Recent Articles

MAFA-expressing panniculus carnosus regulates skin twitching in mice

July 2026

Junqi Jia | Xinyue Mei | Yixiu Liu | Yang Yan | Guang Yu | Lan Zhou | Changming Wang

Immune patterns of the tumor microenvironment in PD-L1+ EGFR+ HNSCC patients received anti-PD-1 and EGFR-based neoadjuvant therapy

July 2026

Yuan Zhi | Wenhao Ren | Shaoming Li | Jingjing Zheng | Jianzhong Song | Ling Gao | Keqian Zhi

Comprehensive analysis and experimental verification of the role of mitochondrial dynamics-related genes in liver hepatocellular carcinoma

May 2026

Yuchen Zhang | Jing Yuan | Ning Zhang | Yang Yang | Chang Liu | Xingyu Jiang | Yue Wu | Xingxing Ma | Yinyin Xie

MSC-EVs alleviate osteoarthritic joint pain and degeneration by suppressing IL-1β/NGF signaling

May 2026

Kristeen Ye Wen Teo | Chengming Wen | Raymond Chung Wen Wong | Wei Seong Toh

Systematic druggable genome-wide analysis to identify potential therapeutic targets for urologic diseases

May 2026

Yongwang Shi | Hongyan Chen | Xinlei Zhang | Chengliang Yin | Penghu Lian

Epigenetic insights into minimal residual disease detection in cancer

May 2026

Lingao Ju | Gang Wang | Zilin Xu | Wan Xiang | Hongwei Peng | Mengxue Yu | Shenjuan Li | Yi Zhang | Kaiyu Qian | Yu Xiao

Molecular characterization of a new R1925X point mutation mouse model for dysferlinopathy

May 2026

Camille Bouchard | Louis Despax | Joël Rousseau | Jacques P. Tremblay

PI3Kα-RAS interface disruption as a new therapeutic strategy

May 2026

Abdelhalim Azzi

Deubiquitinase USP17 negatively regulates 3T3-L1 adipocyte differentiation via HDAC1

May 2026

Yuankuan Li | Meiyu Piao | Yujian Jin | Sung Ho Lee | Kwang Youl Lee

Data-driven identification of core tumor-secreted factors associated with cachexia prevalence

May 2026

Sarah Santiloni Cury | Paula Paccielli Freire | Robson Francisco Carvalho

TNFAIP8/TIPE2 inactivation modulates extracellular matrix organization gene expression and preserves the intervertebral disc structure in mice

May 2026

Zuozhen Tian | Ken Chen | Frances S. Shofer | Srish S. Chenna | Daniel Z. Sandroni | Ling Qin | Yejia Zhang

Spatial transcriptomic characterization of the pathologic niche in a patient with pulmonary crystal-storing histiocytosis

May 2026

Yao Chen | Zhining Huang | Gaoxiang Wang | Mingsheng Wu | Xiao Chen | Xiaohui Sun | Lei Gao | Mingran Xie

DNA damage-induced nuclear STING translocation orchestrates innate immune activation and chromatin remodeling

May 2026

Yihao Wang | Zan Shen | Lingjie Li | Jianfeng Shen

A novel truncating variant in PRDM16 causes severe familial cardiomyopathy with variable clinical presentations

May 2026

Yuan Che | Lindsey Walker | Lillian Sau | Tingting Tang | Wei Li | Chao Shen | Nick Shillingford | Ramzi Bawab | Jianjun Chen | Miao Sun

CBS promotes tumor immune evasion by reducing MHC-I stability

May 2026

Yanrong Yang | Yadong Guo | Shiyu Mao | Chengyuan Dong | Zhu Yu | Xudong Yao | Bing Shen

Serum tRF-4575 may regulate osteoclast differentiation and serve as a promising biomarker for enthesitis-related arthritis diagnosis

May 2026

Jing Jin | Lingzhi Qiu | Yuting Pan | Yifan Xie | Xiaoyan Shao | Zhidan Fan | Haiguo Yu

Rare variants in NRSN2 cause non-syndromic orofacial cleft through dysregulation of TGF-β signaling

May 2026

Xiaowen Zheng | Xuqin Liang | Xiantao Wu | Qing He | Chunyan Yin | Yuhua Jiao | Yanhao Wang | Yuxia Hou | Yi Ding | Huaxiang Zhao

Identification and functional characterization of a novel nonsense mutation of CASR gene in a familial hypocalciuric hypercalcemia pedigree

May 2026

Yang Tian | Bingyang Liu | Yang Xudan | Ruojun Qiu | Zhang Shaojun | Huang Haoshu | Wu Fang | Fenping Zheng

Lactylation-driven METTL3 regulates wound healing by enhancing m6A/HNRNPA2B1/DNMT1 signaling in keratinocytes

May 2026

Xue-ting Hu | Lu-min Sui | Cheng-xiu Pu | Luo-quan Ao | Mu Yuan | Li Deng | Qing Zhao | Xiao-feng Wu | Xiang Xu

Identification and analysis of extrachromosomal circular DNAs in pancreatic islets during the early and late stages of T2DM mice

May 2026

Zhichao Li | Yue Sun | Shujun Wan | Hongwen Chu | Deguo Wang | Kun Lv | Xiang Kong | Xinming Yao

Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans

May 2026

Jiaheng Li | Bojin Zhao | Zixin Qin | Si Hoi Kou | Jia Sheng Chian | Fengxia Xiao | Huijun Lei | Stephanie Andaluz | Jun He | Siddharth Sinha | Xiaowei Mao | San Ming Wang

DNA damage repair (DDR) genes play critical roles in maintaining genome stability. However, they are prone to genetic variation, of which pathogenic variation (PV) is a predisposing factor for high...

SPP1 expression serves as a potential peripheral circulating biomarker for lung cancer prognostics and drives tumorigenesis

May 2026

Xu-Ran Zhang | Fan-Li Sun | Bing Wei | Bing-Hua Jiang

Sox11 deficiency induces paravertebral muscle injury and scoliosis via Mlxipl upregulation

May 2026

Ruohao Wu | Wenting Tang | Yu Li | Zihao Deng | Jing Zhang | Xiaojuan Li | Chunwei Cao | Liyang Liang