Hemorrhage in brain tumor – An unresolved issue
June 2022
Intratumoral hemorrhage (ITH) as a variant of intracranial hemorrhage (ICH) is a known, albeit rare, clinical entity. Hemorrhages within brain neoplasms seem to remain underreported, including angiomatous...
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Reliability of Siriraj stroke score to distinguish between hemorrhagic and ischemic stroke
March 2023
The aim of study was to establish a quick way to differentiate between hemorrhagic and ischemic stroke by using siriraj stroke score and find its specificity and sensitivity by comparing it with CT...
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Clinical treatment progress of small amounts thalamus hemorrhage
June 2021
Thalamic hemorrhage is one of deep-seating cerebral lesions. Conservative therapy is preferred to patients with minor thalamic hemorrhage, and external ventricular drainage is usually applied in patients...
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Anticoagulant-associated intracerebral hemorrhage
March 2020
Intracerebral hemorrhage (ICH) is the most dangerous complication of oral anticoagulant treatment (OAT). Up to half of patients with OAT-related ICH experience early clinical deterioration due to active...
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Behavioral tests in rodent models of stroke
December 2020
Rodents are the most widely used experimental animals in stroke research due to their similar vascular anatomy, high reproductive rates, and availability of transgenic models. However, the difficulties...
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The effect of cocaine and methamphetamine on saccular aneurysm formation and rupture: A literature review
September 2021
The pathophysiology of saccular aneurysm rupture (berry aneurysm) secondary to cocaine and methamphetamine use has been classically attributed to their effects on cerebrovasculature. We conducted a...
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Cerebral vasospasm after subarachnoid hemorrhage: Developing treatments
March 2021
Subarachnoid hemorrhage (SAH) can be devastating with high morbidity and mortality. A common sequela is cerebral vasospasm, the narrowing of cerebral blood vessels that can lead to ischemic stroke if...
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Inflammatory response in sepsis and hemorrhagic stroke
June 2023
Exaggerated/deregulated inflammatory response is a major medical problem that is often associated with bad outcomes or even the death of the patient. Sepsis and severe hemorrhagic stroke are two illustrative...
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Collaterals in ischemic stroke
March 2020
Collateral flow plays a pivotal role, both in acute and chronic phases of cerebral ischemia. Recruitment of these redundant vascular networks maintains cerebral blood flow to ischemic areas, while primary...
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A translational perspective on intracranial pressure responses following intracerebral hemorrhage in animal models
March 2021
As with ischemic and traumatic brain injury, raised intracranial pressure (ICP) is a common life-threatening complication of intracerebral hemorrhage (ICH). Elevated ICP can lead to cerebral ischemia,...
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Venous sinus thrombosis after the second jab of an mRNA-based SARS-CoV-2 vaccine
March 2022
Venous sinus thrombosis (VST) after vaccination with the mRNA-based vaccine produced by Pfizer is comparatively rare and usually occurs after the first dose. VST after the second dose has been reported...
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The relationship between COVID-19 infection and intracranial hemorrhage: A systematic review
December 2021
In addition to the deleterious effects Covid-19 has on the pulmonary and cardiovascular systems, COVID-19 can also result in damage to the nervous system. This review aims to explore current literature...
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Models of cerebral amyloid angiopathy-related intracerebral hemorrhage
December 2022
Cerebral amyloid angiopathy (CAA) is a cerebrovascular disease with vascular amyloid-β deposits and is commonly observed among the elderly. Often associated with Alzheimer’s disease, CAA is among the...
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Aphasia seven days after second dose of an mRNA-based SARS-CoV-2 vaccine
December 2021
Though rare, neurological side effects of SARS-CoV-2 vaccinations are increasingly reported. Even if the first dosage goes uncomplicated, the second dose may be complicated by severe adverse reactions...
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Crescent-shaped enhancement in cranial CT angiography: A manifestation of intracerebral hematoma expansion
June 2022
Hematoma expansion is a known predictor of poor clinical outcome in patients who suffered a spontaneous intracerebral hemorrhage (ICH). A spot sign seen on computed tomography (CT) angiography (CTA)...
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Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
March 2023
Hemorrhagic stroke (HS) is a disastrous occurrence with high mortality rates, however, there are no established treatments for this pathology. Given recent advances in stem cell therapies, concerted...
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Imaging predictors for hematoma expansion in patients with intracerebral hemorrhage: A current review
June 2020
Spontaneous intracerebral hemorrhage (ICH) is the common subtype of stroke and has a higher risk of morbidity and mortality than ischemic stroke. Early enlargement of the hematoma has been identified...
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Comparison of accuracy, sensitivity and specifity of Bahrudin score vs Siriraj score vs Gajah Mada algorithm in diagnosing type of stroke
December 2022
Rapid diagnosis is crucial for stroke patients since it is an emergency that may result in morbidity and mortality. The gold standard, which is a CT scan of the brain is not always feasible, hence,...
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Middle meningeal embolization for chronic subdural Hematoma: A case series of 7 patients and review of time course of resolution
March 2023
Chronic subdural hematoma (CSDH) is common in elderly after a mild or trivial head injury. The concern for embolization is the period to wait, as compared to immediate relief of mass effect from surgery....
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Telerehabilitation-based exercises with or without transcranial direct current stimulation for pain, motor and cognitive function in older adults with mild cognitive impairments post-stroke: A multi-arm parallel-group randomized controlled trial study protocol
September 2023
Cognitive impairments, pain, and motor dysfunction are daunting challenges for stroke survivors, clinicians, and caregivers during rehabilitation programmes. There is a dearth of studies investigating...
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The effect of atorvastatin on the blood-brain barrier biomarkers in acute intracerebral hemorrhage, a pilot clinical trial
June 2023
Prior studies have shown statins provide neuroprotection by targeting secondary brain injury pathways and regulating cytokine production. We aimed to evaluate the association between statin administration...
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The blood brain barrier in cerebral ischemic injury – Disruption and repair
March 2020
With the emergence of novel technologies and ground breaking concepts in BBB basic research in the past decades, the researchers’ attention on the critical role of blood brain barrier (BBB) integrity...
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Impact of blood component transfusions, tranexamic acid and fluids on subarachnoid hemorrhage outcomes
June 2023
For years, there have been many discussions about the optimal/beneficial threshold for transfusion of blood products in subarachnoid hemorrhage (SAH), and it remains to be established. Over the period...
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Cerebral Salt-Wasting Syndrome and Elevated Brain Natriuretic Peptide Levels caused by Minor Traumatic Brain Injury: A case report
September 2020
Hyponatremia can be caused by various conditions such as Cerebral Salt Wasting Syndrome (CSWS), Inadequate Antidiuretic Hormone Secretion (SIADH), secondary adrenal dysfunction and thyroid dysfunction....
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Falx interhemispheric subdural hematoma in a hypertensive patient with urticaria: A case report
Available online 15 August 2023
Falx interhemispheric subdural hematoma (FISH) is a rare subtype of subdural hematoma that occurs between the cerebral hemispheres along with falx cerebri. It represents less than 0.5% of all subdural...
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