Simultaneous determination of concentration of sulfamethoxazole and trimethoprim in human plasma by dual-quaternary HPLC and its clinical application
December 2024
Sulfamethoxazole compound, a combination of sulfamethoxazole and trimethoprim, is commonly prescribed to organ transplant recipients for infections caused by Nocardia, Burkholderia cepacia, and Pneumocystis...
Therapeutic drug monitoring for promotion of rational medication in the elderly: Overview, challenges and opportunities
November 2024
In the context of rapid development of clinical pharmacy in China, therapeutic drug monitoring (TDM) has become a vital tool for rational medication and is widely concerned. TDM combines the knowledge...
Precision individualized medication strategies and challenges for cardiovascular diseases
November 2024
With the ongoing societal development and changes in lifestyle, the incidence of cardiovascular diseases continues to rise. Although the most effective means of preventing atherosclerotic cardiovascular...
Unlocking precision medicine: Innovative strategies for druggable target identification and therapeutic enhancement
November 2024
Precision medication emphasizes tailored treatment approaches based on individual patient characteristics, yet the limitations in current drug target identification hinder therapeutic advancements....
Surgical pharmacy for catalyzing pharmacy service throughout surgical continuum
November 2024
The greater the complementarity between pharmacists’ knowledge and doctors’ knowledge, the more significant the role pharmacists can play in clinical practice. Physicians extensively use drugs for disease...
Current status and prospects of nucleic acid mass spectrometry in clinical pharmacogenomics
November 2024
Pharmacogenomics is an essential means to achieve personalized medicine. Multi-gene and multi-loci panel testing is an inevitable trend in its development, comprehensively analyzing the impact of genes...
Integrating pharmacy practice into precision emergency medicine: A pathway to enhanced patient care
November 2024
Precision emergency medicine (EM) represents a transformative approach to healthcare, integrating advanced technologies and human-centric data to tailor treatments to individual patient needs. This...
Towards precision medicine: Leading with big data and multidisciplinary collaboration
November 2024
Precision medicine relies on individuals’ genetic information, omics characteristics, and environmental factors to achieve personalized disease prevention, diagnosis, and treatment. With the successful...
Research progress on regulation of mitochondrial function by traditional Chinese medicine in alleviating acetaminophen-induced liver injury
November 2024
Drug-induced liver injury is a significant contributor to cases of acute liver failure and the primary reason for drug withdrawal due to safety concerns. Acetaminophen (N-acetyl-para-aminophenol, APAP)...