Beneficial effects of clazosentan add-on treatment on delayed cerebral microcirculatory disturbances after aneurysmal subarachnoid hemorrhage
April 2024
This retrospective study aimed to analyze the prospectively collected data of computed tomography (CT) perfusion imaging and to examine if clazosentan add-on administration prevented post-subarachnoid...
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Fluid balance management with loop diuretics in patients with aneurysmal subarachnoid hemorrhage treated with clazosentan: A case series
April 2024
Pulmonary edema is a common complication in patients receiving clazonsentan. Here, we report our experience in managing fluid balance with loop diuretics in patients with aneurysmal subarachnoid hemorrhage...
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A case of bilateral vertebral artery dissecting aneurysms presenting with subarachnoid hemorrhage evaluated using computational fluid dynamics: Which is the rupture side?
Available online 24 April 2024
Saccular aneurysms (SAs) have been long studied in hemodynamics using computational fluid dynamics (CFD), while dissecting aneurysms (DAs) remain unclear. To estimate which side of the aneurysm ruptured,...
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Hemorrhage of the hypothalamic cavernous malformation. Clinical case of surgical treatment
Available online 24 April 2024
To study the clinical and neurologic symptoms and to determine the indications for surgical treatment of hypothalamic cavernous malformations....
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Effect of mesenchymal stem cell-derived exosomes on the inflammatory response after stroke
Available online 20 April 2024
Stroke, characterized by sudden onset and significant mortality rates, represents a critical challenge in effectively treating neuroinflammation to improve treatment efficacy. In this context, mesenchymal...
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VASP, HCLS1, MSN, and EZR: Key molecular beacons in the pathophysiology of perihematomal edema Post-Intracerebral hemorrhage
Available online 17 April 2024
•The study pinpoints VASP, HCLS1, MSN, and EZR as critical genes linked to tight junction integrity, playing significant roles in perihematomal edema following intracerebral hemorrhage.•Enhanced leukocyte...
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Quadriparesis with bilateral anterior cerebral artery infarction following subarachnoid haemorrhage due to rupture of an anterior communicating artery aneurysm: A case report with literature review
Available online 3 April 2024
Anterior cerebral artery (ACA) territory infarctions are relatively rare, accounting for 0.3 % to 4.4 % of stroke cases, with bilateral occurrences being even rarer. These infarctions can lead to quadriplegia/paresis....
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Recent trends of treatment strategies and outcomes of basal ganglia hemorrhages at a single institution
Available online 21 March 2024
The Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) Trial was designed to evaluate the minimally invasive trans-sulcal parafascicular surgery (MIPS) approach, a technique advertised...
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The function of astrocytes in cerebral infarction and potential therapeutic approaches
Available online 11 March 2024
Astrocytes, the most prevalent cells in the central nervous system, significantly contribute to the normal physiological functions of the brain. Following cerebral infarction, these astrocytes undergo...
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Increased plasma periostin concentration predicts angiographic vasospasm development in non-severe aneurysmal subarachnoid hemorrhage
February 2024
It is unknown whether plasma concentrations of a matricellular protein periostin change in association with the development of angiographic vasospasm after aneurysmal subarachnoid hemorrhage (SAH)....
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Admission triglyceride-glucose index predicts long-term mortality patients with subarachnoid hemorrhage a retrospective analysis of the MIMIC-IV database
February 2024
Objective：The triglyceride-glucose (TyG) index is an indicator for insulin resistance (IR). Several studies have validated the impact of the TyG index on cerebrovascular disease. However, the value...
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Outcomes of endovascular treatment alone or with intravenous alteplase in acute ischemic stroke Patients: A retrospective cohort study
February 2024
The aim of this study is to compare the clinical outcomes, safety, and workflow of patients who underwent endovascular treatment (EVT) alone or in combination with intravenous thrombolysis (IVT), against...
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An extensive basal ganglia hemorrhage in a preexisting neonatal asphyxiated lesion after mRNA-based SARS-CoV-2 vaccination: A fatal adult case of cerebral palsy
February 2024
Neurological adverse reactions to SARS-CoV-2 vaccines include a wide variety of central nervous system (CNS) disorders; however, the cause-and-effect relationship is unclear. Herein, we present a fatal...
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Managing Mental Disorders in Intracranial Hemorrhage (ICH) Patients: A Case Study on The Importance of Early Recognition and Intervention
February 2024
Intracranial Hemorrhage (ICH) can lead to various clinical manifestations and complications. These include mental disorders that range from impaired cognitive function to disturbances in the sensorium,...
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Outcomes of Microsurgical Resection of Low-Grade Cerebral Arteriovenous Malformations: A Prospective Observational Multicenter Study from a Low-Middle-Income Country
February 2024
To appraise the overall outcomes of microsurgical resection of low-grade arteriovenous malformations (AVMs) in a low-middle-income country....
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Impact of SARS-CoV-2 Omicron variant infection on the outcomes of patients with spontaneous intracerebral hemorrhage: A prospective cohort study
February 2024
This study aims to investigate the impact of the infection with the novel coronavirus Omicron variant on the outcomes of patients with severe spontaneous intracerebral hemorrhage....
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Falx interhemispheric subdural hematoma in a hypertensive patient with urticaria: A case report
February 2024
Falx interhemispheric subdural hematoma (FISH) is a rare subtype of subdural hematoma that occurs between the cerebral hemispheres along with falx cerebri. It represents less than 0.5% of all subdural...
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Special considerations and pitfalls for intracerebral bleeding followed COVID-19 case treated by ECMO
February 2024
COVID-19, or coronavirus infection, is an acute respiratory illness caused by the corona virus that can develop into a life-threatening form of ARDS. Extracorporeal membrane oxygenation (ECMO) is a...
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Increased plasma pigment epithelium-derived factor (PEDF) concentrations as a negative predictor of angiographic vasospasm after aneurysmal subarachnoid hemorrhage
Available online 8 February 2024
Cerebral vasospasm remains a major determinant of delayed cerebral ischemia (DCI) and poor outcomes after aneurysmal subarachnoid hemorrhage (SAH). This study was aimed to investigate if a matricellular...
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Delayed hematoma growth in a patient with thrombocytopenia
Available online 17 January 2024
Hematoma growth rarely occurs after 24 h in patients with intracerebral hemorrhage (ICH). Here we report a case with delayed hematoma growth caused by thrombocytopenia. A 68-year-old leukemia patient...
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Association between glucose-to-lymphocyte ratio and short-term mortality in critically ill subarachnoid hemorrhage patients: A retrospective cohort study
Available online 2 January 2024
We aimed to evaluate the association between admission glucose-to-lymphocyte ratio (GLR) and 28-day all-cause mortality in critically ill patients with non-traumatic SAH....
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