Recent Articles

ISSN: 2352-3042

CN: 50-1221/R

p-ISSN: 2352-4820

Variants in ARHGAP21, encoding a Rho GTPase-activating protein, are associated with focal epilepsy and neurodevelopmental disorders

September 2026

Zilong Ye | Bingmei Li | Longshan Xie | Lingxia Fei | Xinguo Lu | Yunhua He | Jie Wang | Yongjun Chen | Weiping Liao | Yiwu Shi

Depletion of Kif13b promotes neuroinflammatory attack against myelin in an experimental autoimmune encephalomyelitis mouse model

September 2026

Jingxuan Chen | Yitong Xu | Guolin Miao | Liwen Zheng | Kaikai Lu | Wenxi Zhang | Wei Huang | Yuhui Wang | Xunde Xian

The oncogenic role of CCDC178 in intrahepatic cholangiocarcinoma through LGR4-dependent signaling and immune modulation

September 2026

Yunlu Jia | Yanli Wang | Yongxia Chen | Dayong Zheng | Wenguang Fu | Xiaochen Zhang | Yunkun Lu | Jian Ruan

Translating multimodal foundation models into oncology: Toward a future where AI directs diagnosis and therapy

July 2026

Kyung Chan Park | Wonbeak Yoo

SP1 lactylation promotes endometrial cancer cell stemness via regulation of CENPL expression

July 2026

Jian Ma | Ziyu Zhang | Bo Wang | Wantong Wang | Fanfei Kong | Xiao-Xin Ma

MAFA-expressing panniculus carnosus regulates skin twitching in mice

July 2026

Junqi Jia | Xinyue Mei | Yixiu Liu | Yang Yan | Guang Yu | Lan Zhou | Changming Wang

Renal adverse events in EGFR-TKI treatment: Comprehensive characterization of clinical patterns and molecular underpinnings

July 2026

Huili Xiao | Anqi Lin | Wentao Xu | Junyi Shen | Cuiying Chen | Jian Zhang | Ting Wei | Peng Luo

Optimizing anti-seizure medication selection for epilepsy in EAST/SeSAME syndrome: Insights from DrugBank and STRING databases

July 2026

Lin-Yan Hu | Lin Wan | Fang Han | Yang Huang | Gang Zhu | Wen-Qi Cao | Wen He | Xiu-Yu Shi | Guang Yang | Li-Ping Zou

RAB24 maps comprehensive clinical landscapes and mediates tumor malignant progression under the epigenetic regulation of miR-30b-3p and MMP11 in clear cell renal cell carcinoma

July 2026

Fangshi Xu | Qiao Du | Gang Li | Lingyu Guo | Jiancang Ma | Zhenlong Wang

SF3B1K700E-driven transcriptional alterations in hematopoietic progenitors underlie blood cancer pathophysiology

July 2026

Mengzhu Xue | Jianhong An | Erqiang Hu | Wenjun Deng | Shanye Yin

Circulating tumor DNA predicts tumor recurrence in early-stage breast cancer: A meta-analysis

July 2026

Luke F. Moat | John G. Mayer | David S. Puthoff | Adam M. Bissonnette | Abdul R. Shour | Scott J. Hebbring | Adedayo A. Onitilo | Zhi Wen

UCH-L1 down-regulates HER2 expression and increases lapatinib sensitivity by interacting with HSP90 in HER2-positive breast cancer

July 2026

Min Zheng | Xisha Chen | Wenqiang Gan | Lei Hou | Zhongmei Zhou | Ceshi Chen | Zhenzhen Liu | Yan Cheng

Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response

July 2026

Tanya Singh | Kubra Trabzonlu | Aleksandra Spasova | Phil Stephens | David E.J. Linden | Marianne B.M. van den Bree | Michael J. Owen | Jeremy Hall | Ujjwal Neogi | Adrian J. Harwood | Yasir Ahmed Syed

Arctigenin derivative (ARC-18) improved mitochondrial dysfunction and ameliorated frataxin deficiency symptoms via PGC-1α signaling

July 2026

Qichao Gong | Xiao Han | Tiansu Liu | Bocheng Xiong | Bingge Zhang | Yongmei Xie | Huali Wan | Tahir Ali | Xifei Yang | Shupeng Li

Aminopyridine treatment for an adult patient of developmental and epileptic encephalopathy with a gain-of-function mutation in KCNA2

July 2026

Lehong Gao | Yu Jia | Yingxue Yang | Jia Chen | Liankun Ren

Identification of a novel prognostic gene signature associated with therapeutic resistance in hepatocellular carcinoma

July 2026

Siliang Wang | Shuangshuang Wang | Xu Wang | Yuxiang Sun | Xiao Du | Dan Han | Huanyu Ni | Yun Zhu | Huilian Shi | Zhaocong Yang

APE1 inhibition-promoted pyroptosis triggers T-cell infiltration and enhances anti-tumor immunity in NSCLC

July 2026

Fan Yang | Kaili Long | Yannan Qi | Yuwei Dai | Feiyan Pan | Lingfeng He | Lindong Yang | Zhigang Guo | Zhigang Hu

Juvenile idiopathic arthritis-associated RIG-I S144F variant inhibits type I interferon signaling by blocking TRIM25-mediated ubiquitination

July 2026

Li Zhang | Song Zhang | Yaoyao Shangguan | Wanming Huang | Haolan Jin | Lili Li | Yuyin Qi | Yuxia Zhang | Ping Zeng | Huifang Xian

RFX3 loss disrupts non-coding RNA networks in iPSC-derived pancreatic progenitors

July 2026

Noura Aldous | Aldana Alnesf | Ahmed K. Elsayed | Bushra Yasin Abohalawa | Nehad M. Alajez | Essam M. Abdelalim

Cis-regulation of FAM49A by a risk variant at 2p24 contributes to the genetic susceptibility of NSCL/P

July 2026

Junyan Lin | Xiaofeng Li | Ji Mao | Xinyu Zhang | Tingting Cheng | Yue Gao | Shu Lou | Dandan Li | Yongchu Pan

Comprehensive pan-cancer analysis reveals prognostic significance of CENPM and its role in immune infiltration

July 2026

Jinyuan Tang | Sihang Zhang | Yongshuai Jiang | Mingming Zhang

Ten-eleven translocation 2-mediated DNA demethylation plays a positive regulatory role in BMP9-induced osteogenic differentiation of mesenchymal stem cells

July 2026

Connie Chen | Yi Zhu | Sarina Zhao | Michelle Xiang | Chao Yu | Yan Peng | Yuting Liang | Jeffrey Baek | Longwei Qiao | Xiangyu Dong | Fangyi Yao | Jinglin Huang | Tong-Chuan He | Russell R. Reid | Jiaming Fan | Gregory Schimizzi | Sofia Bougioukli | Yong Xu | Changqi Luo

Up-regulated IL-36 expression promotes a pro-tumorigenic phenotype in pancreatic ductal adenocarcinoma

July 2026

Jianhong An | Quanxing Liao | Ziqin Yu | Zihao Du | Juan Du | Qiang Xiao | Tingting Jiang | Changwen Huang | Keping Xie

Multi-omics Mendelian randomization to identify novel immune therapeutic targets in benign prostatic hyperplasia

July 2026

Zhenpeng Zhu | Xing Ji | Wenyuan Leng | Weimin Hu | Chunru Xu | Xiaoyu Li | Jinqin Qian | Cuijian Zhang | Jian Lin

Novel mechanisms and transcription factors associated with the therapeutic effect of Jakyakgamcho-tang on neuropathic pain

July 2026

Su-Jin Baek | Musun Park | A Yeong Lee | Jin-Mu Yi | Sang-Min Park | Seongwon Cha | No Soo Kim

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