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ISSN: 2352-3042
CN: 50-1221/R
p-ISSN: 2352-4820

lncRNA POU3F3 promotes osteosarcoma progression through GPX4-modulated ferroptosis by interaction with IGF2BP2 to facilitate NRF2 mRNA stability

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VEXAS syndrome caused by a UBA1 mutation is complicated by recurrent infections leading to hemophagocytic lymphohistiocytosis

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Elucidating the pathogenesis of bladder cancer through single-cell chromatin accessibility and DNA methylation analysis

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Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction

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RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish

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Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles

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FGFR1 inhibition by carvacrol: A novel strategy for oral squamous cell carcinoma therapy

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Identification of a tertiary lymphoid structure (TLS)-related signature for ovarian cancer prognosis suggests a potential role of STAT5A in TLS maturation

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Enhancer profiling uncovers Jmjd1c as an essential suppressor in neuropathic pain by targeting Socs3

Neuropathic pain (NP) is a chronic debilitating disease caused by nerve damage or various diseases, significantly impairs patients’ quality of life. Super-enhancers (SEs) are important cis-regulatory...

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MyoAAV-delivered sup-tRNA increases full-length dystrophin expression

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Gene-based safety evaluation of molybdenum-containing biomaterials for cardiovascular and cerebrovascular diseases

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Identification of a splice site mutation in IL2RG in a Chinese boy with X-linked severe combined immunodeficiency

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Clinical impact of the TPM1 p.Tyr221Cys variant causing hypertrophic cardiomyopathy

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Integrating spatial transcriptomics and single-cell RNA-sequencing reveals epithelial cell alterations in benign prostatic hyperplasia following finasteride treatment

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HOPX inhibits skin cutaneous melanoma growth and induces macrophage M1 polarization

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Identifying functional subtypes and common mechanisms of rheumatoid arthritis and systemic lupus erythematosus

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Multi-omics analysis of epigenetic dysregulation reveals clinical heterogeneity and evaluates the immunotherapeutic potential of lung adenocarcinoma

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circFOXO3 facilitated endothelial cell senescence and atherosclerosis through binding to HnRNPK

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Deciphering the molecular landscape of oral squamous cell carcinoma: Novel biomarkers and therapeutic targets

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Gene jigsaw: Decrypting the CPAMD8 puzzle in Chinese patients with anterior segment dysgenesis

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Crowdedness imposes stress on tumor metastasis in Drosophila melanogaster

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Glial subtype-specific modulation of disease pathogenesis in Drosophila models of ALS

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Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency

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