The impact of body-mass-index on functional outcomes and bleeding volumes in patients suffering spontaneous intracerebral haemorrhage
December 2025
The association between obesity and clinical as well as radiological outcomes in patients suffering spontaneous intracerebral haemorrhage (ICH) remains unclear. The obesity paradox suggests a protective...
Novel middle meningeal artery-targeted mini-craniotomy incision and technique for treatment of chronic subdural hematoma with membranes/septations – technical note and case series
December 2025
Subdural hematomas (SDH) requiring surgery are associated with significant morbidity in elderly patients. We describe a novel technique/incision for minimizing invasiveness and duration, minimizing...
The role of D-dimer in intracerebral haemorrhage outcomes
December 2025
Activation of the coagulation and fibrinolysis system is a significant factor in secondary brain injury following spontaneous intracerebral haemorrhage (ICH). However, the relationships between plasma...
Application and future directions of brain-computer interfaces in neurological disorders: Technological advances, clinical practices, and challenges
December 2025
Brain-Computer Interfaces (BCIs) represent an innovative frontier in technology, establishing a direct link between the brain and external devices. This rapidly evolving field is increasingly recognized...
Tongji Biobank: A High-Quality Repository Integrating Multi-Dimensional Biomedical Data
December 2025
With the advancement of biotechnology and computer technology, life sciences and medical data have grown rapidly, and research paradigms have undergone revolutionary changes. Biomedical and clinical...
IRRAflow active irrigation and drainage system: A glimpse into the future of cerebrospinal fluid shunts
December 2025
Chronic hydrocephalus after subarachnoid hemorrhage may become inevitable, necessitating a permanent cerebrospinal fluid shunt. We report a 40-year-old woman with SAH and a CHESS score of 6. We implemented...
Zero-shot multi-modal large language models v.s. supervised deep learning: A comparative analysis on CT-based intracranial hemorrhage subtyping
December 2025
Comparison of responses from six multi-modal large language models on a random case, which illustrates a fracture in the patient’s left skull due to trauma, with subdural hemorrhage (SDH) evident in...
Impact of pre-existing neuroendocrine tumors on brain tissue compliance following intracerebral hemorrhage in old spontaneously hypertensive rats
December 2025
Conditions associated with mass effect, such as intracranial tumors and hemorrhagic stroke (intracerebral hemorrhage; ICH), disrupt intracranial pressure (ICP) regulation by exhausting the brain’s compliance...
Targeting mitochondrial NOX4/ROS to prevent hyperglycemia-induced hemorrhagic transformation after mechanical thrombectomy in acute ischemic stroke
December 2025
This study examines whether mitochondrial NOX4 (mtNOX4) plays a crucial role in hemorrhagic transformation (HT) after mechanical thrombectomy (MT) in acute ischemic stroke (AIS)....
Robot-Assisted surgery for primary brainstem Hemorrhage: A systematic review and Meta-Analysis
December 2025
This systematic review and meta-analysis evaluated the efficacy and safety of robot-assisted surgery for primary brainstem hemorrhage (PBSH)....
A study on the relationship between the severity of leukoaraiosis and post-thrombolytic hemorrhage in acute cerebral infarction thrombolysis patients
Available online 30 December 2025
This study aims to investigate the relationship between the severity of leukoaraiosis and post-thrombolytic cerebral hemorrhage in patients with acute cerebral infarction undergoing thrombolytic therapy....
MiRNAs to predict clinical outcome in intracerebral hemorrhage: a systematic review
Available online 22 November 2025
To summarize, the involvement of miRNAs in predicting the progression of spontaneous intracerebral hemorrhage (sICH) correlated with the clinical outcome under systematic, structured review....
ASL evaluation of cerebral microcirculation after coil embolization for aneurysmal subarachnoid hemorrhage: effects of clazosentan
Available online 19 November 2025
To evaluate the effect of continuous intravenous clazosentan on cerebral microcirculation after coil embolization for aneurysmal subarachnoid hemorrhage (aSAH) using arterial spin labeling (ASL) MR...
Research progress on risk stratification warning models for early hematoma expansion and poor outcome in intracerebral hemorrhage: A narrative review
Available online 14 November 2025
This review explores recent advances in risk stratification systems for early hematoma expansion (HE), focusing on predictive models using CTA, NCCT, radiomics, and artificial intelligence to enhance...
Perioperative sodium overload is associated with the occurrence of pulmonary complications related to clazosentan in patients with subarachnoid hemorrhage followed by obliterative management for ruptured aneurysm: A retrospective observational study
October 2025
•Delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage are influenced by elevated endothelin-1 levels.•Clazosentan, a selective ETA receptor antagonist is associated with a higher...
Ultra-early hematoma growth predicts gastrointestinal bleeding after spontaneous intracerebral hemorrhage
October 2025
Ultra-early hematoma growth (uHG) has been shown to predict hematoma expansion (HE) and poor outcomes in intracerebral hemorrhage (ICH) patients. Gastrointestinal bleeding, a severe ICH complication,...
Advancing deep learning for automated stroke detection: a review
October 2025
Stroke remains a leading cause of death and disability worldwide, necessitating improved diagnostic tools for early detection and classification. Machine learning (ML) techniques have shown promise...
Link between heart failure and stroke: a comprehensive review
October 2025
Heart failure and stroke are two major cardiovascular conditions that significantly contribute to morbidity and mortality worldwide.1 While the link between heart failure and ischemic stroke is well...
Fatal complication unveiled: analyzing intracerebral hemorrhage risk after CAR-T therapy in hematologic malignancies
October 2025
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated significant efficacy in the treatment of hematologic malignancies, yet it can lead to severe complications. Intracranial hemorrhage...
Transformer-based weakly supervised intracerebral hemorrhage segmentation using image-level labels
October 2025
The segmentation of intracerebral hemorrhage (ICH) lesions in brain CT scans is of paramount importance for the diagnosis and treatment of stroke. Given the tremendous challenge of pixel-wise annotation...
Robot-guided catheter drainage with urokinase versus craniotomy hematoma evacuation for spontaneous intracerebral hemorrhage: A retrospective study
October 2025
The management of spontaneous intracerebral hemorrhage(ICH) is a topic of debate. While craniotomy has been the traditional treatment, minimally invasive techniques like robot-guided stereotactic catheter...
Inflammatory biomarkers in patients with intracranial aneurysms
Available online 10 October 2025
Intracranial aneurysm (IA) is a serious cerebrovascular disease. This study aimed to investigate the clinical characteristics and plasma biomarkers associated with IA....
Early anticoagulation in HI-1 hemorrhagic transformation after AF-associated stroke: A randomized trial
Available online 10 October 2025
•First RCT on early DOAC use in asymptomatic hemorrhagic transformation in atrial fibrillation patients.•Early anticoagulation improved 30-day NIHSS and mRS scores without increasing severe bleeding...
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