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ISSN: 2589-238X

Complete basilar artery occlusion following ventriculoperitoneal shunt placement for giant aneurysm complicated by concurrent obstructive hydrocephalus: A case report

Giant aneurysms are infrequently complicated with obstructive hydrocephalus (HC), however, when concurrent, effective treatments are unestablished. There are incredibly few reports of HC due to basilar...

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Impact of blood component transfusions, tranexamic acid and fluids on subarachnoid hemorrhage outcomes

For years, there have been many discussions about the optimal/beneficial threshold for transfusion of blood products in subarachnoid hemorrhage (SAH), and it remains to be established. Over the period...

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Inflammatory response in sepsis and hemorrhagic stroke

Exaggerated/deregulated inflammatory response is a major medical problem that is often associated with bad outcomes or even the death of the patient. Sepsis and severe hemorrhagic stroke are two illustrative...

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Intra-hematoma Rosiglitazone infusion therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage in rabbits

To observe the effect of intra-hematoma Rosiglitazone (RSG) infusion therapy in treating intracerebral hemorrhage (ICH). Specifically, to explore the effects of RSG on tight junction associated proteins...

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Intracranial hemorrhage and Covid-19: A retrospective analysis of 1675 hospitalized Covid-19 Brazilian patients

•This is the first large study regarding Covid-19 associated ICH in Brazil. Findings were mostly consistent with the world literature.•The incidence of ICH in hospitalized Covid-19 patients was 1.13%,...

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Intracerebral hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report

Coronavirus disease 2019 (COVID-19) is a novel coronavirus-caused infectious acute respiratory disease that can progress to severe acute respiratory distress syndrome (ARDS). For severe cases, extracorporeal...

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Fatal subarachnoid hemorrhage after ventriculoperitoneal shunt placement to manage communicating hydrocephalus due to melanoma leptomeningeal disease

Leptomeningeal disease (LMD) is a rare, late complication of malignant cancers. In addition to causing significant neurosurgical morbidity, LMD can cause communicating hydrocephalus by disrupting the...

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The effect of atorvastatin on the blood-brain barrier biomarkers in acute intracerebral hemorrhage, a pilot clinical trial

Prior studies have shown statins provide neuroprotection by targeting secondary brain injury pathways and regulating cytokine production. We aimed to evaluate the association between statin administration...

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Intranasal administration of collagenase develops cerebral microbleeds and vascular dementia in mice: In vivo pilot study

To establish a new animal model of lobar cerebral microbleeds (CMBs), we examined whether intranasal administration of collagenase induced CMBs in young mice which did not have hypertensive pathologic...

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Free-hand bedside catheter evacuation without 3D reconstruction for extensive revascularization-associated hemorrhage after ischemic stroke

To evaluate the feasibility of free-hand bedside catheterization using axial computed tomography (CT) in patients with brain hemorrhage after ischemic revascularization....

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Detection and successful endovascular treatment for a de novo intracranial pseudoaneurysm in early phase after traumatic brain injury

Traumatic intracranial pseudoaneurysm (TIP) after head trauma is rare, but it frequently ruptures in early phase. Although early detection and prompt treatment is important, the details are still unknown....

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Pituitary apoplexy following adenoviral vector-based COVID-19 vaccination

Pituitary apoplexy (PA) may complicate the course of coronavirus disease 2019 (COVID-19), posing a potential threat to life. Among vaccines designed to prevent COVID-19, there are those adenoviral vector-based,...

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Middle meningeal embolization for chronic subdural Hematoma: A case series of 7 patients and review of time course of resolution

Chronic subdural hematoma (CSDH) is common in elderly after a mild or trivial head injury. The concern for embolization is the period to wait, as compared to immediate relief of mass effect from surgery....

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Delayed cerebral ischemia associated with surgery for pituitary macroadenomas that express elevated levels of PACAP

Delayed cerebral ischemia (DCI) and cerebral vasospasm (VS) are rare but serious post-operative complications after surgery for pituitary macroadenomas; the mechanism of which are poorly understood....

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Computational fluid dynamics using dual-layer porous media modeling to evaluate the hemodynamics of cerebral aneurysm treated with FRED: A technical note

Flow diverter (FD) implantation is increasingly performed for aneurysms that are difficult to treat with conventional endovascular therapy and direct surgery. Now, a new FD stent, the Flow-Redirection...

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Pediatric hemorrhagic stroke: A retrospective case series in Hong Kong

Non-traumatic paediatric haemorrhagic stroke (PHS) is a common cause of death in children. We aimed to delineate the aetiologies of PHS and compare the outcomes of various management approaches to improve...

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Glymphatic system and post-hemorrhagic hydrocephalus

The glymphatic system is a recently identified route for exchanging parenchyma interstitial fluid and cerebrospinal fluid along perivascular space, facilitating brain waste clearance. Glymphatic system...

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Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies

Hemorrhagic stroke (HS) is a disastrous occurrence with high mortality rates, however, there are no established treatments for this pathology. Given recent advances in stem cell therapies, concerted...

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Reliability of Siriraj stroke score to distinguish between hemorrhagic and ischemic stroke

The aim of study was to establish a quick way to differentiate between hemorrhagic and ischemic stroke by using siriraj stroke score and find its specificity and sensitivity by comparing it with CT...

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Analysis of clinical misdiagnosis literature on cerebral venous sinus thrombosis

Intracranial venous sinus thrombosis (cerebral venous sinus thrombosis, CVST) clinical manifestations and signs are often atypical, and the form of the disease is variable. With the improvement of diagnostic...

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Possible synergism of tissue plasminogen activator and neurocysticercosis leading to intracranial hemorrhage

Neurocysticercosis (NCC) remains the most common helminth infection of the human central nervous system worldwide. Patients with NCC are especially predisposed to cerebrovascular events such as acute...

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Clinical study of CT-assisted positioning and bone marking-oriented transcerebellar aspiration of brainstem hemorrhage

Sixty-three patients admitted to 5 hospitals in 2014–2020 for the treatment of severe hypertensive brainstem hemorrhage by CT-guided and bone marker-oriented transcerebellar aspiration were enrolled...

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A case of spontaneous acute subdural hematoma in Plasmodium falciparum malaria: A systematic review

Malaria is one of the most common and lethal endemic disease in tropical countries. Severe malaria can be manifested as impaired consciousness, respiratory distress, convulsions, jaundice, pulmonary...

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Managing Mental Disorders in Intracranial Hemorrhage (ICH) Patients: A Case Study on The Importance of Early Recognition and Intervention

Intracranial Hemorrhage (ICH) can lead to various clinical manifestations and complications. These include mental disorders that range from impaired cognitive function to disturbances in the sensorium,...

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