epidemic. Obesity and its associated comorbidities diminish the quality of life and have negative financial impacts. Obesity is a complex disease that involves the interplay...
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Breaking boundaries: A chronology with future directions of women in exercise physiology research, centred on pregnancy
June 2024
Historically, females were excluded from clinical research due to their reproductive roles, hindering medical understanding and healthcare quality. Despite guidelines promoting equal participation,...
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Effects of exercise training on prostate cancer: Current evidence and potential molecular mechanisms
September 2024
Prostate cancer (PCa) is a significant health concern globally, being the most diagnosed cancer and the second leading cause of male mortality in the United States. Despite advances in treatment, exploring...
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Enhancing health-related fitness, self-efficacy, and quality of life in adults with physical disabilities: A 9-week community-based structured exercise and mindfulness program
September 2024
Adults with physical disabilities encounter multifaceted challenges, emphasizing the critical need to address both their physical and psychological well-being while overcoming barriers to physical active...
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Effect of habitual dietary carbohydrate on maximal fat oxidation in active but untrained humans
March 2025
Changes in macronutrient intake has been linked to specific changes in rates of fat oxidation. However previous work has typically employed short duration interventions ranging from a couple of days...
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Environmental and personal factors that influence gym members with disabilities
December 2024
Individuals with disabilities (IWD) are at increased risk for chronic health conditions. Much of this risk can be countered through exercise, yet most IWD do not achieve enough exercise to meet recommended...
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Application of the COSIAM method for muscle protein turnover and skeletal muscle mass in young females: A comparison of methods for body composition assessment
December 2024
Evaluating rates of myofibrillar protein synthesis (MyoPS) and breakdown (MyoPB) is essential for understanding muscle protein turnover, which underpins changes in skeletal muscle mass (SMM). For the...
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Breaking barriers: Strength training feasibility in McArdle syndrome – A systematic review
June 2024
The practice of physical fitness training plays a crucial role in the management of McArdle disease (MD), a metabolic myopathy characterized by myophosphorylase deficiency, which results in the reduction...
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Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder
March 2024
The aim of the present study was to investigate if physical activity and cardiorespiratory fitness influence cognition, self-control, and resilience in young people with ADHD. Fifty-four children with...
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EZH1 as a key mediator of exercise-induced H3K27me3 and H3K4me3 in mouse skeletal muscle
December 2024
Epigenetic modification is a key mechanism that enhances the response of skeletal muscle to exercise training. Exercise-induced H3K27me3, which is co-modified with H3K4me3, is crucial for gene responses...
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Resistance exercise exacerbates muscle atrophy of skeletal muscle-specific Beclin1 conditioned knockout (cKO) mice
June 2024
The autophagy-lysosome pathway is the major route for protein and organelle clearance, and the functional status of autophagy plays an important role in the performance of skeletal muscle. The functional...
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