Recent Articles

ISSN: 2352-3042

CN: 50-1221/R

p-ISSN: 2352-4820

Epigenetic insights into cancer metastasis via lineage trans-differentiation

February 2027

Cong Zou | Caixia Xia | Hongwei Peng | Shenjuan Li | Jia Shang | Wan Xiang | Haoli Ma | Fangjin Chen | Xinyue Cao | Gang Wang

Maternal high-fat diet intake ameliorates the progression of nephritis in male lupus-prone offspring via mTOR/NFκB/arachidonic acid signaling cascade

February 2027

Shuang Liu | Matome Imai | Yasuyuki Suzuki | Takashi Sugiyama | Masaki Mogi

Endothelial-specific RIPK1 K376 mutation triggers kinase hyperactivation and embryonic lethality

February 2027

Zhuyang Wu | Lingxia Wang | Xiaoxia Wu | Ming Li | Haibing Zhang

An antibiotic-free plasmid vector platform for non-viral DNA delivery

February 2027

Dan Zhao | Zakary D. Carden | Yifei Wang | Cole S. Hudson | Perry A. Maza | Dana Cyril-Ramirez | Yong Li

Differential contribution of elastin and fibrillin-1 to the cardiovascular phenotype of a double heterozygous Marfan and Williams-Beuren syndrome mouse model

February 2027

Isaac Rodríguez-Rovira | Lize Sels | Jana Ruíz-Castro | Alba Aizpuru-Gómez | Ana Paula Dantas | Victoria Campuzano | Gustavo Egea

C1orf127 deficiency causes cardiac abnormalities by disrupting the regulation of transcription initiation and interactions with RNA-binding proteins

February 2027

Yan Chen | Cancan Yao | Kun Yu | Bangguo Wu | Yuan Zhang | Xiangyu Zhou

Deciphering the role of DOT1L germline pathogenic variants in familial serrated polyposis syndrome

February 2027

Gemma Llargués-Sistac | Yasaman Sadat Keshmiri | Irene Boluda-Luis | Jenifer Muñoz | Teresa Ocaña | Stefan Aretz | Daniel Rodríguez-Alcalde | Leticia Moreira | Sergi Castellví-Bel

A novel adenoma–carcinoma sequence- and disulfidptosis-associated gene signature for prognostic prediction and mechanistic insights in colorectal cancer

February 2027

Zhen Wang | Yirong Li | Runlin Gui | Yang Li | Yuanyuan Ren | Jie Liu | Wenzhen Shi | Yuyan Xiong

Different regulatory mechanisms of hepatitis B- and C-positive hepatocellular carcinoma by single-cell RNA sequencing

February 2027

Su-Jin Baek | Seung-Jin Park | Minho Lee | Won Park | Jong-Hwan Kim | Youngjin Shin | Ok-Hee Kim | Ho Joong Choi | Say-June Kim | Yeun-Jun Chung | Seon-Young Kim

Two novel GAA missense variants and a known VUS in pompe disease: Functional characterization and pharmacological chaperone therapy

February 2027

Yang Xia | Yue Song | Ziyue Peng | Yuhuan Meng | Shihui Yu | Xue Zhang

Multi-omics studies identified the molecular network of mitochondrial dysfunction in the pathogenesis of breast cancer

February 2027

Jinsong Liu | Xiao Guan | Liuliu Quan | Min Dou | Peng Yuan

Targeting Src/FN1 adhesion circuitry to suppress circulating tumor cell clusters and lung cancer metastasis

January 2027

Ping Lin | Jianxin Jiang | Min Wu

DIRAS2 as a key intermediate molecule joining with ferroptosis and neuronal excitation/inhibition (E/I) balance in epilepsy

January 2027

Chun Peng | Xiaoyuan Mao

Enhancing ovarian cancer immunotherapy through TAGLN2-modified CAR-T cells

January 2027

Fang Yang | Hanqi Lou | Chun Zhao | Shiwei Duan | Yongming Xia

Long-term survival following SCLC transformation after osimertinib resistance in EGFR-mutant NSCLC: Benefit from local surgical resection and osimertinib rechallenge

January 2027

Qian Zhang

Transcriptional circuits of the glioma microenvironment: FOSL2 as a master regulator of the pathological niche

January 2027

Jia'ning Zhang | Chao Guan | Zechen Wang | Lizheng Jin | Zhen Lin | Jin Wen | Guangliang Chen | Pin Guo

On-demand treatment of icatibant in a patient of hereditary angioedema with KNG1 mutation

January 2027

Wo Yao | Boyun Yang | Huiying Wang

A novel causative LMNA variant in acrogeria syndrome and literature review of genotype–phenotype correlations

January 2027

Haisheng Huang | Yingying Miao | Yumeng Wang | Rui Lei | Mo Zhang | Cheng Zhang | Xianwei Cao | Ming Li | Yunqing Ren

Splice rescue of protein-truncating variants is associated with reduced selection pressure and attenuated disease phenotypes

January 2027

Xi Cheng | Fei Liu | Yixuan Gai | Lina Zhao | Wen Wen | Xueqing Lu | Zhihong Wu | Jianguo Zhang | Sen Zhao | Nan Wu

Ginsenoside Rg1 attenuates mitochondrial dysfunction in bleomycin-induced pulmonary fibrosis by inhibiting Nrf2/Sirt3 pathways

January 2027

Qi Qi | Shihao Wen | Linchao Niu | Ru Zhang | Meili Lu | Jingliang Zhang | Hongxin Wang

Robust prediction of response to growth hormone therapy by five PBMC-based transcripts

January 2027

Valerie van Kekem | Irene Victoria Bermúdez-Pérez | Alexandra E. Kulle | Maik Welzel | Nadine Hornig | Gerhard Binder | Matthias Hübenthal | Robert Häsler | Paul-Martin Holterhus

The ATG4 isotype is a key regulator in CSE/H2S-mediated mitophagy in cardiac hypertrophy

January 2027

Yijun Xin | Zhaoji Yuan | Yong Zhang | Xiaofei Qiao | Xiangdong Wang | Siying Li

Targeting nucleolin-driven cancer stemness suppresses high-risk neuroblastoma in vivo

January 2027

Dan Qi | Ronghu Ke | Euni Wu | Yizhong Pan | S. Stephen Yi | Jason H. Huang | Erxi Wu

TfR1 deficiency beyond combined immunodeficiency. Pivotal role of mitochondrial function and iron-sulfur cluster biogenesis in disease pathogenesis

January 2027

Gerard Muñoz-Pujol | Elise J. Huisman | Juan-Francisco Mesa | Marieke Joosten | Annick Devos | Miguel Fernandez-Burriel | Olatz Ugarteburu | Eulàlia Segur-Bailach | Sabrina Gea-Sorlí | Sonia Moliner | Laia Farré-Tarrats | Mariona Guitart-Mampel | Gianluca Arauz-Garofalo | Marina Gay | Neus Villamor | Gemma Martín | María Calvo | Gloria Garrabou | María J. Macias | Laura Gort | Judit García-Villoria | Cristina Fillat | Frederic Tort | Antonia Ribes

Clinical and iPSC-based characterization of the HNF1A p.T82M variant

January 2027

Ran Liu | Aysha Bakari Murusuri | Siyi Huang | Zhe Dai | Wei Jiang | Jun Tang

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