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ISSN: 2589-238X

The Progressive Frontier of Aneurysmal subarachnoid Hemorrhage: Diagnosis and treatment Advances

Aneurysmal subarachnoid hemorrhage affects 6 to 9 out of every 100,000 people annually, with a mortality rate of 35%. Many people suffer from long-term disabilities, often associated with cognitive...

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The use of bioinformatic analysis to study intracerebral hemorrhage

The integration of bioinformatics analysis into intracerebral hemorrhage (ICH)research represents a paradigm shift in our approach to understanding, diagnosing, and treating this complex neurological...

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The function of astrocytes in cerebral infarction and potential therapeutic approaches

Astrocytes, the most prevalent cells in the central nervous system, significantly contribute to the normal physiological functions of the brain. Following cerebral infarction, these astrocytes undergo...

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Increased plasma pigment epithelium-derived factor (PEDF) concentrations as a negative predictor of angiographic vasospasm after aneurysmal subarachnoid hemorrhage

Cerebral vasospasm remains a major determinant of delayed cerebral ischemia (DCI) and poor outcomes after aneurysmal subarachnoid hemorrhage (SAH). This study was aimed to investigate if a matricellular...

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Chronic subdural hematoma: Epidemiological analysis and factors associated with hematoma size – A single center experience

This study aims to analyze the profile of patients with chronic subdural hematoma (cSDH) and to verify the factors associated with hematoma size....

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Anterior cranial fossa dural arteriovenous fistula presenting with left basal ganglia hemorrhage: A case report

Anterior cranial fossa dural arteriovenous fistulas (ACF-dAVFs) usually drain into the superior sagittal sinus (SSS) via the cortical veins. More rarely, the ACF-dAVF drains posteriorly into the olfactory...

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Delayed hematoma growth in a patient with thrombocytopenia

Hematoma growth rarely occurs after 24 h in patients with intracerebral hemorrhage (ICH). Here we report a case with delayed hematoma growth caused by thrombocytopenia....

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Association between glucose-to-lymphocyte ratio and short-term mortality in critically ill subarachnoid hemorrhage patients: A retrospective cohort study

We aimed to evaluate the association between admission glucose-to-lymphocyte ratio (GLR) and 28-day all-cause mortality in critically ill patients with non-traumatic SAH....

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Assessment of causal relationships between white matter brain imaging-derived phenotypes and CSVD-mediated Stroke: Genetic correlation and Mendelian randomization

Cerebral small vessel disease (CSVD) and its associated stroke are significant contributors to mortality and long-term disability globally. Despite this, there remains a lack of established predictors...

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Activation of PARP in secondary brain injury following intracerebral haemorrhage

Intracerebral hemorrhage (ICH) represents a significant health challenge due to its high mortality and severe outcomes. Poly (ADP-ribose) polymerase (PARP) is a chromatin-associated nuclear protease,...

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Cerebrovascular disorders in patients with malignant tumors

Patients with malignant tumors face an elevated risk of cerebrovascular complications, such as intratumoral hemorrhage, tumor invasion into arterial and venous sinuses, leptomeningeal infiltration,...

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Effectiveness of 3D printing technology-assisted neuroendoscopic surgery for hypertensive intracerebral hemorrhage in primary hospitals

We aimed to investigate the clinical effectiveness of integrating 3D-printing technology with neuroendoscopy for treating hypertensive intracerebral hemorrhage (HICH)....

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No association of brain CT blend sign with functional outcomes in patients with spontaneous supratentorial intracerebral hemorrhage after craniotomy

•We found the sub-high-density region of blend sign remained in a liquid state even after a period of placement and was easily drained during the operation.•We arise a conjecture that patients with...

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Effects of glibenclamide/glyburide on stroke: Systematic review

Glibenclamide (GBC), although traditionally used to treat type 2 diabetes mellitus, has demonstrated efficacy in preventing cerebral edema in the setting of stroke, including preserving the integrity...

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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage

Spontaneous (non-traumatic) intracerebral hemorrhage (ICH) is one of the major causes of global death. The purpose of our bioinformatics analysis was to detect viable pathophysiological targets and...

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Coexistence of ruptured basilar artery perforator aneurysm undetected on initial angiogram and unruptured anterior cerebral artery saccular aneurysm: Case report and literature review

Ruptured basilar artery perforator aneurysm (BAPA) is a rare cause of subarachnoid hemorrhage (SAH) and is difficult to diagnose....

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Utilizing neuroimaging visualization technology to enhance standardized neurosurgical training for Traditional Chinese Medicine residents: A neuroanatomical education study

This study aims to address the difficulties encountered by Traditional Chinese Medicine (TCM) students in learning neuroanatomy during clinical training by utilizing neuroimaging visualization tech...

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Mixed-reality head-mounted display in cranial neurosurgery: A proof-of-concept study

Mixed-reality (MR) head-mounted displays (HMD) offer virtual augmentations registered with real objects, allowing for direct patient-centered lesion visualization. In contrast to other surgical subspecialties,...

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Immune system perspective in intracerebral hemorrhage Research: A focus on monocytes and Macrophages

Monocytes and macrophages are crucial elements of the immune system, having various roles in tissue balance, inflammation, and conditions like stroke. They exhibit significant functional diversity,...

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Step-down infusion of barbiturate improves neurofunction in a new rat model of rebleeding subarachnoid hemorrhage

Rebleeding from a ruptured aneurysm is a risk factor for fatal prognosis in subarachnoid hemorrhage (SAH). A novel barbiturate treatment, step-down infusion of barbiturate (sd-B), was previously developed;...

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Diagnostic yield of different imaging modalities in the detection rate of intracranial aneurysm remnants after microsurgical clipping – A systematic review and meta-analysis

While the long-term durability of completely clipped intracranial aneurysms (IA) is excellent, IA with remnants poses a significant risk for future re-growth with subsequent need for long-term follow-up...

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Efficacy of mechanical thrombectomy for acute ischemic stroke in primary immune thrombocytopenia patient: Case report and literature review

Primary immune thrombocytopenia (ITP) paradoxically carries a high risk of developing thrombosis. However, the efficacy of mechanical thrombectomy (MT) for acute ischemic stroke (AIS) in ITP patients...

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Rare central neurocytoma in fourth ventricle: A case report with intratumoral hemorrhage and cerebellar mutism syndrome

Central neurocytoma (CN) is a rare benign tumor usually found in the lateral and third ventricles. This report highlights an exceptional case of CN in the fourth ventricle, leading to acute hydrocephalus...

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Unilateral pupil sparing oculomotor nerve paresis with an anterior communicating artery aneurysm: A case report with literature review

An anterior communicating artery (ACoA) aneurysm causing unilateral pupil sparing oculomotor nerve paresis is highly unusual. This is, to the best of our knowledge, the second case report of its sort....

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